THE EFFECTS OF CHRYSIN ON BURN HEALING

Küçük Resim Yok

Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Carbone Editore

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Introduction: This study aims to investigate the effects of chrysin on burn healing in burned model rats. Materials and methods: Rats were burned and randomly divided into four groups. Group 1; the group whose burn wound was left to secondary healing. Group 2; the group to which bacitracin neomycin sulfate pomade was topically administered. Group 3; the group to which chrysin was administered topically and with gastric gavage. Group 4; the group was assigned as the group to which chrysin and bacitracin neomycin sulfate was administered. Results: On days 3, 7 and 14, blood samples and skin biopsies were taken. Necrosis, congestion, hemorrhage and IL-1 beta were found to have the lowest levels on all days when bacitracin and chrysin were administered together. This group was also found to have the lowest level of TNF-alpha serum levels on days 7 and 14. Conclusion: We conclude that chrysin is effective in the treatment of burn wounds when used separately, but when combined with topical bacitracin pomade application, it is more effective for healing.

Açıklama

Anahtar Kelimeler

Chrysin, Bacitracin, Burn, Rat

Kaynak

Acta Medica Mediterranea

WoS Q Değeri

Q4

Scopus Q Değeri

N/A

Cilt

37

Sayı

2

Künye