Yazar "Karabulut A.B." seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim Yok
    Öğe
    The effect of regular exercise and massage on oxidant and antioxidant parameters
    (Association of Physiologists and Pharmacologists of India, 2013) Karabulut A.B.; Emin Kafkas M.; Kafkas A.S.; Önal Y.; Kiran T.R.
    This experimental study aimed to determine the effects of the combined application of regular exercises and massage on the values of Malondialdehyde (MDA), Nitric Oxide (NOx), Glutathione (GSH), Adenosine Deaminase (ADA) and Superoxide Dismutase (SOD). Twenty five sedentary women (32-50 years) who did not have the habit of getting regularly massages or exercising and participated voluntarily in the study. The subjects were randomly separated into three groups: control group (CG, n=9), exercise group (EG, n=8), and massage and exercise group (MEG, n=8). The basic result of this study was that a statistically significant decrease was observed in the post-test MDA values of both EG and MEG subjects. Moreover, when the GSH and SOD values are compared to CG, a statistically significant increase was determined in the values of both EG and MEG. As a result, the findings show that regular physical activities and massage manipulations significantly decrease MDA, increase SOD and GSH activities, and result in no change in NOx and ADA activities supports the assumption that regular physical activity has positive health effects.
  • Küçük Resim Yok
    Öğe
    House dust-mites: Effect on antioxidant enzyme activities
    (2006) Karabulut A.B.; Atambay M.; Karaman U.; Kilic E.; Yazar S.; Saraymen R.; Daldal N.
    Background: House dust-mites are potent allergens of the indoor environment and are common inhabitants of houses worldwide. Free radicals are constantly produced by cells, mostly as reactive oxygen species. Once produced, free radicals are removed by antioxidant defenses, including the enzymes SOD, GPx, and CAT. Material/Methods: The aim was to describe the importance of the antioxidant enzymes SOD, GPx, and CAT co-acting in human cells against toxic reactive oxygen species and their relationship with pathophysiological processes in subjects who have dust-mites in their homes. Results: The activities of erythrocyte GPx and SOD in skin-test-positive (dust-mite-positive/negative) patients were significantly lower than those in dust-mite- and skin-test-negative controls (p<0.05). Among the skin-test-positive patients, SOD activity was found to be lower in dust-mite-positive than in dust-mite-negative patients (p<0.05). There was not a statistically significant difference between the CAT levels of skin-test-positive (dust-mite-positive/negative) patients and dust-mite- and skin-test-negative controls (p>0.05). Conclusions: This study clearly shows that dust-mite depresses the activities of SOD, GPx, and, to a small extent, CAT, which influence cellular reducing capacity and consequently may increase asthma risk more than other allergens. © Med Sci Monit, 2006.
  • Küçük Resim Yok
    Öğe
    Relationship between nitric oxide levels and delirium in patients with coronary bypass operation
    (2004) Sezer Ö.; Karlida? R.; Karabulut A.B.; Özcan C.; Nisano?lu V.; Türköz Y.; But A.
    Objective: Delirium is an acute brain failure which is related to various pathological conditions. Although there are some ideas about etiopathogenesis of delirium, some points have not been cleared yet. We aimed to investigate relationship between nitric oxide (NO) levels and delirium prospectively in patients with in coronary bypass operation. Methods: We included 50 (37 males, 13 females, ages: 37-75, mean±sd= 59.8±10.6) patients with coronary illnesses who will undergo bypass operation. Patients with dementia and any systemic disease, except hypertension and coronary artery disease, were excluded from study. Smoking was not allowed at least 7 days prior to operation. We diagnosed delirium using DSM-IV-TR (Diagnostic and Statistical Manual of Mental Disorders) criteria. Delirium Rating Scale was used to estimate delirium severity. Blood samples were taken pre-operationally and post operationally. Patients were divided into two groups as delirium group and nondelirium group. We compared the two groups according to NO levels. Results: 12 of the 50 patients had delirium. While there was no significant difference among blood NO levels pre-operationally between two groups, the NO levels were statistically higher in the delirium group than the nondelirium group. Conclusion: Our study is important since it is first study that investigated the relationship between NO and delirium. Blood NO levels become higher in patients who developed post operationally delirium. These findings can be explained by increased NO production in brain tissue due to increased cerebral ischemia and/or increased response to oxidative stress during operation.