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Öğe The Association of Serum Vitamin D Levels with Pseudoexfoliation Glaucoma/Syndrome (vol 19, pg 166, 2019)(Bentham Science Publ Ltd, 2019) Dikci, Seyhan; Ozturk, Emrah; Firat, Penpe Gul; Yilmaz, Turgut; Taskapan, Mehmet Cagatay; Yologlu, Saim[Abstract Not Available]Öğe Canalicular Incisional Approach for Recanalization of Punctum: A Modified Surgical Treatment for Acquired Complete Upper and Lower Punctum Occlusions as an Alternative to Bypass Methods(Lippincott Williams & Wilkins, 2020) Demirel, Soner; Ozturk, Emrah; Dikci, Seyhan; Firat, Penpe GulPurpose: To define the success of surgical technique used in the treatment of epiphora that is caused by bi-canalicular acquired complete punctum occlusion. Materials and Methods: The study is a retrospective consecutive case series, who underwent canalicular incisional approach for recanalization (CIAFOR) for acquired bi-canalicular punctum occlusions. The authors have used this technique in the cases not possible to perform a punctum dilatation and not possible to determine the punctum location exactly due to severe fibrosis. Functional and anatomical success was evaluated by the absence of epiphora and with lavage at post-operative 6th months. Results: Seven eyes of 5 patients (3 males and 2 females) were included in the study. The ages of the patients were 70, 65, 45, 64, and 70 years, respectively. Current follow-up periods vary between 6 and 23 months. Although functional and anatomical success achieved in all eyes, complication such as accessory punctum observed. Conclusions: CIAFOR seems to be a successful and simple surgical technique to treat acquired total punctum occlusion.Öğe Chorioretinal dystrophy, hypogonadotropic hypogonadism, and cerebellar ataxia: Boucher-Neuhauser syndrome due to a homozygous (c.3524C>G (p.Ser1175Cys)) variant in PNPLA6 gene(Taylor & Francis Inc, 2021) Dogan, Mustafa; Eroz, Recep; Ozturk, EmrahPurpose: The current study aims to raise awareness of Boucher - Neuhauser syndrome (BNHS) that occurs as a rare phenotype due to biallelic pathogenic variants in the PNPLA6 gene. Methods: Detailed family histories and clinical data were recorded. Whole exome sequencing was performed and co-segregation analysis of the family was done by sanger sequencing. Also, review of 28 molecularly confirmed patients with BNHS from the literature was evaluated. Results: We identified a missense homozygous variant (c.3524 C > G (p.Ser1175Cys)) in the PNPLA6 gene, which explains the phenotype of the patient and neurologic, ophthalmologic, endocrine, and genetic evaluations established a diagnosis of BNHS. Symptoms, ethnicity, clinical and genetic findings of 28 molecularly confirmed patients with BNHS from the literature were also presented. Conclusion: We present the main findings of a Turkish family with BNHS together with detailed clinical and genetic profiles of patients diagnosed as BNHS that have been molecularly confirmed in the literature so far.Öğe Correlation between intraocular pressure obtained with water drinking test versus modified diurnal tension curve measurement in pseudoexfoliation glaucoma(Springer, 2021) Firat, Penpe Gul; Dikci, Seyhan; Firat, Ilknur Tuncer; Demirel, Soner; Firat, Murat; Ozturk, Emrah; Gok, Zarife EkiciPurpose The aim of this paper was to study the correlation and agreement between the intraocular pressure (IOP) peak value and fluctuations detected with the modified diurnal tension curve (mDTC) and the water drinking test (WDT) in pseudoexfoliation glaucoma (XFG) patients. Methods This prospective observational study enrolled 42 eyes of 42 XFG patients. The IOPs were measured at 2-h intervals from 8 am to 4 pm with a Goldmann applanation tonometer by a single observer to establish the mDTC. The WDT was then performed between 4 and 5 pm on the same day and the IOP was measured 4 times at 15-min intervals after water ingestion. The IOPpeak, IOPmean, IO (min), and IOPfluctuation were measured with both the mDTC and WDT. The paired sample t test, Spearman's correlation coefficient and Bland-Altman plots were used for statistical analysis. Results The mean age of the 42 patients consisting of 24 females and 18 males was 66.9 +/- 6.8 years, and the mean central corneal thickness was 517.7 +/- 29.1 mu m. The mean values with the mDTC and WDT measurements were 15.05 +/- 2.75 mmHg and 17.17 +/- 3.25 mmHg (p <= 0.0001, r = 0.884) for IOPmean, 16.76 +/- 3.45 mmHg and 18.92 +/- 3.94 mmHg (p <= 0.0001, r=0.787) for IOPpeak, and 13.61 +/- 2.56 mmHg and 15.11 +/- 2.84 mmHg (p <= 0.0001, r=0.824) for IOPmin, respectively, and a positive correlation was present between these values. Conclusion There was a positive correlation between the peak, minimum, and mean IOP values determined using the mDTC and WDT in treated XFG patients. WDT can be used as an alternative in the assessment of the IOP in these patients as a more practical method.Öğe Double Flip Technique for Graft Transfer in Autograft Pterygium Surgery(Galenos Publ House, 2023) Ozturk, Emrah; Gunduz, AbuzerA 50-year-old man with recurrent pterygium and a 46-year-old woman with primary pterygium underwent surgery using a novel autograft transfer technique that facilitates autograft suturing and ensures correct graft orientation. After removing the pterygium, three edges of the autograft were cut. The autograft was flipped first over the uncut edge and secured to the superior margin of the recipient bed with two sutures. Afterward, the fourth side of the graft was cut and the second flip was done over the sutured edge. Thus, the autograft was in correct surface and side orientation and was sutured to the recipient bed. This simple technique provides both easy transfer and correct orientation of the graft in autograft pterygium surgery.Öğe Effect of Vitamin D Deficiency on Contrast Sensitivity Function(Taylor & Francis Inc, 2020) Ozturk, Emrah; Cankaya, CemPurpose The purpose of this study is to investigate the effects of vitamin D (vit D) deficiency on contrast sensitivity (CS) function and retinal layers. Materials and methods Group 1 consisted of 42 patients aged between 18 and 50 years with vit D deficiency and Group 2 consisted of sex- and age-matched 34 healthy subjects with normal vit D levels. Functional acuity contrast testing (FACT) was performed using the Optec 6500 vision testing system. The average retinal nerve fiber layer (RNFL) thickness and macular thickness (MT) obtained from nine macular areas in the Early Treatment Diabetic Retinopathy Study were evaluated using SD-OCT (RS-3000; Nidek Inc., Fremont, CA, USA) following a detailed ophthalmologic examination. Measurements were performed on both eyes. Results A lower CS was found in Group 1 compared to Group 2 in all spatial frequencies. A statistically significant difference was observed between the groups in 6, 12 and 18 cpd spatial frequencies, respectively. (p = .004, p = .001, p = .042, respectively). There was no statistically significant difference between groups in terms of RNFL thicknesses (p = .200). There was an increase in MT in Group 1. However, this increase was statistically significant in the inferior inner area in the right eye, and in the inferior inner, temporal inner and outer macular areas in the left eye (p = .018, p = .003, p = .033, p = .040, respectively). Conclusion It was observed that vit D deficiency had negative effects on CS function and also caused thickness difference in certain segments of retinal layers.Öğe Evaluation of the equality of medial rectus advancement to medial rectus resection for consecutive exotropia(Cukurova Univ, Fac Medicine, 2022) Gunduz, Abuzer; Ozturk, Emrah; Ozsoy, ErcanPurpose: The aim of this study was to analyze the amount of medial rectus (MR) advancement in the treatment of consecutive exotropia by comparing it with the amount of MR resection in a sample of patients with constant exotropia and evaluate the effectiveness of MR advancement with lateral rectus (LR) recession in the management of consecutive exotropia. Materials and Methods: A retrospective chart review of patients who underwent unilateral MR strengthening with LR weakening due to consecutive or constant exotropia was performed. Patients with consecutive exotropia underwent MR advancement with LR recession, and those with constant exotropia underwent MR resection with LR recession. The surgical dosages were determined according to a standard table. A successful result was defined as alignment within 10 prism diopters of orthotropia. Results: A total of 36 patients fulfilled the inclusion criteria: 18 had consecutive exotropia and 18 had constant exotropia. Successful alignment was obtained in 83.3% of patients with consecutive exotropia and 88.9% of patients with constant exotropia. There was no difference between the amount of MR advancement performed in consecutive patients with exotropia and the amount of MR resection performed in patients with constant exotropia. Postoperatively, while consecutive exotropes with a poor result showed overcorrection, constant exotropes with a poor result showed undercorrection. Conclusion: This study suggests that there is no difference between the amount of previously recessed MR advancement and that of untouched MR resection. They also showed that MR advancement with LR recession is an effective means of correcting secondary exotropia.Öğe The Impact of COVID-19 on Conjunctival Flora(Taylor & Francis Inc, 2021) Gunduz, Ayten; Ozturk, Emrah; Cagasar, OzlemPurpose: This study aims to evaluate the effect of coronavirus disease 2019 (COVID-19) on conjunctival flora in patients hospitalized with COVID-19. Methods: This prospective, controlled study was conducted between June 2020 and December 2020. The study group consisted of 45 confirmed COVID-19 patients and 43 control subjects. The collected samples were inoculated into the Thioglycollate broth media without delay. The samples with growth were then passed on eosin methylene blue agar, sabouraud dextrose agar, chocolate agar, and 5% sheep blood agar solid media. Results: The mean age of the COVID-19 patients was 64.24 +/- 15.4 years, and the control subjects were 59.72 +/- 11.4 years. The culture positivity of conjunctiva samples in COVID-19 patients (95.6%) was statistically significantly higher than control subjects (76.7%) (p = .024). Coagulase-negative staphylococcus and Staphylococcus aureus' positivity was significantly higher in COVID-19 patients than control subjects (p < .05). Conclusion: Patients with COVID-19 demonstrate significantly higher culture positivity on conjunctival flora than the control subjects.Öğe Infantile Esotropia: Clinical Features and Results of Bilateral Medial Rectus Recession(Galenos Publ House, 2023) Gunduz, Abuzer; Ozturk, Emrah; Ozsoy, Ercan; Gunturkun, Pelin NazliIntroduction: To define the characteristics of infantile esotropia and evaluate the results of bilateral medial rectus recession in infantile esotropia. Methods: A retrospective review was performed on medical charts of patients diagnosed with infantile esotropia. All patients underwent an ophthalmological examination to detect the conditions that accompany infantile esotropia. Patients with two years of age or older and without fixation preference or amblyopia underwent bilateral medial rectus recession. Results: There were a total of 117 patients with infantile esotropia patients. Infantile esotropia was accompanied by inferior oblique hyperfunction, fixation preference, cross-fixation, pseudoabduction deficit, pattern deviations, nystagmus, dissociated vertical deviation, convergence insufficiency, and abnormal head position. Approximately forty percent of the patients compatible with visual acuity measurements had amblyopia. Bilateral medial rectus recession decreased the mean esotropia from 43.1 +/- 15.3 to 7.8 +/- 12.8 prism diopters (PD) in 65 patients. Postoperatively, 41 patients had an ocular alignment within 10 PD of orthotropia, 22 patients showed undercorrection and 2 overcorrection. Conclusion: The characteristics of infantile esotropia in our study are substantially consistent with those of early reports, except for convergence insufficiency. This study also showed that bilateral medial rectus recession appears to have a high percentage of undercorrection in short-term postoperative follow-up in infantile esotropia.Öğe Inferior oblique anterior transposition according to a different grading scale for hyperdeviation with inferior oblique overaction(Canadian Ophthal Soc, 2023) Gunduz, Abuzer; Ozturk, Emrah; Firat, MuratObjective: To define an inferior oblique anterior transposition (IOAT) grading scale in patients with hyperdeviation and inferior oblique overaction (IOOA), which we planned based on the data we obtained in our previous retrospective study.Participants: Thirty-eight patients who underwent graded IOAT.Methods: The patients were divided into 5 groups according to the amount of hyperdeviation in the primary position (PPHD). The inferior oblique muscle was transposed 2 mm posterior, 1 mm posterior parallel, 1 mm anterior, and 2 mm anterior to the inferior rectus insertion, respectively. Surgical success was defined as success (PPHD <= 3 PD), partial success (PPHD >3 and <= 6 PD), and nonsuccess (PPHD >6 PD).Results: The mean amount of hyperdeviation correction in groups after IOAT was 9.50 +/- 0.9 PD (range, 8-10 PD), 12.43 +/- 1.5 PD (range, 11-14 PD), 16.67 +/- 1.4 PD (range, 15-18 PD), 19.57 +/- 1.7 PD (range, 16-21 PD), and 22.57 +/- 5.8 PD (range, 14-30 PD), respectively. Surgical success was achieved in 34 patients (89.5%) after surgery, partial success was achieved in 3 patients (7.9%), and nonsuccess was observed in 1 patient (2.6%). All patients in our study had unilateral IOOA preoperatively, and IOOA developed in the contralateral eye of 9 patients (23.7%) during postoperative follow-up. In group 5, 4 patients (57.1%) developed -2 upgaze limitation, but surgery was not required.Conclusions: A high success rate can be achieved with this grading of IOAT in primary and secondary IOOA cases accompanying hyperdeviation in the primary position.Öğe Inferior Oblique Muscle Overaction: Clinical Features and Surgical Management(Hindawi Ltd, 2019) Ozsoy, Ercan; Gunduz, Abuzer; Ozturk, EmrahPurpose. To further define the clinical features of patients with inferior oblique muscle overaction (IOOA) and evaluate the surgical results in a subgroup of these patients. Methods. The medical records of 173 patients who underwent inferior oblique muscle (IO) weakening surgery due to primary or secondary IOOA were retrospectively reviewed. The patients were assigned a surgical group based on severity of IOOA and presence of dissociated vertical deviation (DVD) or hypertropia. Patients with +1 or +2 IOOA underwent recession, patients with +3 or +4 IOOA underwent myectomy, and patients with any grade of IOOA and DVD or hypertropia underwent anterior transposition (AT) surgery. Results. A total of 286 eyes of 173 patients who underwent surgery due to IOOA were included in the study. IOOA was accompanied by esotropia, exotropia, abnormal head posture (AHP), pattern strabismus, convergence insufficiency, DVD, facial asymmetry, and nystagmus. The most common comorbid disorder was esotropia. The recession was used in 173 eyes, myectomy in 64, and AT in 49. Surgical success was obtained in 96.0% of eyes that underwent recession, in 98.4% of eyes that underwent myectomy, and in 93.9% of eyes that underwent AT. In the follow-up, IOOA occurred in the fellow eye in 36.1% of patients who underwent unilateral surgery. Conclusions. This study is a comprehensive report on the concomitants of the IOOA. Also, it showed that all of the three surgical procedures including recession, myectomy, and AT are effective in the surgical management of IOOA when performed in select patient groups.Öğe Long-term effects of phacoemulsification surgery on intraocular pressure in patients with primary open-angle glaucoma and pseudoexfoliation glaucoma(2020) Ozturk, Emrah; Firat, Penpe GulOzturk, E., & Gul Firat, P. (2021). Long-term effects of phacoemulsification surgery on intraocular pressure in patients with primary open-angle glaucoma and pseudoexfoliation glaucoma . Annals of Medical Research,Öğe Optimal timing of capsular tension ring implantation in pseudoexfoliation syndrome(Consel Brasil Oftalmologia, 2021) Ozturk, Emrah; Gunduz, AbuzerPurpose: The aim of this study was to evaluate the appropriate timing of capsular tension ring implantation in cases of zonular weakness due to pseudoexfoliation syndrome. Methods: This prospective, comparative study was performed at the Ophthalmology Department of Inonu University, Malatya, Turkey. There were 43 patients included in the study. Group 1 ( 16 patients) had early capsular tension ring implantation, and group 2 (27 patients) had late capsular tension ring implantation. Patients with pseudoexfoliation syndrome who underwent phacoemulsification surgery, posterior chamber intraocular lens implantation, and capsular tension ring implantation were included in the study. Intraoperative complications and difficulties with either capsular tension ring implantation or cortex removal were evaluated in each eye. Results: There was no significant difference between the groups in the difficulty of capsular tension ring implantation (p=0.124). The difficulty of cortex removal differed significantly between the groups (p=0.003). Intraoperative complications were observed in 3 patients in group 1 and 11 patients in group 2; the difference between the groups was not significant (p=0.18). Posterior capsule fluctuations were observed in 8 patients (29.5%) in group 2, which resulted in posterior capsule rupture in 2 patients. Conclusions: Cortex removal is more difficult with early capsular tension ring implantation, and posterior capsule fluctuations may cause problems with late capsular tension ring implantation. The surgeon must consider the risk-to-benefit ratio of early versus late insertion for the optimal timing of capsular tension ring implantation.Öğe Pre-, intra- and post-operative management in phacoemulsification surgery for completely monocular cases(2019) Demirel, Soner; Dikci, Seyhan; Firat, Penpe Gul; Ozturk, Emrah; Ceylan, Osman Melih; Turkoglu, Elif Betul; Yilmaz, Turgut; Gunduz, Abuzer; Gozukara Bag, Harika GozdeAim: To evaluate the results of phacoemulsification (PE) surgery in completely monocular cases and to emphasize the important points in the pre-, intra- and post-operative periods. Material and Methods: A total of 42 patients who had no light perception in one eye and had underwent PE surgery in the other eye at our clinic between January 2014 and March 2016 were included in the study. The charts of the patients were evaluated retrospectively. The age and gender of the cases, whether there was an additional pathology in the eye undergoing surgery, the reason of visual loss in the other eye, the type of anesthesia used, pre- and post-operative best corrected visual acuity (BCVA) with the Snellen chart, intraocular pressure and intra- and post-operative complications were investigated. Results: There were17 (40.5%) female and 25 (59.5%) male patients with a mean age of 74.2±10.5 (45-93) years. The most common causes of the monocular state were glaucoma, cataract and trauma, the most common accompanying pathologies in the eyes undergoing cataract surgery were glaucoma, zonular weakness and age-related macular degeneration. Mean BCVA was 0.07±0.1 (0.01-0.4) pre-operatively and 0.5±0.3 (0.01-1) post-operatively (p≤0.001). The mean follow-up duration was 3.9±5.6 months (1 week to 24 months). The most common post-operative complication was corneal edema. Conclusion: The stress created by cataract surgery on the physician and patient is quite high in monocular cases. However, satisfactory results with PE are obtained in these cases by carefully using pre-, intra- and post-operative methods.
