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    Are refugees applying to child and adolescent psychiatry departments only to obtain a disability report? The experience of a department in a Turkish city on the Syrian border
    (2021) Karadag, Mehmet; Calisgan, Baran
    Aim: Children and adolescents are the most affected by wars. They are also at higher risk for psychiatric disorders. However, as in all disadvantaged groups, the reasons for applying to psychiatry departments in refugees may differ from the local population. So we aimed to investigate reasons for applying to psychiatry department, the sociodemographic characteristics, presence of psychopathologies, prescriptions and treatment compliance of child and adolescent Syrian refugees.Materials and Methods: This research comprises an outpatient clinical sample of 400 refugee patients. The data was obtained by retrospectively examining the records of Syrian refugee patients aged between 0 and 18 years old who applied to Mardin State Hospital Child and Adolescent Psychiatry Department between May 2018 and May 2019. The sociodemographic characteristics of the cases, their psychiatric diagnoses according to DSM-5, medicines, and their continuation to psychiatric controls were evaluated.Results: 59% (235) applied to the department for treatment of psychiatric symptoms and 41% (165) applied to obtain a disability report. The mean age of refugees included in the study was 8.1 ± 4.7, out of which 231 were boys (58%) and 169 were girls (42%). The two most common diagnoses were Intellectual Disabilities: n=46 (19%) and Trauma and Stressor Related Disorders: n=39 (17%). Only 27% of patients showed compliance with the offered treatment. The most used medications were antipsychotics (41.17%) and antidepressants (38.16%).Conclusion: In our sample psychopathology rates were high and treatment compliance was low. In addition, the application rate for the disability report was quite high. As a result protective and therapeutic strategies should be implemented to address these issues and awareness should be increased for psychiatric disorders.
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    Evaluation of Earthquake Victims Following the 2023 Kahramanmaras-Turkiye Earthquake: A Multicenter Trial with 8025 Cases
    (Galenos Publ House, 2025) Karakus, Ali; Avci, Akkan; Yesiloglu, Onder; Karadag, Mehmet; Avci, Begum Seyda; Kuvvetli, Adnan; Kaya, Adem
    Aim: Our multicenter study includes the largest number of earthquake victims reported in the literature, aiming to evaluate demographic data and outcomes of patients who presented to emergency departments following 2023 Kahramanmaras, Turkiye earthquake. Materials and Methods: Patients admitted to hospital emergency departments after the February 6, 2023 Kahramanmaras earthquakes were retrospectively evaluated over a 22-day period. Data analyzed included age, gender, triage scales, overall health status, vital signs, laboratory and imaging results, definitive diagnoses, outcomes of patients, and emergency interventions. Results: Of the 8025 patients reported in 18 centers, 51.2% (n=4112) were female, and the average age of the patients was 40.91 +/- 20.12. A total of 3578 people (57.6%) had a green triage tag, indicating good overall health with relatively minor injuries. Lower extremity fractures were the most prevalent finding in radiographs, accounting for 33.7% (n=663), of the cases, while cerebral hemorrhage, rib fractures, and lumbar fractures were the most common results in tomography scans. The three most common diagnoses were soft tissue trauma (n=1270; 21.1%), crush syndrome (n=932; 15.5%), and lower extremity fractures (n=851; 14.2%). Cast-splint application (n=813; 22.18%), central venous catheterization (n=393; 10.72%), and fasciotomy (n=322; 8.78%) were the primary procedures performed in the emergency departments. Out of the 1886 hospitalized patients, the orthopedics clinic received the highest number of admissions (n=600). A total of 3461 patients were discharged, and 495 died. Conclusion: Findings of our study revealed higher rates of morbidity and mortality than in previous earthquakes, with orthopedic injuries being the most common outcome of earthquake-related trauma. We believe that establishing tent hospitals in earthquake-prone regions and surrounding provinces, constructing long-term healthcare facilities and trauma centers with emergency services, testing facilities, imaging areas, operating rooms, hemodialysis and intensive care units, employing horizontal architecture designs, and improving referral networks can help to reduce these rates.
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    Evaluation of the effects of adipose-derived mesenchymal stem cells on intraperitoneal adhesions
    (Aves, buyukdere cad 105-9, mecıdıyekoy, sıslı, ıstanbul 34394, turkey, 2018) Uysal, Erdal; Dokur, Mehmet; Kirdak, Turkay; Kurt, Akif; Karadag, Mehmet
    Objectives: The goal was to examine the efficiency of local implementation of adipose-derived mesenchymal stem cells, which have an anti-inflammatory effect, in preventing the intra-abdominal adhesions in rats. Material and Methods: Twenty-one Wistar albino rats were randomly divided into 3 groups, 7 rats in each: Group 1 was defined as the control group, Group 2 as the sham group, and Group 3 as the adipose-derived mesenchymal stem cell group. A 6 cm mid-abdomen incision in the all the rats was performed. The cecum serosa and sub-serosa were injured by rubbing with a gauze. No agent was applied intraperitoneally for the rats in Group 1; 1.5 mL saline and 2x106/ kg allojenic adipose-derived mesenchymal stem cells in the 1.5 mL saline were injected into peritoneum of rats in Groups 2 and 3, respectively. Laparotomy was performed on the 14th day. Adhesion scores, histopathological examination, E-cadherin expression, and the tissue hydroxyproline level were evaluated. Results: The general adhesion score and collagen deposition in Group 3 were found to be significantly higher than in Groups 1 and 2 (p=0.003 and p=0.009, respectively). In the inflammatory cell comparison, a significant decrease was found in Group 3 in proportion to Groups 1 and 2 (p=0.001, p=0.005, respectively). The E-cadherin levels were found to be higher in Group 3 (p=0.003). Conclusion: Severe adhesion was observed in the adipose-derived mesenchymal stem cells group. Collagen intensity and E-Cadherin expression also increased in the adipose-derived mesenchymal stem cells group. The anti-inflammatory effect was also seen in the adipose-derived mesenchymal stem cells group.
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    Evaluation of the effects of adipose-derived mesenchymal stem cells on intraperitoneal adhesions
    (Aves, 2018) Uysal, Erdal; Dokur, Mehmet; Kirdak, Turkay; Kurt, Akif; Karadag, Mehmet
    Objectives: The goal was to examine the efficiency of local implementation of adipose-derived mesenchymal stem cells, which have an anti-inflammatory effect, in preventing the intra-abdominal adhesions in rats. Material and Methods: Twenty-one Wistar albino rats were randomly divided into 3 groups, 7 rats in each: Group 1 was defined as the control group, Group 2 as the sham group, and Group 3 as the adipose-derived mesenchymal stem cell group. A 6 cm mid-abdomen incision in the all the rats was performed. The cecum serosa and sub-serosa were injured by rubbing with a gauze. No agent was applied intraperitoneally for the rats in Group 1; 1.5 mL saline and 2x106/ kg allojenic adipose-derived mesenchymal stem cells in the 1.5 mL saline were injected into peritoneum of rats in Groups 2 and 3, respectively. Laparotomy was performed on the 14th day. Adhesion scores, histopathological examination, E-cadherin expression, and the tissue hydroxyproline level were evaluated. Results: The general adhesion score and collagen deposition in Group 3 were found to be significantly higher than in Groups 1 and 2 (p=0.003 and p=0.009, respectively). In the inflammatory cell comparison, a significant decrease was found in Group 3 in proportion to Groups 1 and 2 (p=0.001, p=0.005, respectively). The E-cadherin levels were found to be higher in Group 3 (p=0.003). Conclusion: Severe adhesion was observed in the adipose-derived mesenchymal stem cells group. Collagen intensity and E-Cadherin expression also increased in the adipose-derived mesenchymal stem cells group. The anti-inflammatory effect was also seen in the adipose-derived mesenchymal stem cells group.
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    Media-based clinical research on selfie-related injuries and deaths
    (Turkish Assoc Trauma Emergency Surgery, 2018) Dokur, Mehmet; Petekkaya, Emine; Karadag, Mehmet
    BACKGROUND: The incidence of taking selfies and sharing them on social media as well as selfie-related behaviors is increasing, particularly among young people, possible leading to selfie-related trauma. Therefore, we performed this clinical study to draw attention to selfie-related injuries and deaths. METHODS: We analyzed 159 selfie victims from 111 events or accidents, which were reported in the media sources. We evaluated vital results, demography, rhythmicity, preferences, event or accident types, selfie-related risk factors, affected body regions of victims with causes of injury, and death. RESULTS: We found that the majority of selfie victims were students. Selfie-related injuries and deaths were reported most frequently in India, the US, and Russia. The most preferred site of taking selfies was the edge of the cliff. The most frequently reported event or accident type was falling from a height. Mostly multiple body parts were affected in selfie-related injuries and deaths. The most frequent causes of selfie-related deaths were multitrauma and drowning. CONCLUSION: Selfie-related injuries and deaths have increased in the past years. Particularly, teenagers and young adults are at high risk for selfie-related traumas and deaths; therefore, drastic measures should be taken to reduce their incidence.