Successful desensitization protocol for pyridostigmine in a 12 year old patient with myasthenia gravis

Küçük Resim Yok

Tarih

2023

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Turkish J Pediatrics

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Background. Myasthenia gravis is a chronic, autoimmune disease with muscle weakness. Acetylcholinesterase inhibitors are used in the symptomatic treatment of the disease. Allergic reaction to pyridostigmine bromide is rare. In the literature, no allergic reaction to pyridostigmine bromide has been reported in the pediatric population. Case. A 12-year-old female patient diagnosed with myasthenia gravis consulted our clinic with the complaint of urticaria due to pyridostigmine bromide. The oral challenge test performed with pyridostigmine bromide was positive. As the patient was required to be continue pyridostigmine bromide with no suitable alternatives, it was decided that the patient had to be desensitized to pyridostigmine. During and after the desensitization protocol, no reaction was observed. Conclusions. In this report, a successful desensitization protocol for pyridostigmine bromide in a child with myasthenia gravis is discussed.

Açıklama

Anahtar Kelimeler

allergy, desensitization, myasthenia gravis, pyridostigmine bromide

Kaynak

Turkish Journal of Pediatrics

WoS Q Değeri

Q4

Scopus Q Değeri

Q3

Cilt

65

Sayı

2

Künye