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Öğe Annelerin bebekleri ile birlikte uyumaya ve ayrı uyumaya ilişkin görüşlerinin ve algılarının metaforik olarak incelenmesi(2024) Şentürk, Emine; Cumurcu, Hatice BirgülBu çalışmada, annelerin bebeklerinin ilk üç yılında birlikte uyumaya ve ayrı uyumaya ilişkin görüş ve algılarının metaforik olarak incelenmesi amaçlanmıştır. Araştırma deseni olarak nitel araştırma modeli kullanılmıştır. Çalışmaya 0-3 yaş çocuğu olan 38 anne katılmıştır. Veri toplama aracı olarak demografik bilgi formu ve araştırmacı tarafından oluşturulan yarı yapılandırılmış görüşme formları kullanılmıştır. Annelerin genellikle bebekleri ile aynı odada uyudukları, aynı odayı paylaşma sebeplerinin başında gece beslenmesi, bebeğin kendini güvende hissetmesi ve bağlanma duygusu gibi etkenlerin olduğu belirlenmiştir. Bebeklerin odalarının çoğunlukla 0-12 aylıkken ayrıldığı, bebek odasının ayrılmasındaki başlıca sebeplerin bebeğin rahatı ve bağımsızlığını sağlaması olduğu belirlenmiştir. Annelerin bebekleri ile aynı odada uyumaya ilişkin metaforları çoğunlukla huzur/sıcaklık ve koruma/kapsayıcılık temalarıyla ilişkilendirilirken, annelerin ayrı odalarda uyumaya ilişkin metaforları çoğunlukla kaygı ve huzursuzluk temalarıyla ilişkilendirilmiştir. Bebekleri ile aynı odada uyuyan anneler ayrı uyuma algılarını öncelikle endişe temasıyla ifade ederken, bebekleri ile ayrı odada uyuyan anneler ayrı uyuma algılarını öncelikle rahatlık temasıyla ifade etmişlerdir. Bebeğin yaşı ne olursa olsun annelerin bebekleriyle uyurken huzur ve sıcaklık hissettikleri ortaya çıkmıştır. Bebeğin mizacı ne olursa olsun annelerin bebeklerinden ayrı uyuduklarında kendilerini endişeli hissettikleri ortaya çıkmıştır.Öğe The effect of agoraphobia on oxidative stress in panic disorder(Psychiatry Investigation, 2013) Göğcegöz Gül, Işıl; Karlıdağ, Rıfat; Cumurcu, Hatice Birgül; Türköz, Yusuf; Özcan, Abdul Cemal; Erdemli, ErmanWe aimed to investigate whether agoraphobia (A) in panic disorder (PD) has any effects on oxidative and anti-oxidative parameters. We measured total antioxidant capacity (TAC), paraoxonase (PON), arylesterase (ARE) antioxidant and malondialdehyde (MDA) oxidant levels using blood samples from a total of 31 PD patients with A, 22 PD patients without A and 53 control group subjects. There was a significant difference between the TAC, PON, ARE and MDA levels of the three groups consisting of PD with A, PD without A and the control group. The two-way comparison to clarify the group creating the difference showed that the TAC, PON, and ARE antioxidants were significantly lower in the PD with A group compared to the control group while the MDA oxidant was significantly higher. There was no significant difference between the PD without A and control groups for TAC, PON, ARE and MDA levels. We clearly demonstrated that the oxidative stress and damage to the anti-oxidative mechanism are significantly higher in the PD group with A. These findings suggest that oxidative/anti-oxidative mechanisms may play a more important role on the pathogenesis of PB with A.Öğe Effect of the addition of ketamine to sevoflurane anesthesia on seizure duration in electroconvulsive therapy(The Journal of ECT, 2015) Erdil, Feray; Özgül, Ülkü; Çolak, Cemil; Cumurcu, Hatice Birgül; Durmuş, MahmutObjectives: We evaluated the effects of a subanesthetic dose of ketamine, which was administered as an adjunct to sevoflurane, on duration of seizure activity, hemodynamic profile, and recovery times during electroconvulsive therapy in patients with major depression. Methods: Patients were randomly allocated to a group receiving either sevoflurane-ketamine (group SK) or sevoflurane-saline (group SS). Sevoflurane was initiated in both groups at 8% for anesthesia induction until loss of consciousness was achieved, at which point it was discontinued. After loss of consciousness, ketamine was administered to the group SK in the form of a 0.5-mg/kg intravenous bolus. Patients in the group SS received saline in the same manner. Mean arterial pressure (MAP) and heart rate were recorded before anesthetic induction (T1); after anesthetic induction (T2); as well as 0, 1, 3, and 10 minutes after the seizure had ended (T3, T4, T5, and T6, respectively). Motor and electroencephalogram seizure durations were recorded. Results: Motor and electroencephalogram seizure durations in the group SS were similar to those observed for the group SK. The heart rate increased significantly during T2 to T6 in both group SS and group SK compared with the baseline. The MAP increased in the group SS during the period between T3 and T6 as well as in the group SK during the same period compared with the baseline. The MAP increased more in the group SK, in comparison with the group SS, during T2 (P < 0.05). Conclusions: The addition of ketamine at subanesthetic doses, for the purposes of anesthetic induction with sevoflurane, yielded results similar to those in the control group in terms of both seizure duration and hemodynamic stability.Öğe The neuropsychological and neurophysiological profile of women with pseudoseizure(Comprehensive Psychiatry, 2013) Han Almış, Behice; Cumurcu, Hatice Birgül; Ünal, Süheyla; Özcan, Abdulcemal; Aytaş, ÖzgürObjective: Our aim in this study was to compare the assessments of neuropsychological tests and the p50 neurophysiological test of patients with seizure diagnosed as conversion disorder and healthy control subjects, and to investigate the neurological status in conversion disorder with pseudoseizure. Methods: A total of 22 female conversion disorder patients with convulsions diagnosed according to SCID-I/CV and 22 healthy women were included in the assessment. The participants were administered WMS-R, the cancellation test, and the Stroop test as neuropsychological tests and p50 was assessed as a neurophysiological test. Results: The patient's results for the neuropsychological tests were found to be significantly low compared to the control group. The p50 sensory gating ratios of the patient group were statistically significantly lower than the controls. There was no significant correlation between the neuropsychological test scores and gating ratios of the patient and control groups. Conclusions: This study is the first to check sensory gating in conversion disorder patients with pseudoseizure and its most important result is finding reduced p50 sensory gating in patients. Our results suggest that these patients have a neurological tendency to this disease due to functional neurophysiological features.