Effects of Lycium barbarum on bacterial translocation in thioacetamide induced liver injury in rats

dc.authorid101949en_US
dc.contributor.authorBilgiç, Yılmaz
dc.contributor.authorHarputluoğlu, Murat
dc.contributor.authorKutlu, O
dc.contributor.authorDemirel, Ulvi
dc.contributor.authorGül, Mehmet
dc.contributor.authorOtlu, Barış
dc.contributor.authorTemel, İsmail
dc.contributor.authorGürsoy, S.
dc.contributor.authorDertli, Ramazan
dc.contributor.authorSelçuk, Engin Burak
dc.contributor.authorYılmaz, İsmet
dc.contributor.authorKilis, Tuba
dc.date.accessioned2017-07-10T10:14:44Z
dc.date.available2017-07-10T10:14:44Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground and study aim: The aim of the present study was to investigate the effects of Lycium barbarum (LB) on bacterial translocation (BT) frequency in thioacetamide (TAA)-induced liver injury in rats. Materials and methods: Group 1 was the control. In group 2 (TAA), rats received TAA daily for 3 days. In group 3 (TAA+LB), Lycium barbarum was administered orally 25 mg/kg for 21 days prior to the first TAA injection. In group 4 (LB), rats received only Lycium barbarum. Results: In our study, Lycium barbarum treatment did not attenuate liver damage. Lycium barbarum treatment decreased ileal E. coli counts and intestinal damage but it did not alter BT frequency. Conclusions: In conclusion, the effects of Lycium barbarum on BT may be related to ongoing severe liver damage in this model.en_US
dc.identifier.citationBilgiç, Y. Harputluoğlu, M. Kutlu, O. Demirel, U. Gül, M. Otlu, B. Temel, İ. Gürsoy, S. Dertli, R. Selçuk, E. B. Yılmaz, İ. Kilis, T. (2015). Effects of Lycium barbarum on bacterial translocation in thioacetamide induced liver injury in rats. European Journal of Inflammation, 13(3), 154–163.en_US
dc.identifier.doi10.1177/1721727X15618413en_US
dc.identifier.endpage163en_US
dc.identifier.issn1721-727X
dc.identifier.issue3en_US
dc.identifier.startpage154en_US
dc.identifier.urihttp://eji.sagepub.com/lookup/doi/10.1177/1721727X15618413
dc.identifier.urihttps://hdl.handle.net/11616/7358
dc.identifier.volume13en_US
dc.language.isoenen_US
dc.publisherEuropean Journal of Inflammationen_US
dc.relation.ispartofEuropean Journal of Inflammationen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBacterial translocationen_US
dc.subjectLiver injuryen_US
dc.subjectLycium barbarumen_US
dc.subjectThioacetamideen_US
dc.titleEffects of Lycium barbarum on bacterial translocation in thioacetamide induced liver injury in ratsen_US
dc.typeArticleen_US

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