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    Effects of Lycium barbarum on bacterial translocation in thioacetamide induced liver injury in rats
    (European Journal of Inflammation, 2015) Bilgiç, Yılmaz; Harputluoğlu, Murat; Kutlu, O; Demirel, Ulvi; Gül, Mehmet; Otlu, Barış; Temel, İsmail; Gürsoy, S.; Dertli, Ramazan; Selçuk, Engin Burak; Yılmaz, İsmet; Kilis, Tuba
    Background and study aim: The aim of the present study was to investigate the effects of Lycium barbarum (LB) on bacterial translocation (BT) frequency in thioacetamide (TAA)-induced liver injury in rats. Materials and methods: Group 1 was the control. In group 2 (TAA), rats received TAA daily for 3 days. In group 3 (TAA+LB), Lycium barbarum was administered orally 25 mg/kg for 21 days prior to the first TAA injection. In group 4 (LB), rats received only Lycium barbarum. Results: In our study, Lycium barbarum treatment did not attenuate liver damage. Lycium barbarum treatment decreased ileal E. coli counts and intestinal damage but it did not alter BT frequency. Conclusions: In conclusion, the effects of Lycium barbarum on BT may be related to ongoing severe liver damage in this model.