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Öğe Atypical presentations of celiac disease(Turkish J Pediatrics, 2011) Celiloglu, Can; Karabiber, Hamza; Selimoglu, Mukadder AyseCeliac disease (CD) has a wide variety of clinical presentations; together with the classical form, in which the intestinal symptomatology is prevalent, there are atypical forms with predominating extra-intestinal clinical features, and the silent form, with no clinical symptom. The atypical forms of the disease are characterized by few or no gastrointestinal symptoms, and predominating extra-intestinal features such as neurologic, dermatologic, hematologic, endocrinologic, reproductive, renal, psychiatric, skeletal, and liver involvement(s). Silent presentation of CD may be identified through screening of high-risk groups. Today, it is well known that CD might account for several chronic health issues, so it is essential for healthcare professionals to have a high level of suspicion for the atypical presentations of CD.Öğe Diagnostic Contribution of Postmortem Needle Biopsies in Neonates(De Gruyter Open Ltd, 2013) Celiloglu, Ozgu Suna; Celiloglu, Can; Kurnaz, Erdal; Ozdemir, Ramazan; Karadag, AhmetObjective: We examined the contribution of neonatal postmortem needle biopsy in circumstances of autopsy denial where magnetic resonance imaging cannot be performed. Material and Method: 247 postmortem needle biopsy specimens of 76 neonatal cases who died in the neonatal intensive care ward of a tertiary hospital between 2005 and 2010 and where the family did not give permission for an autopsy were retrospectively evaluated. Results: 90 needle biopsy attempts (36.4%) were unsuccessful among the 247 biopsies. Liver needle biopsies were found to yield the most valuable diagnostic contribution. A total of 53 liver biopsies provided clinical information that contributed to the diagnosis. Conclusion: The postmortem needle biopsy should be applied in all cases in which standard biopsy cannot be performed. Success rates and level of information gained by extrahepatic needle organ biopsies in neonates were found to be quite low whereas needle biopsies of the liver yielded valuable results. We believe it is more appropriate to perform percutaneous postmortem biopsies solely on the liver in neonates.Öğe Jeune Sendromu(İnönü Üniversitesi Tıp Fakültesi Dergisi, 2011) Celiloglu, Ozgu Suna; Dogan, Metin; Ak, Muharrem; Dogan, Derya Gumus; Celiloglu, Can; Sigirci, Ahmet; Karadag, AhmetJeune sendromu; diğer adıyla ‘Asfiksik Torasik Displazi’ (ATD) daralmış göğüs kafesi, ekstremite anomalileri, solunum yetmezliği ve kayda değer yenidoğan mortalitesi ile karakterize otozomal resesif kalıtım gösteren nadir bir kondrodisplazidir. Bu sendrom bulunan çocukların çoğu şiddetli solunumsal yetmezlik gösterir ve erken süt çocukluğu döneminde ciddi ventilatör desteğine ihtiyaç duyabilir. Sendromun renal displazi, retinitis pigmentosa, hepatik ve pankreatik fibrozu içerebilen geniş bir klinik spektrumu mevcuttur. Doğum öncesi akondroplazi tanısı bulunan ve doğum sonrası ciddi solunumsal yetmezlik gösteren ve Jeune sendromu tanısı konulan bir hastayı sunduk.Öğe Long-term benefits of breastfeeding(Turkish Pediatrics Assoc, 2010) Selimoglu, M. Ayse; Celiloglu, Ozgu Suna; Celiloglu, CanExclusively breastfeeding during the first six months of life is a worldwide accepted mode of feeding infants. Breast milk not only provides the needs of the infant for appropriate growth and development, but also lowers the mortality and morbidity by protecting against infections. It may also have some benefits for the following years and even for the adulthood. Numerous studies conducted on the late effects of breastfeeding reported sometimes inconsistent findings. We hope that review including last scientific knowledge would be helpful for physicians who deal with pregnants, newborns and infants to remember the benefits of breastfeeding. (Turk Arch Ped 2010; 45: 309-14)
