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Öğe Amyloidosis cutis dyschromica: A case treated with acitretin(Wiley, 2005) Ozcan, A; Senol, M; Aydin, NE; Karaca, SWe report a case of amyloidosis cutis dyschromica with diffuse postinflammatory-type hypo- and hyperpigmentation all over the body. The diagnosis was confirmed with routine light microscopic and immunohistochemical staining methods. The patient was treated with acitretin with a good response.Öğe A case of Lupus vulgaris with unusual location(Japanese Dermatolgical Assoc, 2003) Senol, M; Ozcan, A; Mizrak, B; Turgut, AC; Karaca, S; Kocer, HTuberculosis (TB) is one of the oldest diseases of our planet; today, it still is a serious medicosocial problem in both developing and developed countries. Cutaneous tuberculosis is part of the small percentage of extrapulmonary forms of the disease and has considerable morphological variability. It is often confused with various cutaneous disorders and some other granulomatous processes of the skin. Here, we present a case of long-standing and atypically-located lupus vulgaris in an old man. The patient was successfully treated with triple antituberculous therapy.Öğe A case of sporotrichosis treated with itraconazole(Taylor & Francis Ltd, 2003) Ozcan, A; Senol, M; Karaca, S; Sener, S; Polat, M; Ozerol, IHLymphocutaneous sporotrichosis is caused by Sporothrix schenckii, a dimorphic fungus commonly existing on decaying plants and in the soil. The fungus has a worldwide distribution but is more prevalent in temperate and tropical climates. Infection may result from traumatic inoculation of contaminated material such as soil, hay, moss, plant debris, splinters, thorns and barbs. Inoculation is also possible through some animal scratches and bites. We describe a typical case of lymphocutaneous sporotrichosis, which was confirmed by clinical, histological and microbiological features. The patient was successfully treated with 400 mg daily systemic itraconazole for 4 months.Öğe Chronic effects of fluoride in Tuj sheep on serum levels of total protein, albumin, uric acid, and nitric oxide and activities of lactate dehydrogenase and leucine aminopeptidase(Int Soc Fluoride Research, 2005) Cenesiz, S; Ozcan, A; Kaya, N; Baysu, N; Karabulut, ABTwenty healthy yearling Tuj ewe-lambs with a mean body weight of 31 2 kg were divided into two equal groups. Each group of ten sheep was provided with hay and water ad libitum throughout the study. The water for the control group contained 0.49 mg F/L, whereas the water for the experimental group contained 13.8 mg F/L, equivalent for the latter group to an intake of ca. 1.8 mg F/kg bw/day. By the 12(th) week the urinary fluoride concentration in the experimental group had increased from 0.9 ppm at the start to 1.78 ppm, and by the 24(th) week it reached 8 ppm, at which point various serum determinations were made and the study was terminated. In the experimental vs. the control groups the results were as follows: total protein 7.41 +/- 0.03 vs. 7.67 +/- 0.07 g/dL (p<0.01), albumin 3.97 +/- 0.36 vs. 4.72 +/- 0.28 g/dL, nitric oxide 49.90 +/- 3.1 vs. 35.75 +/- 2.7 mu mol/L (p < 0.01), uric acid 0.49 +/- 0.03 vs. 0.29 +/- 0.02 mg/dL (p < 0.001), lactate dehydrogenase (LDH) 676.7 +/- 21 vs. 518 +/- 35 U/L (p < 0.01), and leucine aminopeptidase (LAP) 7.28 +/- 0.5 vs. 6.18 +/- 0.53 U/L. Changes in the albumin level and the LAP activity were not statistically significant. During and at the end of the study the urine fluoride concentration of the control group was unchanged.Öğe Disseminated lupus vulgaris and papulonecrotic tuberculid: Case report(Blackwell Science Inc, 2000) Senol, M; Ozcan, A; Aydin, A; Karincaoglu, Y; Sasmaz, S; Sener, SThe incidence of tuberculosis and extrapulmonary forms of this disease is increasing all over the world. Lupus vulgaris is the most prevalent form of cutaneous tuberculosis in Europe and the Middle East, Papulonecrotic tuberculid, the most common form of hyperergic response to mycobacteria or their fragments, is uncommon in children. We report lupus vulgaris with papulonecrotic tuberculid in a 12-year-old girl who had a 3-year history of slowly growing plaques on her trunk, extremities, and the tip of her nose and papuloulcerative lesions over her entire body. A skin biopsy specimen showed minimally caseating granulomatous inflammation, Staining for acid-fast bacilli was negative in both plaques and papules. Polymerase chain reaction identified Mycobacterium tuberculosis DNA in the patient's sputum, gastric fluid, and plaques and was negative in the papules. She was started on antituberculous therapy with four drugs and her lesions responded rapidly.Öğe Embolia cutis medicamentosa (Nicolau syndrome) two cases due to different drugs in distinct age groups(Adis Int Ltd, 2005) Ozcan, A; Senol, M; Aydin, EN; Aki, T[Abstract Not Available]Öğe Fox-Fordyce disease(European Acad Dermatology & Venereology, 2003) Ozcan, A; Senol, M; Aydin, NE; Karaca, S; Sener, S[Abstract Not Available]Öğe Giant vascular eccrine spiradenoma(Blackwell Science Ltd, 1998) Senol, M; Ozcan, A; Sasmaz, S; Ozen, S; Ciralik, HA 60-year-old man suffering from cardiac insufficiency consulted the Dermatology Department, Inonu University Turgut Ozal Medical Center, because of a bleeding tumor on his right hypochondrium. The tumor had begun as a small nodule approximately 5 years before, and had grown slowly with time. A small, superficial ulcer had appeared on the lesion approximately 6 months previously, and slight bleeding had occasionally occurred. The patient had no pain and no other complaint except bleeding. Dermatologic examination revealed a violaceous, ulcerated, and bleeding tumoral lesion below the mid-portion of the right costochondral line (Fig. 1). The tumor was a non-tender, hemispheric mass, approximately 3-4 cm in size, adherent to the epidermis, but movable on the underlying tissue. An incisional biopsy was performed with diagnoses of dermatofibrosarcoma protuberans and desmoid tumor. Histopathologic examination revealed prominent blood-filled vascular spaces (Fig. 2) and clearly delimited cords, showing two types of cell (Fig. 3). The vascular spaces contained a periodic acid-Schiff (PAS)-positive, granular, eosinophilic material. There was no malignant transformation. The lesion was totally excised and primarily sutured.Öğe Pityriasis rosea-like eruption due to lithium(Adis International Ltd, 2004) Senol, M; Ozcan, A; Ozcan, EM; Aydin, EN[Abstract Not Available]Öğe The risk of coronary heart disease in men with androgenetic alopecia(Elsevier Science Bv, 1999) Sasmaz, S; Senol, M; Ozcan, A; Dogan, G; Tuncer, C; Akyol, O; Sener, SBackground The meaningful association of androgenetic alopecia and coronary heart disease has been well documented, but few studies have focused on the importance of lipid parameters, such as total cholesterol, triglycerides, high density lipoprotein-cholesterol, low density lipoprotein-cholesterol, lipoprotein (a), apolipoprotein A1 and apolipoprotein B in patients with androgenetic alopecia. Objective The aim of this study is to investigate the relation between androgenetic alopecia and coronary heart disease and to determine the significance of certain lipid parameters on this relationship. Subjects Forty-one men with vertex type androgenetic alopecia (study group) and 36 men, age-matched, with normal hair status (control group) were the subjects of this study. Results We found significant differences in serum lipoprotein (a) and triglyceride levels between the study and control groups (P < 0,05). Forty-seven percent of patients and 30% of controls had a lipoprotein (a) level more than 30 mg/dl higher than the level critical for atherosclerotic heart disease. Conclusion Dermatologists should investigate lipid profile, especially lipoprotein (a), of patients with androgenetic alopecia and refer to a cardiologist if necessary. (C) 1999 Elsevier Science B.V. All rights reserved.
