Yazar "Ceylan, Cengiz" seçeneğine göre listele
Listeleniyor 1 - 11 / 11
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Coagulopathy in multiple traumas(Ulusal Travma ve Acil Cerrahi Dergisi, 2010) Turtay, Muhammet Gökhan; Kırımlıoğlu, Vedat; Ceylan, CengizÖz: AMAÇ Erken dönemde genel vücut travmalı (GVT) hastalarda, kafa travmasının ve diğer bölge travmalarının koagülasyon üzerine etkisi ve bu hastalarda koagülasyon parametreleri ile Glaskow Koma Skoru (GCS) ve travma şiddet skoru (ISS) ilişkilerinin araştırılması amaçlandı. GEREÇ VE YÖNTEM Acil servise GVT ile başvuran, 50 hasta (9 kadın, 41 erkek) çalışmaya alındı. Hastaların GCS, ISS, koagülasyon parametreleri düzeyleri belirlendi. GCS, ISS ile koagülasyon parametreleri arasında korelasyon değerlendirildi. Hastalar; önemli bir travma tespit edilmeyen (A), sadece kafa travması olanlar (B), kafa travması ve diğer bölge travması olanlar (C), kafa travması olmayan ancak diğer bölge travmaları olanlar (D) olarak ayrıldı. BULGULAR ISS ile uluslararası normalize oranı (INR), aktif parsiyel tromboplastin zamanı (aPTT), D-dimer ve fibrin yıkım ürünleri (FDP) düzeyleri arasında pozitif, ISS ile antitrombin (AT) ve fibrinojen düzeyleri arasında negatif bir ilişki saptandı (p<0,05). C grubuyla diğer gruplardaki INR, D-dimer, fibrinojen, aPTT, AT parametreleri karşılaştırıldığında istatistiksel anlamlılık saptandı (p<0,05). Kafa travması olan ve olmayan gruplar arasındaki INR, D-dimer ve fibrinojen parametrelerinde istatistiksel anlamlılık saptandı (p<0,05). SONUÇ Kafa travması olan hastalarda koagülasyon parametrelerinin bozulduğu, ancak kafa travmasına diğer bölge travmaları eşlik ettiğinde koagülasyon parametrelerinin daha fazla anormalleştiği belirlendi. Başlık (İngilizce): Çoklu travmalarda koagülopati Öz (İngilizce): BACKGROUND This study aimed at analyzing the effect on coagulation of head trauma and other local traumas in patients exposed to multiple traumas in the early stage, and also the relations of Glasgow Coma Scale (GCS) and Injury Severity Score (ISS) with coagulation parameters in these patients. METHODS Fifty consecutive patients (9 women, 41 men) with multiple traumas were included in this study. The GCS, ISS and coagulation parameter levels were measured. Presence of a correlation between GCS and ISS with coagulation parameters was analyzed. Patients exposed to multiple traumas were assessed in four categories as the patients with no significant traumas (A), only head traumas (B), head trauma and other local traumas (C), and no head traumas but other local traumas (D). RESULTS A marked relationship was found between ISS and international normalized ratio (INR), activated partial thromboplastin time (aPTT), D-dimer, fibrin degradation product (FDP), antithrombin (AT), and fibrinogen (p<0.05). There was a statistically significant difference between Group C and the other groups in INR, D-dimer, fibrinogen, aPTT, and AT parameters (p<0.05). There was also a statistically significant difference between the groups with and without head trauma in INR, D-dimer and fibrinogen (p<0.05). CONCLUSION The coagulation parameters were observed to diverge in patients with head trauma, but in cases with head injuries accompanying other local traumas, more coagulation parameters became abnormal.Öğe Effectiveness of X-ray film in diagnosing peptic ulcer perforation(2024) Ceylan, Cengiz; Bilen, Zafer; Aydın, CemalettinPurpose: A retrospective case-control study was undertaken to assess the diagnostic efficacy of X-ray film in detecting peptic ulcer perforation (PUP). Materials and Methods: The study retrieved demographic data, perioperative observations, and postoperative results of 353 patients from the hospital repository. These individuals were categorized into two cohorts depending on the detection of intraperitoneal free air on X-ray imaging. Results: The study cohort exhibited a median age of 57 years (interquartile range: IQR 38-71), comprising predominantly males (82.4%). Intraperitoneal free air was evident in 73.1% of patients on X-ray imaging. In the multivariate analyses of the respective groups, time interval and diabetes mellitus (DM) emerged as independent risk factors. Notably, the sensitivity of X-ray film heightened with prolonged duration between symptom onset and emergency department admission, while specificity increased in the presence of DM. Conclusion: The imperative for supplementary imaging modalities in conjunction with clinical assessment is apparent in the diagnostic approach to PUP. Nonetheless, the fluctuation in sensitivity and specificity of X-ray film concerning DM and the duration from symptom onset to emergency department admission warrants careful consideration. Especially in cases where clinical suspicion of PUP exists despite the absence of intraperitoneal free air on X-ray, the utilization of advanced diagnostic techniques is advocated.Öğe FACTORS IMPACTING MORTALITY IN TURKISH OCTOGENARIAN AND NONAGENARIAN PATIENTS WHO UNDERWENT COLORECTAL SURGERY(Medical & Surgical Research Journals Group, 2022) Ceylan, Cengiz; Ocakli, Serhat; Akinci, Felat; Cetinkaya, Erdinc; Agackiran, Ibrahim; Akin, Tezcan; Er, SadettinBackground & objective: Due to their physiological conditions, the postoperative mortality rates of elderly patients are higher compared to other age groups, albeit the postoperative care and intensive care conditions are better than in the past. In this retrospective study, it was aimed to present a model to predict mortality and factors affecting mortality in this patient group who underwent colorectal surgery. Material & Methods: The population of octogenarian and nonagenarian patients who were operated for colorectal surgery in our clinic between 2020 and 2021 were included in the study. Patients' age, gender, albumin, lymphocyte, monocytes, lymphocyte-monocyte ratio (LMR), prognostic nutritional index (PNI), delta neutrophil index (DNI), Charlson comorbidity index (CCI), length of hospital stay, modified systemic inflammatory score (mSIS)) values, operation type (emergency/ elective), operation classification (minor/ moderate/ major/ complex major), anesthesia type (general/ epidural), and contamination status (clean/ clean-contaminated/ contaminated/ dirty or infected) were obtained from the hospital system. Results: Case status, operation type, contamination status, DNI, duration of hospitalization, mSIS variables were statistically significant in univariate regression analyses. However, in multivariate regression analyses, DNI of >= 0.05 (p< 0.015; OR 3.984, 95%CI 1.302-12.195) and contamination status (p< 0.038; OR 13,047, 95%Cl 1,150-148,087) were found to be independent risk factors affecting postoperative mortality. Conclusion: In the geriatric patient population undergoing colorectal surgery, DNI and contamination of the surgical field are two important factors affecting mortality. We think that the mortality estimation model created for this patient population will also help physicians for the postoperative period of the patients.Öğe The feasibility of falciformopexy in the repair of peptic ulcer perforation(Turkish Assoc Trauma Emergency Surgery, 2023) Terzioglu, Serdar Gokay; Canlikarakaya, Firat; Ocakli, Serhat; Ceylan, Cengiz; Agackiran, Ibrahim; Akinci, Felat; Kilic, Murat OzguerBACKGROUND: Modified Graham omentopexy is the most commonly used operative technique in the repair of peptic ulcer perforation (PUP); however, there is little data on falciformopexy in the literature. The aim is to investigate the feasibility of falciformopexy in the repair of PUP, comparing with modified Graham omentopexy.METHODS: Data of 471 patients who were operated for PUP were retrospectively analyzed. Patients' demographics, pre-operative basic laboratory findings, American Society of Anesthesiologists (ASA) status, operative findings, and post-operative complications were recorded. The patients were classified into two groups modified Graham omentopexy and falciformopexy, and then compared with each other in terms of clinical characteristics, operative findings, and post-operative complications.RESULTS: Modified Graham omentopexy and falciformopexy were performed in 425 (90.2%) and 46 (9.8%) patients, respectively. The two groups were similar in terms of basic patient characteristics and pre-operative laboratory findings (P>0.05). ASA physical status was significantly different between the groups (P=0.001). No statistically significant difference was found between the groups in terms of complications, except for an anastomotic leak. Anastomotic leak was observed more frequently in patients who underwent falciformopexy than in patients with modified Graham omentopexy (P=0.017). CONCLUSION: Although falciformopexy technique has a higher rate of leak compared to the modified Graham omentopexy method, it should be kept in mind as an alternative method for repair of PUP, especially in cases where omentopexy cannot be applied for various reasons such as the presence of unavailable or unsuitable omentum.Öğe Firearm injury and the Deloyers procedure: case report and literature review(Turkish Assoc Trauma Emergency Surgery, 2024) Ceylan, CengizFollowing extended colon resections, it may not always be possible to perform colorectal anastomosis. The Deloyers procedure, which involves the transposition of the right colon, has been identified as a viable solution. This report aims to discuss the circumstances under which the Deloyers procedure was performed, as well as to evaluate the early and late postoperative outcomes, by reviewing cases conducted between 2010 and 2023. In a 22 -year -old female patient who suffered major organ and tissue loss (with injuries to the sigmoid colon, descending colon, transverse colon, and mesentery) due to a firearm injury, the Deloyers procedure was applied during restorative surgery following initial damage control surgery. The procedure involved mobilizing the cecum and right colon, performing a cranio-caudal rotation over the ileocolic artery pedicle, followed by an appendectomy, and creating a colorectal anastomosis using circular staplers. There were no complications during the postoperative follow-ups. By the 14th postoperative day, the patient was discharged and experienced bowel movements four times a day, managed with 2.5 mg of diphenoxylate hydrochloride and 0.025 mg of atropine sulfate. At the 6 -month follow-up, the frequency of bowel movements had decreased to twice daily without the need for medical treatment. Given the functional outcomes in patients after extended left colectomies, the Deloyers procedure, with its low associated morbidity, stands out as a viable option.Öğe The Importance of Minimal Cortex Thickness of the Lymph Node in Axillary Ultrasound for Early-stage Breast Cancer(Springer, 2023) Cangoz, Kayra; Menekse, Ebru; Elverici, Eda; Ozsoy, Arzu; Ceylan, Cengiz; Korukluoglu, Birol[Abstract Not Available]Öğe Is the appropriate timing for percutaneous cholecystostomy in acute cholecystitis a matter of concern?(Turkish Assoc Trauma Emergency Surgery, 2024) Ceylan, Cengiz[Abstract Not Available]Öğe A new model for prediction of bowel gangrene in sigmoid volvulus(Turkish Assoc Trauma Emergency Surgery, 2023) Ceylan, Cengiz; Baran, Necip Tolga; Kocaaslan, Huseyin; Gungorur, Omer; Cengiz, Emrah; Guzel, Mehmet; Angin, Yavuz SelimBACKGROUND: Sigmoid volvulus is a pathology that can be mortal because it is frequently encountered in elderly patients. In case of bowel gangrene, mortality and morbidity increase further. We planned a retrospective study, in which the effectiveness of the model was evaluated by creating a model that aims to predict whether intestinal gangrene is present in patients with sigmoid volvulus only by blood tests and thus to quickly guide treatment methods.METHODS: In addition to demographic data such as age and gender, laboratory values such as white blood cell, C-reactive protein (CRP), lactate dehydrogenase (LDH), potassium, and colonoscopic findings and whether there was gangrene in the colon during the operation were evaluated retrospectively. In the analysis of the data, independent risk factors were determined by univariate and multivariate logistic regression analyzes as well as Mann-Whitney U and Chi-square tests. Receiver operating characteristic (ROC) analysis was performed for statistically significant continuous numerical data, and cutoff values were determined and Malatya Volvulus Gangrene Model (MVGM) was created. The effectiveness of the created model was again evaluated by ROC analysis.RESULTS: Of the 74 patients included in the study, 59 (79.7%) were male. The median age of the population was 74 (19-88), and gangrene was detected in 21 (28.37%) patients at surgery. In univariate analyzes, leukocytes <4000/mm3 and >12000/mm3 (OR: 10.737; CI 95%: 2.797-41.211, p=0.001), CRP >= 0.71 mg/dl (OR: 8.107 CI 95%: 2.520-26.082, p<0.0001), potassium >= 3.85 mmoL/L (OR: 3.889; 95% CI): 1.333-11.345, p=0.013), and LDH >= 288 U/L (OR: 3.889; CI 95%: 1.333-11.345, p=0.013), whereas, in multivariate analyzes, only CRP >= 0.71 mg/dL (OR: 3.965; CI 95%: 1.071-15.462, p=0.047) was found to be an independent risk factor for bowel gangrene. The strength of MVGM was AUC 0.836 (0.737-0.936). In addition, it was observed that the probability of bowel gangrene increased approximately 10 times if MVGM was >= 7 (OR: 9.846; 95% CI: 3.016-32.145, p<0.0001).CONCLUSION: Besides being non-invasive compared to the colonoscopic procedure, MVGM is a useful method for detecting bowel gangrene. In addition, it will guide the clinician in taking the patients with intestinal loop gangrene to emergency surgery without wasting time in the treatment steps, as well as avoiding complications that may occur during colonoscopy. In this way, we think that morbidity and mortality rates can be reduced.Öğe Predictive Factors of Postoperative Pancreatic Fistula in Geriatric Patients Undergoing Pancreatoduodenectomy for Periampullary Malignancy(Coll Physicians & Surgeons Pakistan, 2023) Ceylan, Cengiz; Kocaaslan, Huseyin; Baran, Necip Tolga; Kulus, Mehmet; Saglam, Kutay; Aydin, CemalettinObjective: To identify predictive factors associated with the occurrence of postoperative pancreatic fistula (POPF) following pancreato-duodenectomy (PD) in an increasingly geriatric population.Study Design: Observational study.Place and Duration of the Study: Department of General Surgery, Inonu University, Malatya, Turkey, from January 2010 to April 2022.Methodology: Demographic and clinicopathological data of 74 geriatric patients who underwent PD for periampullary tumours in the clinic at Inonu University were retrieved from the patient database. POPF was defined and categorised based on the guidelines established by the International Study Group for Pancreatic Surgery (ISGPS). The patients were stratified into two cohorts of POPF and no POPF. Univariate and multivariate analyses were conducted to compare variables between the two groups.Results: The median age of the patient population was 72 (65-92) years, and 51 (68.9%) individuals were male. Among the 74 patients, 35 (47.3%) experienced POPF. In the multivariate analysis, hypertension (HT, p=0.012), Wirsung diameter <3.5 mm (p<0.01), and pancreaticojejunostomy (PJ, p=0.022) emerged as independent risk factors for POPF.Conclusion: In the context of geriatric patients undergoing PD, HT, intraoperative wirsung diameter <3.5 mm, and PJ were identified as independent risk factors for POPF. These findings can guide the adoption of safer techniques in preoperative and intraoperative evaluations, as well as in postoperative follow-ups of patients presenting with these risk factors.Öğe Preoperative predictive factors affecting sentinel lymph node positivity in breast cancer and comparison of their effectiveness with existing nomograms(Lippincott Williams & Wilkins, 2022) Ceylan, Cengiz; Ozel, Hikmet Pehlevan; Agackiran, Ibrahim; Ozdemir, Buket Altun; Atas, Hakan; Menekse, EbruThis study aimed to establish a strong regression model by revealing the preoperative predictive factors for sentinel lymph node (SLN) positivity in patients with early stage breast cancer (ESBC). In total, 445 patients who underwent SLN dissection for ESBC were included. All data that may be potential predictors of SLN positivity were retrospectively analyzed. Tumor size >2 cm, human epidermal growth factor receptor 2 (HER2) + status, lymphovascular invasion (LVI), palpable tumor, microcalcifications, multifocality or multicentricity, and axillary ultrasonographic findings were defined as independent predictors of SLN involvement. The area under the receiver operating characteristic (ROC) curve (AUC) values were 0.797, 0.808, and 0.870 for the Memorial Sloan-Kettering Cancer Center (MSKCC) nomogram, MD Anderson Cancer Center (MDACC) nomogram, and our regression model, respectively (P < .001). The recent model for predicting SLN status in ESBC was found to be stronger than existing nomograms. Parameters not included in current nomograms, such as palpable tumors, microcalcifications, and axillary ultrasonographic findings, are likely to make this model more meaningful.Öğe THE RELATION BETWEEN MODIFIED SYSTEMIC INFLAMMATION SCORE AND PROGNOSTIC MARKERS OF GASTROINTESTINAL STROMAL TUMORS(2023) Canlıkarakaya, Fırat; Ocaklı, Serhat; Ceylan, Cengiz; Göktaş, Abidin; Güler, İlkay; Terzioğlu, Serdar GökayObjective Gastrointestinal stromal tumours are tumours of mesenchymal origin that can be located along the gastrointestinal tract. In this study, the role of Modified systemic inflammation score in predicting the prognosis of these tumours was investigated. Material and Method 115 patients diagnosed with Gastrointestinal Stromal Tumor (GIST) who underwent surgery at Ankara City Hospital between June 1, 2019 and December 1, 2022 were examined. Tumor location, size, presence of rupture-bleeding-necrosis, Ki-67 level, mitotic index and preoperative albumin, lymphocyte and monocyte levels were evaluated. mSIS score was grouped as 0, 1 and 2. The relationship between mSIS and Ki- 67 index and the presence of rupture, necrosis and bleeding was investigated. Results Out of 115 patients, 68 (59 %) were male, 47 (41 %) were female, with an average age of 62.5 (± 12.67) years. Tumor locations: stomach (64.3 %), small intestine (26 %), colon (5.2 %), esophagus (1.8 %), pancreas (1.8 %), and ovary (0.9 %). Necrosis was in 25 (30.7 %), hemorrhage in 67 (58.7 %), rupture in 19 (16.8 %), and the mean Ki-67 level was 9.09 (± 10.64). 63 (54.8 %) patients had mSIS 0, 29 (25.2 %) had mSIS 1, and 23 (20 %) had mSIS 2. Statistical analysis found a significant correlation between mSIS and necrosis, but not with other parameters. Conclusion The mSIS score is a valuable score showing inflammation in the body and has been shown to be associated with the prognosis of many malignancies. In our study, the presence of necrosis in the tumour was found to be associated with the mSIS score. Although this result alone is not sufficient to predict the prognosis, it is thought to be an issue that may open the door to new studies.
