Yazar "Oguzturk, Hakan" seçeneğine göre listele
Listeleniyor 1 - 20 / 44
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Analysis of patients with upper gastrointestinal bleeding: a study from Anatolian, Turkey Seasonal Distribution of Gastrointestinal Bleeding(Drunpp-Sarajevo, 2012) Korkmaz, Ilhan; Eren, Sevki Hakan; Guven, Fatma Mutlu Kukul; Beydilli, Inan; Yildirim, Birdal; Oguzturk, HakanThe aim of our study was to analyze if we have a seasonal or circadian distribution of acute upper gastrointestinal bleeding (AUGIB) patients, and to evaluate the laboratory and demographic risk factors on mortality rates. We scanned all of the files of the patients who had been diagnosed with AUGIB, for a ten year period. Datas' about seasonal distribution, circadian rhythm, admission hemoglobin, blood urea nitrogen and demographic variables were extracted from the charts. We didn't observed a seasonal distribution for AUGIB inspite of we excluded the drug effect by analyzing its seasonal distribution. Also our patients were admitted mostly nights which was compatible with the literature. Whereas our admission rate between 24 and 06 hour period was low. Admission low hemoglobin level, impaired blood urea nitrogen and creatinine level, and patients with advanced age has a higher mortality rate (p=0.03, p=0.003, p=0.02, p=0.001 respectively). Climatic factors effect on the seasonal distribution among AUGIB patients is not observed. Other risk factors (mental-physical) should also be evaluated. Low hemoglobin level, impaired renal functions and advanced age are bad risk factors for prognosis.Öğe Antioxidative effects of curcumin, ?-myrcene and 1,8-cineole against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced oxidative stress in rats liver(Sage Publications Inc, 2011) Ciftci, Osman; Ozdemir, Ilknur; Tanyildizi, Sadettin; Yildiz, Sedat; Oguzturk, HakanThe aim of this study was to investigate the effectiveness of curcumin, beta-myrcene (myrcene) and 1,8-cineole (cineole) on antioxidant defense system in rats given a persistent environmental pollutant (2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD). Rats (n = 112) were divided randomly into 8 equal groups. One group was kept as control and given corn oil as carrier. TCDD was orally administered at the dose of 2 mu g/kg/week. Curcumin, myrcene and cineole were orally administered at the doses of 100 mg/kg/day, 200 mg/kg/day and 100 mg/kg/day, respectively, by gavages dissolved in corn oil with and without TCDD. The liver samples were taken from half of all rats on day 30 and from the remaining half on day 60 for the determination of thiobarbituric acid reactive substances (TBARS), reduced glutathione (GSH), catalase (CAT), glutathione peroxidase (GSH-Px) and CuZn-SOD levels by spectrophotometric method. The results indicated that although TCDD significantly (p <= 0.01) increased formation of TBARS, it caused a significant decline in the levels of GSH, CAT, GSH-Px and CuZn-SOD in rats. In contrast, curcumin, myrcene and cineole significantly increased GSH, CAT, GSH-Px and CuZn-SOD levels but decreased formation of TBARS. Additionally, the antioxidative effects of curcumin, myrcene and cineole were increased at day 60 compared to day 30. In the TCDD groups given curcumin, myrcene and cineole, oxidative stress decreased by time. In conclusion, curcumin, myrcene and cineole showed antioxidant activity and eliminated TCDD-induced oxidative stress in rats in a time-dependent manner.Öğe Apricot tree falls: a study from Malatya, Turkey(Allied Acad, 2016) Oguzturk, Hakan; Turgut, Kasim; Turtay, Muhammet Gokhan; Sarihan, M. Ediz; Gur, Ali; Beydilli, Inan; Gurbuz, SukruIntroduction: Falls from trees constitute an important and fatal form of injury. The present study aimed to assess the demographic and clinical features of apricot tree falls. Materials and methods: The patients who were admitted to the emergency department with a fall from an apricot tree between June 2015 and September 2015 were recorded prospectively. The age, gender, fall height, fall time, emergency department admission time, vital signs, injury types, treatments and outcomes, Glasgow coma score, and injury severity score, were studied for each patient. Results: There were 30 falls from apricot trees and all of them were male. The mean age was 29 +/- 18.9 years, and 33% of the patients were in the pediatric age group. The patients suffered from extremity (46.7%), spinal system (30%), chest (13.3%), abdomino-pelvic (6.7%), and head (3.3%) injuries. Arm and forearm fractures were ranked first among all the fractures. The majority of the patients (70%) were managed and discharged from emergency department. None of the patients died, and all of them recovered fully. Conclusion: Falls from apricot trees usually lead to only minor injuries. The emergency department has the most important role in the management of these injuries. A considerable amount of patients are children, therefore, clear and feasible rules regarding child workers will reduce falls from apricot trees.Öğe Atrial Fibrillation due to Blunt Cardiac Injury: Case Report(Aves, 2018) Turgut, Kasim; Yucel, Neslihan; Oguzturk, Hakan; Ulutas, Zeynep; Afsin, AbdulmecitIntroduction: Blunt cardiac injury secondary to chest trauma is an important cause of emergency department admissions. It can range from asymptomatic myocardial contusion to significant dysrhythmia, acute heart failure, valvular injury, or cardiac rupture. Case Report A 38-years-old patient was admitted to the emergency department with atrial fibrillation (AF) that occurred after a car accident. The patient had chest trauma caused by striking the steering wheel during the accident. The AF rhythm of the patient reverted to the normal sinus rhythm at the 3rd hour after trauma. Conclusion: Emergency medicine professionals should keep in mind arrhythmias due to blunt chest trauma and take electrocardiograms of patients to be able to provide treatment in time.Öğe Carotid Artery Dissection: A Case Report(Emergency Medicine Physicians Assoc Turkey, 2020) Ekmekyapar, Muhammed; Oguzturk, Hakan; Ekmekyapar, Tuba; Derya, Serdar; Gurbuz, SukruCarotid artery dissection, firstly described by Pratt-Thomas and Berger in 1947, typically begins in inner layer of artery wall, proceeds to the middle layer, and intramurally extends along length of the artery as a result of the pressure produced by blood stream. This study aims to report a case in which internal carotid artery dissection was diagnosed as secondary to trauma. A 24-year-old male patient was brought to the emergency room by 112 emergency service team after a motorcycle accident. Physical examination of the patient revealed a painful dermabrasion in his right neck region and other system examinations were normal. Carotid-vertebral color Doppler ultrasonography was performed on the patient because he had a right neck pain. Accordingly, an intimal flap appearance compatible with dissection was observed on the right internal carotid artery (ICA) proximal segment. Then, brain+cervical CT angiography was performed on the patient, and an appearance compatible with dissection was observed in the right ICA. Therefore, the patient was referred to neurology and neurosurgery consultation and accordingly admitted to neurosurgery intensive care unit. As a result, carotid artery dissection in addition to other intracranial pathologies should be considered among differential diagnoses for patients with head and/or neck pain complaints regardless of whether or not they have a trauma history.Öğe Chilaiditi syndrome: a rare cause of shortness of breath and abdominal pain(Aves, buyukdere cad 105-9, mecıdıyekoy, sıslı, ıstanbul 34394, turkey, 2018) Ekmekyapar, Muhammed; Turtay, Muhammet Gokhan; Yucel, Neslihan; Oguzturk, Hakan; Gurbuz, Sukru; Derya, SerdarIntroduction: Chilaiditi syndrome is a rare condition in which a segment of the small or large intestine is interposed in between the diaphragm and the liver. This case report presents a patient who was admitted to the Department of Emergency Medicine, Turgut Ozal Medical Center with complaints of respiratory distress and abdominal pain and then diagnosed with Chilaiditi syndrome. Case Report: An 81-year-old female patient was admitted to the emergency department with complaints of difficulty in breathing and abdominal pain. The patient's anamnesis indicated that difficulty of breathing increased when she had abdominal pain. There was no defense or rebound, but sensitivity was observed on abdominal examination. Other system examinations were normal. Abdominal ultrasonography performed on the patient was also normal. A dynamic thorax-abdominal tomography was obtained in terms of differential diagnosis of the patient who had abdominal pain. In the dynamic thorax-abdominal tomography of the patient, loops of the colon were visualized in the vicinity of the liver anterior segment, and these images indicated with Chiliaditi syndrome. Conclusion: As a result, when the causes of shortness of breath and abdominal pain are investigated, Chiliaditi syndrome should be considered as a differential diagnosis.Öğe Chilaiditi Syndrome: A Rare Cause of Shortness of Breath and Abdominal Pain(Aves, 2018) Ekmekyapar, Muhammed; Turtay, Muhammet Gokhan; Yucel, Neslihan; Oguzturk, Hakan; Gurbuz, Sukru; Derya, SerdarIntroduction: Chilaiditi syndrome is a rare condition in which a segment of the small or large intestine is interposed in between the diaphragm and the liver. This case report presents a patient who was admitted to the Department of Emergency Medicine, Turgut Ozal Medical Center with complaints of respiratory distress and abdominal pain and then diagnosed with Chilaiditi syndrome. Case Report: An 81-year-old female patient was admitted to the emergency department with complaints of difficulty in breathing and abdominal pain. The patient's anamnesis indicated that difficulty of breathing increased when she had abdominal pain. There was no defense or rebound, but sensitivity was observed on abdominal examination. Other system examinations were normal. Abdominal ultrasonography performed on the patient was also normal. A dynamic thorax-abdominal tomography was obtained in terms of differential diagnosis of the patient who had abdominal pain. In the dynamic thorax-abdominal tomography of the patient, loops of the colon were visualized in the vicinity of the liver anterior segment, and these images indicated with Chiliaditi syndrome. Conclusion: As a result, when the causes of shortness of breath and abdominal pain are investigated, Chiliaditi syndrome should be considered as a differential diagnosis.Öğe Clinical analysis of the cancer patients who admitted to the emergency room(Scientific Publishers India, 2016) Gurbuz, Sukru; Turtay, Muhammet Gokhan; Oguzturk, Hakan; Guven, Taner; Gur, Ali; Colak, Cemil; Durak, Mehmet AkifObjective: Patients with cancer diagnosis often admit to emergency room with complaints that are directly or indirectly related to their current condition. We aimed to analyze what complaints the cancer patients admit with most, how long the cancer patients who are treated with antitumor treatment admit to the emergency room after the antitumor treatment, which departments were consulted with these patients most and the outcomes of these patients in the emergency room. Method: In this study, 1946 male and female patients older than 18 years old with oncological diseases who admitted to the emergency room for any complaints were analyzed retrospectively. Results: 879 (45.2%) of the patients were females and 1067 (54.8%) of them were males. The mean age was 59.1. The most common complaint was abdominal pain with 344 (17.7%) patients. The most common malignancy was lung cancer with 335 (17.3%) patients. 610 (31.3%) of the patients in the study were still receiving chemotherapy whereas 1052 (54%) of the patients never had chemotherapy. 285 (14.6%) patients were not receiving chemotherapy although they previously had. It was found that the patients admitted to the emergency room a mean of 69.9 days after the chemotherapy. 651 (33.5%) of the patients were not consulted with any departments whereas other patients were consulted with other departments, with medical oncology being the most consulted department. 1017 (52.2%) patients were discharged from the emergency room and 895 (46%) patients were hospitalized. 33 patients (1.7%) died in the emergency room. Conclusions: Patients with lung cancer admitted to the emergency rooms more often. Cancer patients admitted to the emergency department with abdominal pain and shortness of breath most. Emergency physicians have increased responsibility for tests, treatment and hospitalization of these patients as the patients are generally older and have multiple conditions.Öğe COMPARISON OF PULMONARY FUNCTION TESTING AMONG NON-SMOKERS, HAND-ROLLED CIGARETTE SMOKERS AND FACTORY MADE CIGARETTE SMOKERS(Southeast Asian Ministers Educ Organization, 2018) Turgut, Kasim; Turtay, Muhammet Gokhan; Kilic, Talat; Oguzturk, Hakan; Gulacti, Umut; Gur, Ali; Guven, TanerTobacco use causes significant health problems. The aim of this study was to compare the following factors among factory-made cigarette (FMC) smokers, hand-rolled cigarette (HRC) smokers and non-smokers (NS): demographic characteristics, pulmonary function testing (PFT) and carboxyhemoglobin (COHb) levels. PFT included checking: forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC, forced expiratory flow from 25-75% of the vital capacity (FEF25-75) and peak expiratory flow (PEF). We wanted to determine the impact of smoking on pulmonary function testing and to determine any differences in PFTs and COHb levels between FMC and HRC smokers. A total of 182 participants (all males) were included in the study. The subjects in the study were randomly chosen from emergency service admissions which had complaints other than respiratory system. The mean age of study subjects was 40.8 (range: 22-92) years. Mean age of starting smoking among HRC smokers was not significantly different from FMC smokers (95% CI: -0.55-2.37, p=0.220). HRC smokers had significantly lower economic and education levels than FMC smokers (95% CI: 9.0-45.2, p<0.01). NS had highest economic and educational levels (95% CI: 35.9-66.6, p<0.01) of the 3 study groups. The mean [+/- standard deviation(SD)] FEV1/FVC was 76.66 (+/- 7.45) among FMC smokers (95% CI: 74.82-78.51), 77.36 (+/- 8.14) among HRC smokers (95% CI: 75.36-79.36) and 83.13 (+/- 5.08) among NS (95% CI: 81.70-84.56, p<0.01). The mean (+/- SD) FEV1 was 84.50 (+/- 17.80) among FMC smokers (95% CI: 80.12-88.92 ), 89.4 (+/- 15.8) among HRC smokers (95% CI: 85.56-93.32) and 95.30 (+/- 13.3) among NS (95% CI: 91.59-99.07, p<0.01). The mean (+/- SD) PEF was 81.90 (+/- 19.30) among HRC smokers (95% CI: 77.19-86.69), 78.10 (+/- 18.70) among FMC smokers (95% CI: 73.47-82.74) and 86.20 (+/- 16.0) among NS (95% CI: 81.70-90.69, p=0.06). The mean FVC, FEV1, FEV1/FVC, FEF25-75%, and PEF values among NS were significantly (p<0.05) higher for each variable than the mean of these values among FMC and HRC smokers. The mean COHb level among NS was significantly (p<0.05) lower than the mean COHb levels in the two smoking groups. There were no significant differences in PFT results or COHb levels between the two smoking groups (p>0.05). Cigarette smoking cause impairment of pulmonary function equally independent of the cigarette type (FMC, HRC) smoked.Öğe Comparıson of pulmonary functıon testıng among non-smokers, hand-rolledcıgarette smokers and factory made cıgarette smokers(Southeast asıan mınısters educ organızatıon, seameo-tropmed, 420-6 rajvıthı rd,, bangkok 10400, thaıland, 2018) Turgut, Kasim; Turtay, Muhammet Gokhan; Kilic, Talat; Oguzturk, Hakan; Gulacti, Umut; Gur, Ali; Guven, Taner; Colak, CemilTobacco use causes significant health problems. The aim of this study was to compare the following factors among factory-made cigarette (FMC) smokers, hand-rolled cigarette (HRC) smokers and non-smokers (NS): demographic characteristics, pulmonary function testing (PFT) and carboxyhemoglobin (COHb) levels. PFT included checking: forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC, forced expiratory flow from 25-75% of the vital capacity (FEF25-75) and peak expiratory flow (PEF). We wanted to determine the impact of smoking on pulmonary function testing and to determine any differences in PFTs and COHb levels between FMC and HRC smokers. A total of 182 participants (all males) were included in the study. The subjects in the study were randomly chosen from emergency service admissions which had complaints other than respiratory system. The mean age of study subjects was 40.8 (range: 22-92) years. Mean age of starting smoking among HRC smokers was not significantly different from FMC smokers (95% CI: -0.55-2.37, p=0.220). HRC smokers had significantly lower economic and education levels than FMC smokers (95% CI: 9.0-45.2, p<0.01). NS had highest economic and educational levels (95% CI: 35.9-66.6, p<0.01) of the 3 study groups. The mean [+/- standard deviation(SD)] FEV1/FVC was 76.66 (+/- 7.45) among FMC smokers (95% CI: 74.82-78.51), 77.36 (+/- 8.14) among HRC smokers (95% CI: 75.36-79.36) and 83.13 (+/- 5.08) among NS (95% CI: 81.70-84.56, p<0.01). The mean (+/- SD) FEV1 was 84.50 (+/- 17.80) among FMC smokers (95% CI: 80.12-88.92 ), 89.4 (+/- 15.8) among HRC smokers (95% CI: 85.56-93.32) and 95.30 (+/- 13.3) among NS (95% CI: 91.59-99.07, p<0.01). The mean (+/- SD) PEF was 81.90 (+/- 19.30) among HRC smokers (95% CI: 77.19-86.69), 78.10 (+/- 18.70) among FMC smokers (95% CI: 73.47-82.74) and 86.20 (+/- 16.0) among NS (95% CI: 81.70-90.69, p=0.06). The mean FVC, FEV1, FEV1/FVC, FEF25-75%, and PEF values among NS were significantly (p<0.05) higher for each variable than the mean of these values among FMC and HRC smokers. The mean COHb level among NS was significantly (p<0.05) lower than the mean COHb levels in the two smoking groups. There were no significant differences in PFT results or COHb levels between the two smoking groups (p>0.05). Cigarette smoking cause impairment of pulmonary function equally independent of the cigarette type (FMC, HRC) smoked.Öğe Cyclospora Oocysts and Entamoeba histolytica Adhesin Antigen Positivity in a Patient with Diarrhea: Case Report(Ortadogu Ad Pres & Publ Co, 2012) Oguzturk, Hakan; Kaya, Ozlem Aycan; Turtay, M. Gokhan; Atambay, MetinCyclospora cayetanesis is a pathogenic protozoan characterized with prolonged diarrhea in immunocompetent and immunocompromised patients. Despite its ubiqutous distribution, reports on this parasite from Turkey are scarce. Our case is a 28 years old patient, a nurse, who presented to the emergency department in June 2009 with diarrhea, nausea and vomiting during the last week. The stool specimen examination by Kinyoun's acid-fast stain revealed Cyclospora oocysts. Adhesin antigen of Entamoeba histolytica was also positive. The patient was treated with a combination of trimethoprim/sulfamethoxazole and omidazol and she fully recovered. The literature was reviewed and our case proved to be the first report on the coexistance of Cyclospora oocysts and Entamoeba histolytica adhesin antigen in a diarrheic patient. This case underlines the importance of screening for parasites in patients with diarrhea.Öğe Demographic features of acute drug poisoning admitted to Inonu University Hospital in Malatya, Turkey(Academic Journals, 2010) Oguzturk, Hakan; Turtay, Muhammet Gokhan; Pamukcu, Esra; Ciftci, OsmanIn this study, the patients appealed to Emergency Medicine Department, Faculty of Medicine, University of Inonu, Malatya, Turkey because the acute drug poisoning in the period from 01/01/2008 to 31/12/2009 were evaluated retrospectively. Demographic features of the patients, the agent responsible for poisoning and hospitalization rates were assessed. In this aim, we evaluated 178 patients, ages ranged from 18 to 77.79 (44.4%) were men and 99 (55.6%) patients were women. The mean ages of male and female were found to be 32.2 +/- 12.2 and 31.3 +/- 12.0, respectively. 91(51.1%) patients were living in rural areas and 87 patients (48.9%) were living in urban centers. It was found that 156 (87.6%) of these patients had first poisoning whilst 19 (10.7%) patients experienced second poisoning event and 3 (1.7%) patients had third poisoning event. The type of the poisoning was ingestion of drugs for suicidal intent in 146 (82%) cases and accidental ingestion in 32 (18%) cases. Poisoning most commonly occurred as ingestion of multiple drugs. Seven patients (3.9%) were discharged from the emergency service (ED), while 132 patients (74.2%) were hospitalized in intensive care unit of anesthesiology and 39 patients (21.9%) in the department of internal medicine. Average duration of hospitalization of all patients was 3.46 +/- 2.22 days. Drugs poisoning occur most frequently as ingestion of multiple drugs in young individuals and female.Öğe Detection of Entamoeba histolytica with different methods admitted to the emergency department in diarrheic patients(Academic Journals, 2011) Kaya, Ozlem Aycan; Oguzturk, Hakan; Turtay, Muhammet Gokhan; Daldal, U. NilgunAntigen screening were conducted to stool samples from 60 patients admitted to our emergency department with diarrhea complaint between June 2009 and October 2009 by the methods of direct microscopic examination, trichrome staining, ELISA (Enzyme-linked immunosorbent assay), respectively. As a result of examination of total 60 samples with direct microscopic, trichrome staining and ELISA method, it was detected positive in 7(11.3%), 6(9.7%) and 8(12.9%) samples, respectively. The presence of Entamoeba histolytica has been accepted exactly in the samples in which ELISA test results were positive and necessary treatment of patients has been started immediately. Due to precise pathogen protozoan discrimination has not been performed with the direct microscopic examination, it was emphasized that unnecessary drug therapy would be prevented as a result of detection of presence of E. histolytica specific antigen by ELISA in the samples sent to the laboratory with the diagnosis of amoebiasis by concerned physician.Öğe DOES 3-G MOBILE PHONE RADIOFREQUENCY AFFECT OXIDATIVE STRESS, SPERM CHARACTERISTICS AND TESTIS HISTOLOGY?(Parlar Scientific Publications (P S P), 2011) Oguzturk, Hakan; Beytur, Ali; Ciftci, Osman; Turtay, M. Gokhan; Samdanci, Emine; Dilek, Omer FarukThis study aims to investigate the effects of electromagnetic radiation (EMR) delivered by mobile phones on oxidative stress, histological damage and sperm characteristic in rats. For this purpose, 18 male rats (9 in the study group and 9 in the control group) were used. The rats in experimental group were exposed to EMR from an active (1.9-2.2 GHz) mobile phone (MP) for 20 min per day for 20 days. The rats in control group were exposed to an MP without a battery for the same period. The results showed that there was no significant differences in oxidative stress parameters (TBARS, GSH, SOD, CAT, GSH-Px), testis histology and reproductive organ weight (testis, epididymis, prostate weight) between the control and the study groups. On the other hand, it was observed that the use of MPs may have negative effects on the sperm characteristics (especially sperm motility) in rats. In conclusion, it was suggested that the exposure of EMR caused a decrease of fertility capacity due to their effects on sperm characteristics.Öğe THE EFFECT OF CHRONIC CARBON MONOXIDE EXPOSURE ON BRAIN IN BARBECUE WORKERS(Parlar Scientific Publications (P S P), 2014) Turtay, Muhammet Gokhan; Yumrutepe, Sevgi; Kahraman, Aysegul Sagir; Bentli, Recep; Oguzturk, Hakan; Firat, Cemal; Colak, CemilThe aim of our study is to investigate whether chronic carbon monoxide (CO) exposure has effects on the brains of the people who work as barbecue workers (BWs) for a long time. Twenty males who had been working in the indoor environments of various restaurants (Group I) and 20 healthy males who were matched by age with the other group (Group 2) were included in the study. Laboratory tests were performed in both groups of people. Magnetic Resonance Spectroscopy (MRS) was applied to the people whose blood samples were taken. In Group I, significant correlations were not detected between carboxyhemoglobin (COHb) values and the variables of age, working hours, hemoglobin (Hb), white blood cell (WBC), hematocrit (HCT), platelet (PLT), mean platelet volume (MPV), pH, oxygen saturation (Sat O2) (p>0.05). In terms of Hb, WBC, HCT, PLT, MPV, pH, Sat O2, COHb, N-acetylaspartate/creatine in basal ganglion, choline/creatine in basal ganglion, N-acetylaspartate/creatine in frontal lobe periventricular white matter, choline/creatine in frontal lobe periventricular white matter variables, significant differences between Group I and Group 2 were not determined. (p>0.05). As a result of this study; it is detected that chronic exposure to CO in BWs does not have any effects on brain with respect to MRS imaging method.Öğe Effect of renal colic analgesia on oxidative stress parameters(Academic Journals, 2010) Turtay, Muhammet Gokhan; Oguzturk, Hakan; Colak, Cemil; Polat, Alaadin; Tasdemir, CemalOur aim in this study is to investigate serum oxidative stress parameters before and after fentanyl analgesia in renal colic which is a severe pain condition and to reveal if there is correlation between fentanyl analgesia and serum oxidative stress parameters in renal colic pain. Thirty two male patients, aged 18 - 65, (mean age 40.7 +/- 14.9) who applied to our hospital with the complaint of flank pain and were diagnosed with renal colic were accepted to study. Blood samples were taken from the patients who were diagnosed with renal colic as a result of physical examination and tests (urine analysis, plain radiography, ultrasonography, computed tomography) Pain management of the patients was carried out. Fentanyl (50 - 150 mu g), an opioid analgesic, was used in all patients. When patients stated that the pain was definitely gone through, the blood samples were taken again. Blood samples were taken from each participant twice, before and after the analgesic. Malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) levels were measured from the blood taken. Statistical analysis of the levels which were obtained from before and after the fentanyl treatment was carried out. There were increases in CAT (P < 0.001), SOD (P = 0.002), MDA (P < 0.001), and GPx (P = 0.28) activities in response after analgesic administration in the patients. In our study, the treatment of renal colic pain with fentanyl, an opioid analgesic, led to significant increases in the levels of SOD and CAT, which are antioxidant enzymes.Öğe THE EFFECTS OF CHRYSIN ON BURN HEALING(Carbone Editore, 2021) Turtay, Muhammet Gokhan; Ciftci, Osman; Cetin, Asli; Gurbuz, Sukru; Oguzturk, Hakan; Basak, Nese; Firat, CemalIntroduction: This study aims to investigate the effects of chrysin on burn healing in burned model rats. Materials and methods: Rats were burned and randomly divided into four groups. Group 1; the group whose burn wound was left to secondary healing. Group 2; the group to which bacitracin neomycin sulfate pomade was topically administered. Group 3; the group to which chrysin was administered topically and with gastric gavage. Group 4; the group was assigned as the group to which chrysin and bacitracin neomycin sulfate was administered. Results: On days 3, 7 and 14, blood samples and skin biopsies were taken. Necrosis, congestion, hemorrhage and IL-1 beta were found to have the lowest levels on all days when bacitracin and chrysin were administered together. This group was also found to have the lowest level of TNF-alpha serum levels on days 7 and 14. Conclusion: We conclude that chrysin is effective in the treatment of burn wounds when used separately, but when combined with topical bacitracin pomade application, it is more effective for healing.Öğe Effects of montelukast on burn wound healing in a rat model(Canadian Soc Clinical Investigation, 2010) Turtay, Muhammet G.; Firat, Cemal; Samdanci, Emine; Oguzturk, Hakan; Erbatur, Serkan; Colak, CemilPurpose: Montelukast, a selective cysteinyl leukotriene D(4)-receptor antagonist, is used in the treatment of asthma. In a rat model, our aim was to investigate the effects of montelukast, alone or in combination with topical antibiotics, on local burn wound healing. Methods: Rats were randomly allocated to four groups after local burn development: Group 1; rats were left to secondary healing without treatment, Group 2; a dose of 10 mg/ kg montelukast was given by gastric gavage once a day for 10 days, Group 3; rats were treated with topical pomade (bacitracin neomycin sulphate), and Group 4; rats were treat with a combination of topical antibiotic and montelukast (10 mg/kg were given by gastric gavage once a day for 10 days). Skin biopsies were taken on days 3, 10, 14, and 20 relative to burn induction. Results: Reepithelialization in the pomade and montelukast+pomade groups on the 10(th) day was significantly greater, in comparison with control and montelukast groups (p<0.05). For the montelukast group, edema (on the 14(th) day) and angiogenesis, fibroblast proliferation, edema and macrophage infiltration (on the 20(th) day) were statistically improved in comparison with the control group (p<0.05). For the montelukast+pomade group, angiogenesis, fibroblast proliferation and macrophage infiltration (on the 10th day), and angiogenesis, fibroblast proliferation, edema and macrophage infiltration (on the 14th and 20th days) were statistically improved in comparison with the control group (p<0.05). Conclusion: In conclusion, montelukast was effective on burn wound healing. Moreover, the effect was amplified when combined with topical antibiotics applied in the early stage of burn wound healing.Öğe Electrical Injuries: The Demographical and Clinical Features(Galenos Yayincilik, 2010) Oguzturk, Hakan; Turtay, Muhammet Gokhan; Ertan, Cem; Akgun, Feride Sinem; Tekin, Yusuf KenanAim: Electrical injuries are an important health problem in our country, as well as worldwide. The aim of this study was to explore the demographic characteristics, complications and mortality associated with electrical injuries. Methods: In this study, 38 patients who had been exposed to electrical injuries and treated at the Emergency Department of, Faculty of Medicine, Inonu University between October 2008 and October 2010 were reviewed. Data pertaining to the patients were analysed retrospectively. Results: Out of 38 patients, 28 (73.7%) were male and 10 (26.3%) female. Electrical injuries were most frequently encountered in the 17-29 year age group, constituting 39.5% of cases. Eight (21.1%) patients were exposed to high voltage and 30 (78.9%) to low voltage. Among the circumstances leading to electrical injury, household accidents (63.2%) prevailed over the occupational accidents (36.8%). Two patients died due to sepsis. The overall mortality rate was 5.3 % and the mean hospital stay was 4.1 +/- 5.2 days. Conclusion: The results obtained from this research with respect to the demographic and clinical features can help the development of a particular strategy for electirical injuries.Öğe The Evaluation of Electrocardiogram Findings in Acute Abdominal Pain Patients Admitted to the Emergency Department(Sage Publications Inc, 2011) Oguzturk, Hakan; Turtay, Muhammet Gokhan; Tekin, Yusuf Kenan; Tekin, GulacanThe aim of this study was to determine the diagnostic value of electrocardiogram in differential diagnosis of patients with nonspecific abdominal pain. This prospective observational study was conducted in a university emergency department over 2 weeks. One hundred twenty patients with complaints of abdominal pain were admitted to the emergency department. During the study period, a total of 120 cases were evaluated. The final emergency department disposition status of the 120 patients was 1 (0.8%) died in the emergency department, 28 (23.3%) were admitted to the general ward, 27 (22.5%) were admitted to other services, and 10 (8.3%) were admitted to the cardiology service and coronary care unit. The examination indicated that 38 (31.7%) patients with abdominal pain showed cardiac pathologies on their electrocardiograms; 3 (2.5%) patients with abdominal pain admitted to cardiology service had ST elevation, and 2 (1.6%) had electrocardiogram depression on their electrocardiograms. According to the results, the authors claim that the electrocardiogram played an important role in the treatment and diagnosis of patients presenting with abdominal pain in emergency medicine. For this reason, it was thought that emergency medicine specialists should understand the basis of the perception of abdominal pain and develop a focused approach to the initial evaluation of these patients.
- «
- 1 (current)
- 2
- 3
- »
