Yazar "Kaplan, Fatih" seçeneğine göre listele

Listeleniyor 1 - 16 / 16
  • Küçük Resim Yok
    Öğe
    Acute generalized exanthematous pustulosis due to Epstein-Barr virus infection in a neonate
    (Wiley, 2021) Kaplan, Fatih; Topal, Erdem
    Acute generalized exanthematous pustulosis (AGEP) is an uncommon inflammatory subcorneal pustular dermatosis typically caused by exposure to a medication. Several viral infections have also been implicated in its development. We describe herein a rare case of AGEP associated with acute Epstein-Barr virus (EBV) infection in a neonate.
  • Küçük Resim
    Öğe
    Aile hekimlerinin kistik fibrozis hastalığı, i?zlemi ve yenidoğan tarama testi konusundaki bilgi düzeyleri
    (2019) Demirtas, Mehmet Semih; Topal, Erdem; Kaplan, Fatih; Kılıç, Talat
    Öz: Giriş: Kistik fibrozis otozomal resesif geçen ve beyaz ırkta 1: 3000 doğum da bir görülen mortalitesi ve morbiditesi yüksek, kronik bir hastalıktır. Erken tanı, hastaların yaşam süresi ve kalitesini etkilemektedir. Türkiye’de, Ocak 2015 tarihi itibariyle kistik fibrozis yenidoğan tarama testi uygulanmaya başlanıldı. Bu çalışma; birinci basamakta çalışan aile hekimlerinin kistik fibrozis hastalığı ve kistik fibrozis yenidoğan tarama testi konusundaki bilgi düzeylerini ölçmeyi amaçlamıştır. Yöntem: Çalışmaya Malatya ilinde çalışan ve gönüllü olan toplam 115 aile hekimi dahil edilmiştir. Aile hekimleriyle yüz yüze görüşmeler araştırmacılar tarafından yapıldı ve KF hastalığıyla ilgili önceden hazırlanmış anket formu dolduruldu. Çalışma için Malatya ili Klinik Araştırmalar Etik Kurulu Başkanlığı’ndan onay alınmıştır. İstatistiksel değerlendirme SPSS (SPSS for Windows, Version 20.0, SPSS Inc, U.S.A) paket programı kullanılarak gerçekleştirildi. Bulgular: Aile hekimlerinin ortanca yaşı 42 (30-50) yaş olup, 65 (%56,5)’i erkek idi. Katılımcıların meslekteki ortanca süresi 17 yıl (5-25) idi. Aile hekimlerinin kistik fibrozis hastalığı konusundaki bilgi düzeylerine bakıldığında; 103 (% 89,6)’ü hastalığın otozomal resesif geçtiğini biliyordu. Kistik fibrozisi düşündüren belirtiler sorulduğunda; aile hekimlerinin %80,9’u büyüme geriliği ve %90,4’ü tekrarlayan akciğer enfeksiyonunun kistik fibrozisi düşündürdüğünü belirtti. Katılımcıların % 96,5’i kistik fibrozis tanısı için ter testi yapılması gerektiğini bilmelerine rağmen, ter testi pozitifliği için terdeki Cl konsantrasyonunun 60 mmol/L’nin üzerinde olması gerektiğini ancak %31,3’ü biliyordu. Katılımcıların %84,3’ü Türkiye’de yenidoğan döneminde kistik fibrozis tarama testinin yapıldığını biliyordu. KF testi pozitif çıkan hastaların kistik fibrozis merkezine gönderilmesi gerektiğini ise katılımcıların %62,6’sı doğru olarak cevapladı. Katılımcılara kistik fibrozisli hastaların izlemi konusundaki bilgileri sorulduğunda; sadece 21’i (%17,3) hastaların 3-6 ay aralarla kontrollere gitmeleri gerektiğini biliyordu. Katılımcıların sadece 39’u (%33,9) kistik fibrozisli hastaların düzenli göğüs fizyoterapisine devam etmeleri gerektiğini biliyordu. Sonuç: Birinci basamakta çalışan aile hekimlerinin kistik fibrozis hastalığı ve izlemi konusundaki bilgi düzeyleri yetersizdir. Bu nedenle Kistik fibrozis hastalığı için tıp fakültelerindeki mezuniyet öncesi eğitime ve mezuniyet sonrası mesleki eğitime önem verilmelidir.
  • Küçük Resim Yok
    Öğe
    The effect of nebulized magnesium sulfate on asthma attacks in the children
    (2023) Aslan, Mehmet; Cıtlak, Hilal Karabağ; Topal, Erdem; Bag, Harika G. Gozukara; Kaplan, Fatih
    Aim: This study aimed to determine the effect of adding nebulized magnesium sulfate to standard treatment in children with moderate to severe acute asthma attacks. Methods: Pediatric patients admitted to the emergency department with moderate to severe asthma attacks were included in the study. The patients were divided into two groups. Group S received standard treatment, while Group M received nebulized magnesium sulfate in addition to standard therapy. Results: A total of 129 patients were included in the study, 86 (66.7%) were male, and the median (minimum-maximum) age was 4 (2-8) years. When groups were compared, oxygen saturation at hour 1 was higher (p=0.024), and the PRAM (preschool respiratory assessment measure) scores at the 4th hour were lower (p=0.008) in the group that received magnesium sulfate. The groups had no differences regarding any of the other parameters at the 1st and 4th hours (p>0.05). Conclusion: Adding nebulized magnesium sulfate to standard treatment in children with asthma attacks improves oxygen saturation faster and positively affects PRAM score at hour 4.
  • Küçük Resim
    Öğe
    Evaluation of demographic data and laboratory of children receiving subcutaneous venom immunotherapy
    (2021) Topal, Erdem; Kaplan, Fatih
    Aim: Allergic reactions that develop after venom can be serious and fatal. The only treatment that can prevent these serious reactions is venom immunotherapy. Studies on venom immunotherapy in paediatric patients are limited. Aim of this study to evaluate the demographic data and laboratory results of paediatric patients who have received venom immunotherapy. Materials and Methods: The study included 45 patients who have received subcutaneous venom immunotherapy in Department of Paediatric Allergy and Immunology. Results: Thirty-three of the patients (73.3 %) were boys and 12 (26.7 %) were girls, the median age was 14 years (min.: 6, and max. 18). Apis mellifera venom was given to 24 (53.3 %) of 45 patients, and Guapes species venom immunotherapy was given to 21 (46.7 %) patients. While 15 (33.3 %) patients who received immunotherapy were living in Malatya, 30 patients were living in various provinces of the Eastern Anatolia region. While wide local reaction developed in 15 (33.3%) of the patients, systemic reaction developed in 3 (6.7 %) patients during venom immunotherapy. Apis mellifera prick test median diameter was determined as 4 mm and median of Apis specific Ig E value was determined as 6 kU/L. Guapes species prick test median diameter was determined as 4 mm and median of Guapes specific Ig E value was determined as 4 kU/L. Conclusion: Immunotherapy with Apis venom was more than Guapes venom in current study. Large local reaction was observed in 1/3 of the patients during immunotherapy. Therefore, attention should be paid in terms of systemic allergic reactions and large local reactions during immunotherapy. All necessary precautions should be taken during the immunotherapy.
  • Küçük Resim
    Öğe
    Evaluation of demographic data and laboratory of children receiving subcutaneous venom immunotherapy
    (2021) Topal, Erdem; Kaplan, Fatih
    Abstract: Aim: Allergic reactions that develop after venom can be serious and fatal. The only treatment that can prevent these serious reactions is venom immunotherapy. Studies on venom immunotherapy in paediatric patients are limited. Aim of this study to evaluate the demographic data and laboratory results of paediatric patients who have received venom immunotherapy. Materials and Methods: The study included 45 patients who have received subcutaneous venom immunotherapy in Department of Paediatric Allergy and Immunology. Results: Thirty-three of the patients (73.3 %) were boys and 12 (26.7 %) were girls, the median age was 14 years (min.: 6, and max. 18). Apis mellifera venom was given to 24 (53.3 %) of 45 patients, and Guapes species venom immunotherapy was given to 21 (46.7 %) patients. While 15 (33.3 %) patients who received immunotherapy were living in Malatya, 30 patients were living in various provinces of the Eastern Anatolia region. While wide local reaction developed in 15 (33.3%) of the patients, systemic reaction developed in 3 (6.7 %) patients during venom immunotherapy. Apis mellifera prick test median diameter was determined as 4 mm and median of Apis specific Ig E value was determined as 6 kU/L. Guapes species prick test median diameter was determined as 4 mm and median of Guapes specific Ig E value was determined as 4 kU/L. Conclusion: Immunotherapy with Apis venom was more than Guapes venom in current study. Large local reaction was observed in 1/3 of the patients during immunotherapy. Therefore, attention should be paid in terms of systemic allergic reactions and large local reactions during immunotherapy. All necessary precautions should be taken during the immunotherapy.
  • Küçük Resim Yok
    Öğe
    Experiences and attitudes of parents of children with cow's milk and other food-allergy
    (Codon Publications, 2022) Karakurt, Tuba; Bozkurt, Hayrunnisa Bekis; Kaplan, Fatih; Aksit, Anil; Cavkaytar, Ozlem; Topal, Erdem; Arga, Mustafa
    Introduction and objective: The attitude and behaviors of parents are important in the management of children with food allergy (FA). The aim of this study is to evaluate the experiences and attitudes of parents of children with allergy to cow's milk and other FA. Materials and methods: The parents of children with FA were asked to complete an 18-item questionnaire to evaluate the FA history and experiences during diagnosis, treatment, and follow up. Results: The data from 558 (91.2%) survey questionnaire that were filled completely were analyzed. The mean age of the parents was 33.4+4.9. It was found that most common food allergen was cow's milk (85.3%). The mean time to diagnosis from the onset of symptoms was 10.9 +/- 18.4 months. Around 229 parents (41.6%) admitted to at least four different physicians and 68 (12.3%) parents admitted to at least five different physicians before diagnosis. The median time to diagnosis from the onset of symptoms was five (1-108) months in the patients admitted to four or more physicians, but it was one (1.48) month in the patients that admitted to less physicians (p<0.001). The most common symptoms were dermatitis and mucus-bloody stool, the least common ones were cardiovascular symptoms. Only 21.1% of the patients were able to use hypoallergenic formulas (HAF) in accordance with the recommendation of the physician. Conclusions: Delayed diagnosis of FA is a major concern, and during this period the patients admit many physicians. A majority of the patients with CMPA experience difficulties while using HAFs, and only one-fifth of them is able to use formula regularly. (C) 2022 Codon Publications. Published by Codon Publications.
  • Küçük Resim
    Öğe
    Malatya'da Yaşayan 6-7 Yaş Grubu Çocuklarında Allerjik Hastalıkların Sıklığı ve İlişkili Risk Faktörleri
    (Astım Allerji İmmünoloji, 2017) Topal, Erdem; Kaplan, Fatih; Türker, Kenan; Kutlutürk, Kazım; Bağ Gözükara, Harika
    Öz: Giriş: Çocuklarda allerjik hastalıkların görülme sıklığı son yıllarda giderek artmaktadır. Malatya ilinde şu ana kadar allerjik hastalıkların sıklığını gösteren herhangi bir çalışma bulunmamaktadır. Çalışmadaki amacımız, Malatya ilinde 6-7 yaş arası çocuklardaki allerjik hastalıkların sıklığını ve ilişkili risk faktörlerini belirlemektir. Gereç ve Yöntem: Malatya ilinde, yaşları 6-7 arasında olan 480 çocuğa Türkçe'ye çevrilmiş "International Study of Asthma and Allergy in Childhood (ISAAC)" anketi uygulandı. Anketlerin 413'ü (%86) çocukların aileleri tarafından dolduruldu.Bulgular: Çocukların 210 (%50.8)'u erkek ve yaş ortalaması 6.6±0.49 idi. Çalışmamızda yaşam boyu hışıltı, rinit ve atopik egzama şikayetlerinin sıklığı sırasıyla; %20.3, %37, ve %7.5 idi. Son 12 aydaki sıklığı ise sırasıyla; %12.3, %32 ve %6.5 idi. Allerjik hastalıklar ile ilişkili risk faktörleri incelendiğinde, hışıltı ile ilişkili risk faktörleri; erkek cinsiyet (p=0.001), ebeveyn de astım öyküsü (p=0.002), çocukta doktor tanılı allerjik rinitin olması (p=0.025) ve evde hamam böceğinin görülmesi (p=0.002) idi. Rinit ile ilişkili risk faktörleri; öyküde doktor tanılı astımın (p<0.001) ve doktor tanılı atopik egzamanın olması (p=0.001) idi. Atopik egzama ile ilişkili risk faktörleri; ebeveyn de atopik egzama öyküsü (p<0.001) ve doktor tanılı astımın olması (p=0.006) idi. Sonuç: Çalışma, Malatya'da ISAAC anketi kullanılarak 6-7 yaş arası çocuklardaki allerjik hastalıkların sıklığını gösteren ilk çalışmadır. Çalışmamız Malatya'da yaşayan çocuklarda allerjik hastalık sıklığının düşük olmadığını göstermiştir.
  • Küçük Resim
    Öğe
    Nadir Bir Olgu: Kitle Şüphesi ile Başvuran ve Aktinomikoz Tanısı Alan Çocuk Hasta
    (2021) Guliyeva, Lale; Kaplan, Fatih; Topal, Erdem
    İnsan aktinomikozu, aktinomiçes cinsi bir bakterinin neden olduğu nadir görülen kronik bir enfeksiyondur. Travma, cerrahi operasyon öyküsü gibi mukozayı penetre edecek bir durum varlığında, mukozal bariyeri aşarak enfeksiyon oluşturabilir. Sağ omuzda ağrı ve şişlik, hâlsizlik ve öksürük şikâyeti ile 12,5 yaşındaki kız hasta kliniğimize başvurdu. Hastada, aktinomikoz hastalığı açısından herhangi bir risk faktörü olmamasına rağmen yapılan tetkiklerde aktinomiçes saptandı. Hasta, penisilin ile tedavi edildi. Bu olgu sunumunda, kitle ön tanısı ile gelip, aktinomikoz tanısı alan 12,5 yaşında kız hasta sunuldu.
  • Küçük Resim Yok
    Öğe
    Olfactory function, olfactory bulb volume, and quality of life after radiotherapy for nasopharyngeal cancer
    (Aves, 2021) Kaplan, Bilge Kurnaz; Kizilay, Ahmet; Kaplan, Fatih; Toplu, Yuksel
    Objective: Radiotherapy (RT) is the standard treatment for nasopharyngeal cancer (NPC). Various advers effects may occur after RT. In this study, we aimed to evaluate the advers effects of RT on the olfactory bulb and olfactory function in patients with NPC and describe the impact of these effects on the patients' quality of life. Methods: We investigated 21 patients with NPC who received RT at least 12 months earlier, in addition to 21 age- and sex-matched healthy controls. The participants underwent a detailed nasoendoscopic ear, nose, and throat examination. All participants received orthonasal olfaction tests and a nasopharyngeal magnetic resonance imaging scan to measure olfactory bulb volume; in addition, they filled out a quality of life questionnaire. Results: There was a significant difference between the orthonasal olfactory test results of the patients and controls (p<0.05). The left and right side olfactory bulb volume values of the patients and controls were statistically similar (p=0.07). There was a significant difference between the quality of life questionnaire results of the patients and controls (p<0.05). Conclusion: Olfactory dysfunction was present in the majority of patients with NPC who received RT.
  • Küçük Resim
    Öğe
    One of the causes of adenoid hypertrophy in preschool children, allergic rhinitis
    (2022) Kaplan, Fatih; Kurnaz, Bilge
    Adenoid hypertrophy is one of the most common causes of upper airway obstruction in childhood. Chronic inflammation around the adenoid tissue is thought to play an important role in adenoid hypertrophy. Allergic rhinitis is among these chronic inflammatory processes. Twenty-five-month-old male patient presented to otorhinolaryngology clinic with complaints of nasal obstruction, snoring, sleeping with mouth open at night and occasional shortness of breath while sleeping. His examination did not show any pathology other than pallor in the nasal mucosa. Adenoid vegetation/nasopharynx ratio was found to be 80% in the examination made by using fiberoptic nasopharyngolaryngoscope. Tonsillar grade was 1-2 hypertrophic in oropharyngeal examination. In the skin prick test, the patient was found to have grass pollen and tree pollen sensitivity. Nasal steroid and antihistaminic therapies were started. After treatment, the patient’s adenoid vegetation/nasopharynx ratio and complaints were found to decrease significantly.
  • Küçük Resim Yok
    Öğe
    One of the rare causes of recurrent otitis media: Bruton’s disease
    (2021) Kaplan, Bilge Kurmaz; Kaplan, Fatih
    Bruton’s disease is an X-linked immunodeficiency. Recurrent bacterial infections are seen in patients with this disease. A 2-year-old male patient was brought to the otolaryngology clinic due to pain in both ears and tenderness. It was learned from his anamnesis that he had recurrent otitis media and pneumonia attacks previously. Lymphadenopathy was not palpable in head and neck examination. Tonsillar tissue was small in oropharyngeal examination. It was learned that the patient’s parents were cousins; there were no other features in his family history. The patient, who had a history of recurrent sinopulmonary infections and whose parents were related, was re- ferred to pediatric immunology clinic with a pre-diagnosis of immunodeficiency. The patient was diagnosed with Bruton’s disease. Regular intravenous immunoglobulin treatment every three weeks was started. No new infection was observed in the follow-up.
  • Küçük Resim Yok
    Öğe
    Prevalence estimates of voiding disorders inTurkishschool-age children
    (Wiley, 2021) Kaplan, Fatih; Tabel, Yilmaz; Elmas, Ahmet Taner
    Objectives This study aims to investigate the prevalence of voiding disorders and identify the associated risk factors for school-age children in East Anatolia, Turkey. Methods We randomly selected six primary schools in Malatya in East Anatolia, and 907 students from 6 to 14 years old were involved. Data were obtained using the dysfunctional voiding and incontinence scoring system (DVISS) scale, and children who scored 8.5 or above on that scale were considered as having voiding disorders. Results Voiding disorders were detected in 175 (19.2%) of 907 children. One hundred and fifty-two (16.8%) had day-time urinary incontinence, and 131 (14.5%) had night-time incontinence. The findings showed a significant relationship between voiding disorder and daytime/night-time incontinence, and fecal incontinence. Voiding disorders decreased as the age increased. There was a significant relationship between voiding disorder and positive family history, and the quality of life of these children was significantly affected. Conclusion Voiding disorder is a common disease among school-age children. By identifying and treating voiding disorders and related risk factors in children in the early period, these children can be protected from possible medical or social complications.
  • Küçük Resim Yok
    Öğe
    The Prevalence of Allergic Diseases and Associated Risk Factors in the 6-7 Age Children Who are Living in Malatya, Turkey
    (Bilimsel Tip Yayinevi, 2017) Topal, Erdem; Kaplan, Fatih; Turker, Kenan; Kutluturk, Kazim; Gozukara Bag, Harika
    Objective: The prevalence of allergic disease in children has been increasing in the recent years. There is no previous study on the prevalence of allergic disease in Malatya, Turkey. We aimed to investigate the prevalence of allergic disease and related risk factors among children aged 6-7 years in Malatya. Materials and Methods: We administered the questionnaire of the International Study of Asthma and Allergies in Childhood (ISAAC) translated into the Turkish language to 480 children aged 6-7 years living in Malatya. The questionnaires were completed by the parents for 413 (86%) of the children. Results: There were 210 (50.8%) males and the overall mean age was 6.6 +/- 0.49 years. The lifetime prevalence of wheezing, rhinitis and eczema was 20.3%, 37% and 7.5% respectively and the reported prevalence for the last 12 months was 12.3%, 32% and 6.5% respectively. When the risk factors associated with allergic disease were analyzed; male gender (p=0.001), history of parental asthma (p=0.002), doctor's diagnosis of allergic rhinitis (p=0.025) and having cockroaches at the home (p=0.002) were associated with asthma. A history of doctor's diagnosis of asthma (p<0.001) and atopic eczema (p=0.001) were associated with rhinitis as risk factors. History of parental atopic eczema (p<0.001) and doctor's diagnosis of asthma (p=0.006) were associated with atopic eczema as risk factors. Conclusion: This study is the first to investigate the prevalence of allergic disease in the 6-7 years age group in Malatya using the ISAAC questionnaire. The current study shows the prevalence of allergic diseases is considerable in children living in Malatya.
  • Küçük Resim
    Öğe
    A rare case in an adolescent patient with nasal polyps resistant to polypectomy: Samter’s syndrome
    (2021) Kurnaz Kaplan, Bilge; Kaplan, Fatih
    The comorbidity of recurrent nasal polyps, non-steroidal anti-inflammatory drug hypersensitivity and chronic rhinosinusitis is called Samter’s syndrome. It is less common in childhood than in adulthood. Patients first have nasal symptoms and then asthma and non-steroidal anti-inflammatory drug (NSAID) hypersensitivity begin to accompany. For definitive diagnosis, NSAID or aspirin hypersensitivity must be shown with provocation test. In this case report, oral provocation test with ibuprofen was performed on a 17-year-old female patient who had recurrent nasal polyps and chronic rhinosinusitis accompanied by asthma and NSAID hypersensitivity and the test was found to be positive. The patient was diagnosed with Samter’s syndrome and aspirin desensitization was applied. Inhaled steroid, intranasal steroid and montelukast therapies were started. As a conclusion, although it is more common in adults, Samter’s syndrome should also be considered in pediatric patients with recurrent nasal polyp, chronic rhinosinusitis, asthma, and NSAID hypersensitivity.
  • Küçük Resim
    Öğe
    A rare case in an adolescent patient with nasal polyps resistant to polypectomy: Samter’s syndrome
    (2021) Kaplan, Fatih; Kurnaz Kaplan, Bilge
    Abstract: The comorbidity of recurrent nasal polyps, non-steroidal anti-inflammatory drug hypersensitivity and chronic rhinosinusitis is called Samter’s syndrome. It is less common in childhood than in adulthood. Patients first have nasal symptoms and then asthma and non-steroidal anti-inflammatory drug (NSAID) hypersensitivity begin to accompany. For definitive diagnosis, NSAID or aspirin hypersensitivity must be shown with provocation test. In this case report, oral provocation test with ibuprofen was performed on a 17-year-old female patient who had recurrent nasal polyps and chronic rhinosinusitis accompanied by asthma and NSAID hypersensitivity and the test was found to be positive. The patient was diagnosed with Samter’s syndrome and aspirin desensitization was applied. Inhaled steroid, intranasal steroid and montelukast therapies were started. As a conclusion, although it is more common in adults, Samter’s syndrome should also be considered in pediatric patients with recurrent nasal polyp, chronic rhinosinusitis, asthma, and NSAID hypersensitivity.
  • Küçük Resim Yok
    Öğe
    Successful desensitization protocol for pyridostigmine in a 12 year old patient with myasthenia gravis
    (Turkish J Pediatrics, 2023) Kaplan, Fatih; Topal, Erdem
    Background. Myasthenia gravis is a chronic, autoimmune disease with muscle weakness. Acetylcholinesterase inhibitors are used in the symptomatic treatment of the disease. Allergic reaction to pyridostigmine bromide is rare. In the literature, no allergic reaction to pyridostigmine bromide has been reported in the pediatric population. Case. A 12-year-old female patient diagnosed with myasthenia gravis consulted our clinic with the complaint of urticaria due to pyridostigmine bromide. The oral challenge test performed with pyridostigmine bromide was positive. As the patient was required to be continue pyridostigmine bromide with no suitable alternatives, it was decided that the patient had to be desensitized to pyridostigmine. During and after the desensitization protocol, no reaction was observed. Conclusions. In this report, a successful desensitization protocol for pyridostigmine bromide in a child with myasthenia gravis is discussed.