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Öğe The effect of abdominal surgery on serum CA-125 levels(2000) Sari R.; Camci C.; Sevinc A.; Demirbilek O.; Ertas E.; Buyukberber S.[No abstract available]Öğe The effects of abdominal and bimanual pelvic examination and transvaginal ultrasonography on serum CA-125 levels(2000) Sari R.; Buyukberber S.; Sevinc A.; Ates M.; Balat O.; Hascalik S.; Turk M.The need for the early detection of ovarian cancer continues to be one of the most important issues in women's health care. The three most extensively evaluated screening methods for ovarian cancer are pelvic examination, transvaginal ultrasonography, and serum CA-125 levels. The answers to questions such as should the levels of CA-125 be measured before bimanual pelvic examination or transvaginal ultrasonography or do abdominal examinations effect the levels of CA-125 are obscure. Fifty-four otherwise healthy female volunteers at the preovulatory phase of the menstrual cycle complaining of vaginal candidiasis were divided into 3 groups. Abdominal (group 1), bimanual pelvic (group 2), and transvaginal ultrasonography (group 3) examination was performed and serum CA-125 levels were evaluated prior to examination and 10 minutes, 6 hours, and 24 hours after the examination. As a result, serum CA-125 levels (U/ml) were found to be 8.13 ± 4.76, 8.23 ± 5.05, 8.32 ± 4.88, and 8.33 ± 4.94 in the group of abdominal examination, respectively, 8.23 ± 4.89, 8.45 ± 5.15, 8.77 ± 4.96, and 8.79 ± 5.50 in the group of bimanual pelvic examination, respectively, and 8.19 ± 4.56, 8.30 ± 5.10, 8.81 ± 5.56, and 8.88 ± 5.71 in the group of transvaginal ultrasonography, respectively. The serum CA-125 levels detected prior to examinations were statistically insignificant when compared with the results obtained at 10 minutes, 6 hours, and 24 hours later in all three groups. We concluded that physical examination, either abdominal or pelvic, and transvaginal ultrasonography do not change the serum levels of CA-125.Öğe Gluten-free Diet Improves Iron-deficiency Anaemia in Patients with Coeliac Disease(2000) Sari R.; Yildirim B.; Sevinc A.; Buyukberber S.Two cases of newly-diagnosed asymptomatic coeliac disease with 3 years of unexplained severe iron-deficiency anaemia are presented. Oral iron supplementation had no effect on their serum iron levels and, therefore, had no influence on their anaemia. Upper gastrointestinal endoscopy confirmed normal macroscopic findings. Duodenal biopsies revealed subtotal villous atrophy of the mucosa of the small intestine. A strict gluten-free diet led to an increase in serum iron, resolution of anaemia, and restitution of normal mucosal morphology. Thus, severe iron-deficiency anaemia associated with asymptomatic coeliac disease is responsible to gluten-free diet.Öğe Idiopathic hypoparathyroidism and celiac disease in two patients with previous history of cataract.(2000) Sari R.; Yildirim B.; Sevinc A.; Buyukberber S.We report two patients with idiopathic hypoparathyroidism and celiac disease. Both had undergone surgery for cataract previously. The patients presented with tetany in the absence of gastrointestinal complaints. Investigations showed severe hypocalcemia, hypoparathyroidism, flattening of duodenal villi histologically, and diffuse cerebral and basal ganglia calcifications on CT scan. After a gluten-free diet with calcium supplementation, the clinical situation and biochemical values improved.Öğe The prevalence of lymphoid follicles and intestinal metaplasia in Helicobacter pylori associated clinically significant gastroduodenal diseases(Turkish Society of Gastroenterology, 1999) Taskin V.; Gurer I.; Sari R.; Aydin A.; Yildirim B.; Aladag M.; Hilmioglu F.This study was designed to investigate the prevalence of lymphoid follicle formation and intestinal metaplasia in patients with Helicobacter pylori (H.pylori) associated clinically significant diseases. Biopsies from the antrum, corpus and fundus of stomach were obtained from 153 patients (non-ulcer dyspepsia, n:110; duodenal ulcer n:23, duodenal ulcer complicated by obstruction, n:20) with histopathologically proven H. pylori infection. All biopsies were examined for lymphoid follicle with germinal center and intestinal metaplasia. Lymphoid follicles were found in 44.5% of non-ulcer disypeptic patients, 70% of duodenal ulcer complicated by obstruction patients and in 47.8% of uncomplicated duodenal ulcer patients. In contrast, 15.5% of non-ulcer disypeptic patients and 20% of complicated duodenal ulcer patients had associated intestinal metaplasia while no intestinal metaplasia was observed in uncomplicated duodenal ulcer patients. Intestinal metaplasia incidence was not statistically different among the different gastroduodenal pathologies (P>0.05). However the incidence of lymphoid follicles was significantly higher in patients with complicated duodenal ulcer (P<0.05). Our results indicate that H.pylori infection in complicated duodenal ulcers are relatively chronic and aggressive compared to H.pylori infection in other gastroduodenal disorders.Öğe Re. Zuckerman et al. - Sensitivity of Ca-125 in patients with liver cirrhosis in the presence of ascites [5](Elsevier Inc., 2001) Sari R.[No abstract available]Öğe A secondary interpretation is needed on serum CA 125 levels in case of serosal involvement (multiple letters)(2000) Sevinc A.; Sari R.; Carnei C.; Buyukberber S.; Ahmed A.S.M.; Long M.; Donaldson D.[No abstract available]Öğe Synchronous primary malignant neoplasms of colon and bladder.(2001) Sari R.; Buyukberber S.; Sevinc A.; Mizrak B.Extracolonic and synchronous malignancies are rare in colorectal carcinomas. We report a 68-year-old man with complaints of rectal bleeding and hematuria. Endoscopic biopsies revealed synchronous adenocarcinoma of the colon and transitional cell carcinoma of the bladder. The patient was started on chemotherapy, and is alive (with disease) nine months later.
