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Öğe Synthesis and Antimalarial Bioassay of Quinine - Peptide Conjugates(Wiley, 2013) Panda, Siva S.; Ibrahim, Mohamed A.; Kucukbay, Hasan; Meyers, Marvin J.; Sverdrup, Francis M.; El-Feky, Said A.; Katritzky, Alan R.Amino acid and peptide conjugates of quinine were synthesized using microwave irradiation in 52-95% yields using benzotriazole methodology. The majority of these conjugates retain in vitro antimalarial activity with IC50 values below 100nm, similar to quinine.