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Öğe Balance, mobility, fear of falling and lower extremity agonist-antagonist muscle strength ratios in women with osteoporosis(B M J Publishing Group, 2007) Ersoy, Y.; MacWaiter, R. S.; Altay, Z. E.; Durmus, A.; Baysal, O.; Kucukkaya, E.[Abstract Not Available]Öğe Can the patient-reported outcome instruments determine disease activity in rheumatoid arthritis?(Aepress Sro, 2011) Durmus, B.; Altay, Z.; Baysal, O.; Ersoy, Y.; Erdal, A.; Cevik, R.; Ardicoglu, O.Objectives: The aim of this study was to investigate the indicative value of the patient-reported outcome instruments (PROs) on disease activity in rheumatoid arthritis (RA). Methods: Three hundred sixty eight patients with RA were included in this cross-sectional study. Disease activity was evaluated using both the Disease Activity Score 28 (DAS 28) and the Clinical Disease Activity Index (CDAI). Patients who had DAS 28 score <3.60 points and CDAI score <10.00 points were allocated into the low disease activity group and those who had DAS 28 score >= 3.60 points and CDAI score >= 10.00 points into the moderate or high disease activity group. The Health Assessment Questionnaire (HAQ), Nottingham Health Profile (NHP), Rheumatoid Arthritis Quality of Life (RAQoL), and Short Form 36 (SF 36) were used as PROs. Logistic regression analysis was used to find variables, which had an indicative value for disease activity. Results: HAQ, pain and emotional reaction subscales of NHP, and bodily pain, general health and social functioning subscales of SF 36 had independent indicative values, when DAS 28 was used as dependent variable. On the other hand, HAQ, pain and emotional reaction subscales of NHP, and general health and emotional role limitation subscales of SF 36 had indicative values when CDAI was used as dependent variable. DAS 28 and CDAI both showed HAQ as the parameter with the highest odds ratio (OR). But RAQoL had shown no independent indicative value for projecting disease activity. Conclusion: It was concluded that HAQ could determine disease activity in RA better than other PROs included in this study (Tab. 4, Ref. 36). Full Text in free PDF www.bmj.sk.Öğe Community-acquired acute bacterial meningitis in the elderly in Turkey(Elsevier Sci Ltd, 2010) Erdem, H.; Kilic, S.; Coskun, O.; Ersoy, Y.; Cagatay, A.; Onguru, P.; Alp, S.P>This investigation aimed both to delineate the current status of community-acquired acute bacterial meningitis and to produce data on the interrelationships between clinical, laboratory and therapeutic parameters in the elderly. This retrospective cohort study was conducted in 28 Turkish institutions in 159 culture-positive patients over the age of 50 years. Streptococcus pneumoniae was the most common pathogen (69.2%), followed by Listeria monocytogenes (8.8%). For this reason, antilisterial antibiotics such as ampicillin or benzylpenicillin should be added to the therapeutic regimen. Pathogen-specific mortality did not vary between S. pneumoniae and L. monocytogenes. The overall mortality was 2.5% at the third day, 12.6% at the seventh day, 20.1% at the 14th day and 21.4% at the 21st day. The risk factors for fatality were increasing age, the presence of stupor, sepsis and inappropriate antibiotic administration. Cerebrospinal fluid (CSF) leukocyte counts and CSF/blood glucose ratios were lower in patients who died. Fever did not differ between survivors and fatal cases. The mean duration of antibiotic therapy in survivors was 16.3 +/- 6.4 days. One-fifth of the patients had complications, and in 5.7% of the patients sequelae persisted at follow-up.Öğe Isokinetic evaluation of knee extensor/flexor muscle strength in Behcet's patients(Publisaude-Edicoes Medicas Lda, 2015) Durmus, B.; Emre, S.; Sahin, N.; Karincaoglu, Y.; Dogan, E.; Baysal, O.; Ersoy, Y.Background: Behcet's disease (BD) is an idiopathic, multisystemic, progressive disease. The purpose of this study is to compare the knee flexor and extensor isokinetic muscle strengths of Behcet's patients with that of healthy subjects. Methods: Twenty-five (13 male and 12 female) patients with BD and 25 (15 male and 10 female) healthy individuals were included in the study Velocities of 90 degrees/sec, 120 degrees/sec, and 150 degrees/sec were used for the isokinetic muscle strength testing. Patients with active inflammatory knee arthritis were excluded. Peak torque (Nm) and peak torque adjusted to body weight (%) were taken into consideration for comparison between study groups. Results: Compared to healthy controls, there was a statistically significant decrease in both the bilateral knee extensor and flexor muscle isokinetic peak torques (Nm) as well as the peak torques adjusted to body weight (%) at velocities of 90 degrees/sec, 120 degrees/sec and 150 degrees/sec in patients with BD (p < 0.05). However, there was no significant difference in the agonist-antagonist ratio of the isokinetic peak torques of knee muscles between the two groups. Conclusion: In light of these findings, we have concluded that both knee flexor and extensor isokinetic muscle strengths are lower in BD. We therefore recommend careful monitoring of patients with BD in temis of muscle strength.Öğe Outbreak of adenovirus serotype 8 conjunctivitis in preterm infants in a neonatal intensive care unit(W B Saunders Co Ltd, 2012) Ersoy, Y.; Otlu, B.; Turkcuoglu, P.; Yetkin, F.; Aker, S.; Kuzucu, C.Background: Adenovirus keratoconjunctivitis outbreaks have rarely been reported in preterm infants. An outbreak of adenovirus conjunctivitis occurred between 15 January and 25 February at a neonatal intensive care unit of a university hospital in Turkey. Aim: To describe the evolution, investigation and management of the outbreak. Methods: Adenovirus type 8 was identified in 14 samples by polymerase chain reaction analysis. A case-control study was performed to determine the risk factors. Findings: Fifteen preterm neonates, five healthcare workers (HCWs) and four parents suffered from conjunctivitis signs such as lacrimation, swelling and redness of the eye. A retinopathy of prematurity (ROP) examination was found to be the most important risk factor for adenovirus conjunctivitis (odds ratio: 17.5; 95% confidence interval: 1.9-163.0; P=0.012). The eyelid speculum (blepharostat) used during the ROP examination was not sterilized between each patient and was found to be the cause of contamination. Conclusion: The outbreak was controlled by measures such as barrier precautions, hand hygiene, sterilization of the blepharostat, suspending patient transfer to other units, and excluding infected HCWs for at least 15 days. (C) 2011 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
