Impact of Prognostic Nutritional Index on Prognosis in Geriatric Patients Undergoing Surgical Intervention for Colorectal Cancer
Küçük Resim Yok
Tarih
2025
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer India
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The Prognostic Nutritional Index (PNI) is a valuable and informative indicator for clinicians. This study aims to investigate the impact of PNI on long-term survival in the geriatric population diagnosed with colorectal cancer. In this study, we collected demographic and clinicopathological data from 147 geriatric patients who underwent colorectal surgery at our institution between 2013 and 2022. PNI values were calculated for each patient. Based on ROC analysis for mortality, patients were categorized into two groups: low PNI and high PNI. With a median follow-up period of 34 months, the long-term outcomes of these groups were analyzed. The low PNI group (PNI <= 34.5) was associated with colon cancers rather than rectal cancer (p = 0.014), older age (p = 0.004), and higher mortality (p = 0.006). Additionally, in the survival analysis, the mean overall survival was 92.44 SD6.41 months in the high PNI group, compared to 76.66 SD8.77 months in the low PNI group (p = 0.006). For geriatric patients diagnosed with colorectal cancer who have a preoperative PNI <= 34.5, it is recommended that clinicians provide both preoperative and postoperative nutritional support, considering its significant impact on overall survival.
Açıklama
Anahtar Kelimeler
Colorectal Cancer, Geriatric Patients, Prognostic Nutritional Index, Surgery
Kaynak
Indian Journal of Surgery
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
87
Sayı
SUPPL1
