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Öğe Acquired IgE-mediated food allergy after liver transplantation in children(Elsevier Espana Slu, 2015) Catal, F.; Topal, E.; Selimoglu, M. A.; Karabiber, H.; Baskiran, A.; Senbaba, E.; Varol, I.Background: In recent years, the number of studies regarding newly-diagnosed food allergies after liver transplantation has been increasing. In this study, we aimed to investigate the frequency, transplantation in children. Methods: Paediatric patients who underwent liver transplantation at Inonu University Faculty of Medicine, Organ Transplantation Institute were included in the study. Results: Forty-nine paediatric patients were enrolled in the study; 26 (53.1%) were female, the median age at transplantation was five years, and median follow-up time after transplantation was 16 months. Six patients (12.2%) developed IgE-mediated food allergies after transplantation; four had urticaria and/or angio-oedema and two developed anaphylaxis after food intake. Patients with and without IgE-mediated disease, immunosuppressant therapy with tacrolimus, and blood tacrolirnus level (p > 0.05 for each). Serum total IgE levels >= 100 IU/mL (p = 0.02) and peripheral eosinophilia (p = 0.026) were more common in the patients who developed IgE-mediated food allergies. In five of the six patients who developed IgE-mediated food allergies, reaction occurred within the first year after transplantation; the risk of developing a reaction was 2.7 times higher within the first year after transplantation than in subsequent years (95% CI, 1.546-4.914; p=0.026). No Epstein-Barr virus or cytomegalovirus infections were detected in any of the patients who developed IgE-mediated food allergies after liver transplantation. Conclusion: The risk of developing IgE-mediated food allergies is approximately three times higher within the first year after transplantation than in subsequent years. (C) 2014 SEICAP Published by Elsevier Espana, S.L.U. All rights reserved.Öğe BILATERAL SPLIT FEET: A NEW FINDING IN CORNELIA DE LANGE SYNDROME(Medecine Et Hygiene, 2010) Dogan, D. G.; Dogan, M.; Aslan, M.; Karabiber, H.Bilateral split feet: a new finding in Cornelia de Lange Syndrome: We report on a male infant with Cornelia de Lange syndrome and bilateral split feet. Bilateral split feet do not appear to have ever been a reported feature in any of the published cases of Cornelia de Lange syndrome.Öğe A COLLODION BABY WITH HYPOTHYROIDISM(Medecine Et Hygiene, 2010) Dogan, D. G.; Aslan, M.; Karabiber, H.A Collodion baby with hypothyroidism: Collodion baby is a rare keratinizing congenital disorder. Although it is milder in degree than harlequin fetus, the infant is at risk for increased water loss, thermal instability, percutaneous toxicity, and infection as a result of an impaired skin barrier function. Here we report on an 11 days-old collodion baby with hypernatremic dehydratation, septicemia and congenital hypothyroidism. To our knowledge congenital hypothyroidism associated with collodion baby is reported in only one case up to date.Öğe HALLERMANN-STREIFF SYNDROME WITH HEMIHYPERTROPHY(Medecine Et Hygiene, 2010) Dogan, D. G.; Karabiber, H.; Erhan, M. D.; Garipardic, M.; Davutoglu, M.; Guler, E.Hallerrnann-Streiff syndrome with hemihypertrophy: We report on a five year old girl with Hallermann-Streiff syndrome and hemihypertrophy. Hemihypertrophy does not appear to have ever been associated with Hallermann-Streiff syndrome.
