Effects of Lycium barbarum on bacterial translocation in thioacetamide induced liver injury in rats
Yükleniyor...
Dosyalar
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
European Journal of Inflammation
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background and study aim: The aim of the present study was to investigate the effects of Lycium barbarum (LB) on
bacterial translocation (BT) frequency in thioacetamide (TAA)-induced liver injury in rats.
Materials and methods: Group 1 was the control. In group 2 (TAA), rats received TAA daily for 3 days. In group 3
(TAA+LB), Lycium barbarum was administered orally 25 mg/kg for 21 days prior to the first TAA injection. In group 4
(LB), rats received only Lycium barbarum.
Results: In our study, Lycium barbarum treatment did not attenuate liver damage. Lycium barbarum treatment decreased
ileal E. coli counts and intestinal damage but it did not alter BT frequency.
Conclusions: In conclusion, the effects of Lycium barbarum on BT may be related to ongoing severe liver damage in this
model.
Açıklama
Anahtar Kelimeler
Bacterial translocation, Liver injury, Lycium barbarum, Thioacetamide
Kaynak
European Journal of Inflammation
WoS Q Değeri
Scopus Q Değeri
Cilt
13
Sayı
3
Künye
Bilgiç, Y. Harputluoğlu, M. Kutlu, O. Demirel, U. Gül, M. Otlu, B. Temel, İ. Gürsoy, S. Dertli, R. Selçuk, E. B. Yılmaz, İ. Kilis, T. (2015). Effects of Lycium barbarum on bacterial translocation in thioacetamide induced liver injury in rats. European Journal of Inflammation, 13(3), 154–163.
