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Öğe Comparison of fentanyl and ketamine addition to bupivacaine for caudal anesthesia in children(2004) Köro?lu A.; Gülhaş N.; Türköz A.; Erdem S.; Ersoy M.Ö.In our study, we aimed to compare the effects of fentanyl and ketamine addition to bupivacaine on the quality of anesthesia, level of sensorial block, duration of motor block, postoperative analgesic requirement and duration of postoperative analgesia for caudal anesthesia in children. One hundred twenty two patients aged between 1-8 years old undergoing inguinal hernia repair were included in the study. Mask anesthesia with sevoflurane was applied during intravenous catheter placement and propofol infusion 1-3mg kg-1 h-1 was given while performing caudal anesthesia and during the operation. In group I (n=43) 2mg kg-1 0.25% bupivacaine, in group II (n=40) 1?g kg-1 fentanyl and 2mg kg-1 0.25% bupivacaine, in group III (n=39) 0.5mg kg-1 ketamine and 2mg kg-1 0.25% bupivacaine was given. Mean blood pressure, heart rate, peripheral oxygen saturation, respiration rate, ETCO2 and total dose of propofol used were recorded. Onset time of block, levels of sensorial block, duration of motor block and postoperative analgesia, total analgesic amount and complications were recorded. Mean level of sensorial block was significantly higher in group II and III than group I. Analgesic requirement after operation was significantly lower in group III than group I. Duration of postoperative analgesia was significantly longer in group III than the other groups. As a conclusion, we decided that fentanyl or ketamine addition to bupivacaine does not affect the quality of caudal anesthesia, but ketamine decreased the analgesic requirement by extending duration of postoperative analgesia.Öğe Comparison of Hashin and Puck criterions for failure behavior of pin loaded composite plates(John Wiley and Sons Inc, 2024) Dogan C.; Kaman M.O.; Erdem S.; Albayrak M.In this study, the failure behavior of carbon fiber-reinforced pin-jointed composite plates were analyzed for different criteria. For this purpose, composite plates with a single and double pin joints were prepared from four layers carbon fiber composites. The effect of pin number, pin position on plate damage load and type was investigated experimentally and numerically under the tensile test. Numerically, progressive damage analysis was performed using Hashin and Puck failure criteria, and the approach rates to the experimental results were determined. It was observed that the experimental results obtained for single pin joint composites and the numerical data obtained using the Puck damage criterion were at least 87 % compatible, and this rate was determined as 85 % for the Hashin failure criterion. For the double pin jointed composites, it was seen that the experimental results and the results of the Puck damage criterion were compatible with at least 90 %, and this rate was obtained as 84 % for the Hashin failure criterion. The dominant damage type seen in the specimen is matrix shear and fiber compression according to the Hashin damage criterion, inter fiber failure in transverse tension for Puck. © 2024 Wiley-VCH GmbH.Öğe Effects of intrathecal fentanyl or meperidine addition to bupivacaine on hemodynamic variables, postoperative analgesic requirements, levels of histamine, IgE, basophiles and eosinophiles(2003) Köro?lu A.; Erdem S.; Çiçek M.; Do?an Z.; Sezgin N.; Ersoy M.O.The aim of our study is to compare the effects of intrathecal fentanyl and meperidine with bupivacaine on hemodynamics, postoperative analgesic requirement, side effects and levels of histamine, IgE, basophiles, eosinophiles and to investigate a possible relationship between itching and levels of basophiles and eosinophiles. Heart rate, mean arterial pressure, SpO2 values, respiration rates of 45 cases were recorded before and after spinal anesthesia. Intrathecal 10mg bupivacaine heavy was used in combination with 0.5 mL 0.9% NaCl in group B, 25 ?g fentanyl in group F, 25 mg meperidine in group M were given. Blood samples were collected to determine the plasma levels of histamine, IgE, basophiles and eosinophiles 30 min before spinal anaesthesia, and at the 8th, 60th minutes of spinal anaesthesia. Analgesic requirement was evaluated for postoperative 24 hours by using VAS. Although plasma levels of histamine and basophiles were significantly higher in group M and F at the 8th, 60th min of spinal anaesthesia, levels of histamine were significantly higher in group M than other two groups at the 8th min of spinal anaesthesia. VAS scores and analgesic requirements were significantly lower in group M than the other two groups at late postoperative period. Itching and vomiting incidences were higher in group F and there was no relationship between itching and levels of eosinophiles and basophiles. In conclusion, we determined that intrathecal fentanyl and meperidine did not effect hemodynamics, and meperidine provided better analgesia in the postoperative period. Although, histamine release increased with both opioids, it was more in meperidine than fentanyl, however fentanyl caused more vomiting and itching. There was no relationship between levels of eosinophiles, basophiles and itching.