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Öğe The evaluation of chickenpox in the post-vaccination period in Turkey(2019) Bucak, Ibrahim Hakan; Almis, Habip; Kayak, Davut; Kilic, Fedli Emre; Geyik, Mehmet; Tekin, Mehmet; Konca, Capan; Turgut, MehmetKeywords: key.br /Mateial and Methods: Patients aged 0-17 years presented to Adiyaman University Training and Research Hospital Pediatrics clinics and diagnosed with chickenpox between January 2013 and December 2016 were included in the study. Data were analyzed on Statistical Package for the Social Sciences (SPSS, version 22.0, Chicago, IL, USA) software. p0.05 was regarded as statistically significant.br /Results: 314 patients diagnosed with chickenpox were included in the study. Mean age of the subjects included was 84.76 ± 41.67 months, and 54.1% were males and 46.9% females. A significant difference was observed between the groups in terms of age (p=0.001). Cases’ ages decreased on a year-by-year basis. Fifty (15.9%) cases of chickenpox were identified as having been infected despite vaccine. A significant difference was determined between the mean ages of vaccinated and non-vaccinated patients with chickenpox.br /Conclusion: Although the addition of a single dose chickenpox vaccine to the national immunization schedule in Turkey reduces both severe complication and the incidence of the disease. In the light of our study we think that the addition of a second dose of chickenpox vaccination to our routine vaccine schedule will further reduce hospitalization numbers resulting from chickenpox-related complications. More comprehensive studies on the subject are now needed.br / Chickenpox, Child, Varicella, Vaccine.Öğe Evaluation of factors associated with time to diabetic ketoacidosis resolution in children(Bayrakol Medical Publisher, 2022) Oztekin, Mehmet; Konca, Capan; Tekin, Mehmet; Bolu, SemihAim: In this study, it was aimed to examine the relationship between clinical, demographic, and laboratory characteristics of patients at admission and time to diabetic ketoacidosis (DKA) resolution. Material and Methods: The files of patients with the diagnosis of DKA between January 2013 and December 2018 were reviewed retrospectively.Results: A total of 25 patients were included in the study. The mean age of the patients was 9.3 +/- 3.41 years. In 19 patients (76%), diabetes mellitus (DM) was diagnosed simultaneously with DKA. The mean time to DKA resolution was found to be significantly longer among patients with a family history of DM, newly diagnosed DM, respiratory distress, odor of acetone on the breath, altered consciousness, and severe coma. There was a significant correlation between the time to DKA resolution and the Pediatric Risk of Mortality score and the length of stay. There was also a significant negative correlation between time to DKA resolution and both pH and HCO3 levels. Discussion: DKA is an acute, severe, and life-threatening complication of type 1 DM in children. It is important to identify the factors affecting the prognosis and resolution time of comas in these patients in order to predict outcomes. Our findings show that the prognosis will be worse and the time to resolution will be longer among children with altered consciousness, newly diagnosed DM, respiratory distress, a high PRISM score, severe DKA coma, and severe acidosis at the time of admission.Öğe Evaluation of Pediatric Delirium Awareness and Management in Pediatric Intensive Care Units in Turkey(Georg Thieme Verlag Kg, 2022) Konca, Capan; Anil, Ayse Berna; Kulluoglu, Emine Pinar; Luleyap, Doga; Anil, Murat; Tekin, MehmetDelirium has been associated with prolonged pediatric intensive care unit (PICU) stay and mechanical ventilation times as well as high hospital costs and mortality rates. This work aimed to examine pediatric delirium awareness and delirium management in Turkey. A total of 19 physicians responsible for their respective PICUs completed the survey. Most of the units (57.9%) did not use any assessment tool. Varying measures were applied in different units to reduce the prevalence of delirium. The number of units that continuously measured noise was very low (15.8%). Eye mask and earpiece usage rates were also very low. In pharmacological treatment, haloperidol, dexmedetomidine, benzodiazepines, and atypical antipsychotics were the most preferred options. Some units have reached a sufficient level of pediatric delirium awareness and management. However, insufficiencies in delirium awareness and management remain in general.Öğe Familial Mediterranean Fever in a Patient with PFAPA Syndrome(Galenos Yayincilik, 2015) Tekin, Mehmet; Konca, Capan; Gulyuz, Abdulgani; Toplu, YukselPeriodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome is one of the recurrent fever syndrome in childhood. Headache, abdominal pain, and joint pain can be seen in some patients, in addition to the classical signs. PFAPA attacks resolve with prednisolone. Membranous tonsillitis, lymphadenopathy, and occasionally aphthae were detected during each episode in a patient presenting with high fever, about 12 times until four years of age. All attacks were resolved completely with single-dose prednisolone in the patient, who was diagnosed with PFAPA syndrome. Genetic analysis was requested because of abdominal pain that was occasionally observed during attacks. Heterozygous mutation of M694V was detected through genetic investigation, and colchicine was initiated. The patient was diagnosed with familial Mediterranean fever (FMF) due to resolved abdominal pain and recurrent fever after colchicine therapy. It is known that some FMF patients benefit from prednisolone therapy. Therefore, other periodic fever syndromes should be excluded before the diagnosis of PFAPA and FMF should be considered in patients with PFAPA syndrome complaining of recurrent abdominal pain.Öğe The mean platelet volume levels in children with PFAPA syndrome(Elsevier Ireland Ltd, 2014) Tekin, Mehmet; Toplu, Yuksel; Kahramaner, Zelal; Erdemir, Aydin; Gulyuz, Abdulgani; Konca, Capan; Uckardes, FatihObjectives:. To assess whether mean platelet volume (MPV) can be used as a marker in the differential diagnosis of periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome. Methods: The leucocyte counts, thrombocyte counts, and MPV values of 57 children with PFAPA syndrome were recorded during an attack and an attack free period. These values were compared with a healthy control group of 55 individuals. Demographic features of the PFAPA patients group including age, gender and age of first attack, age at diagnosis, frequency of attacks, serum reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were also recorded. Results: The MPV values of the children with PFAPA both during an attack and attack free period were found significantly lower than the MPV values of healthy control group (p < 0.001). Also, the MPV values of the children with PFAPA during an attack were significantly lower than in attack free periods (p < 0.001). The MPV values showed no correlation with leucocytes counts, CRP, and ESR during attacks. A 8.30 fl [area under the curve (AUC: 0.965)] optimal cutoff value of MPV with a sensitivity of 89.5% and specificity of 92.8% was determined during an attack in children with PFAPA. Conclusions: The MPV values during an attack and attack free period of patients with PFAPA is lower than in controls. The MPV values may be used as a marker in the differential diagnosis of PFAPA syndrome but more studies are needed and they should be prospective in order to validate this data. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
