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Öğe Acute and chronic effects of electroconvulsive treatment on oxidative parameters in schizophrenia patients(Pergamon-Elsevier Science Ltd, 2011) Kartalci, Sukru; Karabulut, Aysun Bay; Ozcan, Abdul Cemal; Porgali, Esra; Unal, SuheylaElectroconvulsive therapy (ECT) is an effective treatment alternative for schizophrenia. Previous studies have already indicated the possible effects of oxidative stress in this disorder. However, there have been no previous studies evaluating the effects of ECT on the oxidative stress in these patients. We therefore aimed to investigate the acute and chronic effects of ECT on serum levels of oxidant and antioxidant molecules in schizophrenia patients (n = 28). The serum MDA and CAT levels of the patients with schizophrenia were higher than that of the controls before ECT (n = 20) but there was no significant difference in the serum NO and GSH levels of the patient groups compared to the controls. We found that the NO levels of the patients were higher than the controls in the group experiencing their first episode but not in the chronic group. There was a significant clinical improvement in the patients in terms of BPRS. SANS and SAPS reduction after the 9th ECT, but not the 1st ECT. Serum MDA levels were significantly reduced compared to the baseline after the 9th ECT session although there was no significant difference after the 1st session. Separate evaluation of the patient groups revealed that the significant MDA decrease following ECT was in the patients experiencing their first episode and not in the chronic group. No significant difference was noted in the serum levels of other oxidant and antioxidant molecules after either the 1st or 9th ECT session. These results suggest that ECT does not produce any negative effect on oxidative stress in patients with schizophrenia. (C) 2011 Elsevier Inc. All rights reserved.Öğe Analysis of posttraumatic embitterment disorders by machine learning: Could sullenness be a predictor of posttraumatic embitterment disorder?(Kare Publ, 2022) Kilic, Bahar; Karakaplan, Mustafa; Unal, SuheylaObjective: This study aimed to determine some fundamental factors specific to posttraumatic embitterment disorder (PTED) using deep machine learning (ML) and network analysis techniques. Method: Sociodemographic data form, Buss-Perry Aggression Questionnaire, Brief Symptom Inventory (BSI), PTED Self-Rating Scale (PTED Scale), and list of stressful life events were administered to 557 people who applied to the outpatient anxiety clinic. ML method and network analysis were applied with the 33 most significant variables. Results: PIED was found in urban areas (p=0.006), individual health problems (p=0.029), early separation from their families (p=0.040), previous trauma (p=0.021), describing childhood sexual abuse (p<0.001), and those with the illness for more than 10 years (p<0.001) were detected at a higher rate than those without. The PIED score was higher in those with an anxiety disorder (p=0.043) and a personality disorder (p<0.001). Almost all life stressors were higher in the PIED group. There was a statistically significant difference between the groups in all subscales of the BSI. When the ML procedure was applied, sullenness was identified as the main symptom of PIED. The factors most associated with sullenness were well-being, hopelessness, and painful event experience. Conclusion: The higher rate of chronic trauma in the group with PTED and the detection of sullenness as the main symptom have been important data for understanding the psychopathological process.Öğe Association between latent toxoplasmosis and clinical course of schizophrenia - continuous course of the disease is characteristic for Toxoplasma gondii-infected patients(Folia Parasitologica, 2015) Celik, Tuncay; Kartalci, Sukru; Aytas, Ozgur; Akarsu, Gulay Aral; Gozukara, Harika; Unal, SuheylaThe aim of the present study was to investigate the association between various clinical aspects of schizophrenia and seropositivity against Toxoplasma gondii (Nicolle et Manceaux, 1908). We selected 94 patients with schizophrenia and investigated the seropositivity rate for anti-T. gondii IgG antibodies by ELISA. Clinical parameters of schizophrenic patients such as illness type and status, clinical course, awareness of the illness and need for electroconvulsive therapy (ECT) were compared with their serological status. Anti-T. gondii IgG antibodies were detected in 43 (46%) of schizophrenic patients. Chronic patients had a rate of 34 (72%) seropositivity, whereas 9 (22%) of the patients with partial remission showed evidence of latent toxoplasmosis. Of continuous patients, 35 (81%) were found to be seropositive and this rate was significantly more than in the other groups. The rate of latent toxoplasmosis was detected significantly higher in patients who lack awareness of schizophrenia (36, i.e. 72%) than the patients who were aware of their illnesses (7, i.e. 16%). Anti-T. gondii IgG antibodies were detected in 38 (70%) of ECT performed patients while this percentage was 13% in the ones who had never been treated with ECT. This difference was also statistically significant. We showed that Toxoplasma-infected subjects had 15x higher probability of having continuous course of disease than Toxoplasma-free subjects. Our results put forth the possibility of latent toxoplasmosis to have a negative impact on the course of schizophrenia and treatment response of schizophrenic patients.Öğe Attachment and Psychopathology: Relationship between Adult Attachment and Depression, Panic Disorder, and Obsessive Compulsive Disorder(Turkish Psychologists Assoc, 2009) Sumer, Nebi; Unal, Suheyla; Selcuk, Emre; Kaya, Burhanettin; Polat, Ruhcan; Cekem, BuelentThe objective of this study was to investigate the relationship between adult attachment dimensions and different types of psychopathologies. One hundred and four individuals who were diagnosed with depression, obsessive-compulsive disorder, or panic disorder; and 77 individuals who were not diagnosed with a psychopathology (i.e., control group) participated in the study. Participants completed self-report measures of adult attachment. All three disorder groups reported higher attachment anxiety as compared to the control group. Moreover, patients diagnosed with depression reported higher avoidant attachment as compared to the other disorder groups. A discriminant function analysis was conducted to test if adult attachment dimensions discriminate among different disorder groups and the control group. First function, which was defined by attachment anxiety, discriminated the control group from the three psychopathology groups and the second function, which was defined by attachment avoidance, discriminated the depression group from the other groups. These findings indicate that high attachment anxiety and avoidance emerge as risk factors to develop psychopathology. Possible mechanisms mediating the link between adult attachment and psychopathology are discussed in light of findings of the current study and cultural factors.Öğe Attachment styles in women with vaginismus(Cumhurıyet unıv tıp fak psıkıyatrı anabılım dalı, cumhurıyet unıv tıp fak psıkıyatrı abd, sıvas, 58140, turkey, 2015) Ozcan, Ozlem; Elbozan Cumurcu, Birgul; Karlidag, Rifat; Unal, Suheyla; Aktan Mutlu, Elif; Kartalci, SukruObjective: Attachment styles reflect individual differences in beliefs about oneself and others, interpersonal functioning and close relationships. This study intended to investigate attachment styles of vaginismus patients. Methods: Our sample was included 56 patients with vaginismus and 51 healthy women. Golombok Rust Inventory of Sexual Satisfaction Scale (GRISS) and Relationship Scales Questionnaire (RSQ) were administered to the patients and healthy control group. Results: The scores of the vaginismus group for secure attachment scores were statistically significantly lower than the healthy control group while there was no difference between the groups for the fearful, preoccupied and dismissive attachment subscale scores. GRISS total and subscale scores were statistically higher in women with an insecure attachment style when the total sample as divided into two groups as secure and insecure attached individuals. Conclusions: These findings taken together support the notion that insecure attachment may be an important factor in the pathogenesis of vaginismus.Öğe Brain Tumors and Atypical Psychiatric Symptoms: Two Case Presentations(Yerkure Tanitim & Yayincilik Hizmetleri A S, 2018) Akan, Mustafa; Erbay, Lale Gonenir; Erbay, Mehmet Fatih; Unal, Suheyla[Abstract Not Available]Öğe Brain tumors and atypical psychiatric symptoms: two case presentations(Yerkure tanıtım & yayıncılık hızmetlerı a s, cumhuryet cad 48-3b, harbıye, ıstanb, 34367, turkey, 2018) Akan, Mustafa; Erbay, Lale Goneni; Erbay, Mehmet Fatih; Unal, SuheylaÖğe Cerebral MR Spectroscopy Evaluation of the Neuroprotective Effects of Lithium and Olanzapine in Bipolar Affective Disorder Patients(Universitatsverlag Ulm Gmbh, 2008) Cumurcu, Birgul Elbozan; Karlidag, Rifat; Sarac, Kaya; Unal, Suheyla; Ozcan, Cemal; Erkorkmaz, UnalAim: We used the NAA measurements obtained by cerebral magnetic resonance spectroscopy to evaluate the neuroprotective effects of lithium and olanzapine in bipolar affective disorder patients in remissions. Methods:Ten bipolar affective disorder patients on lithium treatment for the last six years and who had not experienced a manic or depressive attack for the last three years and were followed up at the psychiatry outpatients department were included in the study. The patients were evaluated while on lithium, 14 days after lithium was stopped and at the end of the 411 week following olanzapine initiation, for a total of three times. Each evaluation consisted of a psychiatric interview, the Hamilton Depression Rating Scale (HDRS) and the Bech-Rafaelson Mania Scale (BRMS) in addition to MR spectroscopy imaging. Results: The cases were compared with a control group consisting of 10 age- and sex-matched healthy subjects. We measured the N-acetyl aspartate (NAA) peak quantitatively in the right dorsolateral prefrontal cortex (DLPF) and left hippocampus areas on MR spectroscopy and checked the ratio to the creatine (Cr) peak. The values from all three imaging studies were compared with each other and with the control subjects. Conclusions: There was no statistically significant difference between the NAA/Cr ratios of the patients receiving lithium, those not on medications or those receiving olanzapine and the healthy subjects. We did not observe any change in cerebral NAA levels following lithium and olanzapine treatment in bipolar affective disorder patients in remission.Öğe Does Psychodrama Affect Perceived Stress, Anxiety-Depression Scores and Saliva Cortisol in Patients with Depression?(Korean Neuropsychiatric Assoc, 2018) Erbay, Lale Gonenir; Reyhani, Ismail; Unal, Suheyla; Ozcan, Cemal; Ozgocer, Tuba; Ucar, Cihat; Yildiz, SedatObjective Little is known about the effects of psychodrama group therapy on the level of stress, anxiety and depression of the group members, and the biological markers of stress. The aim of this study test cortisol level as a biological reflection of some mental characteristics gained by the psychodrama method in coping with stress. Methods Depressive patients aged between 18 and 65 years, who diagnosed with depression according to DSM-5, without psychiatric comorbidity, who do not use drugs and were available for psychodrama were enrolled into the study. These patients were evaluated using the Perceived Stress Scale, State-Trait Anxiety Inventory and Beck Depression Inventory. In order to observe the circadian rhythm of cortisol, samples were collected from the participants before lunch, before dinner and before going to sleep on the day before psychodrama and on the 0, 15th, and 30th minutes after awakening in the morning of the psychodrama day; as well as just before and after the psychodrama session. Saliva cortisol level just before the initial session of psychodrama group therapy was compared with the saliva cortisol level just after the last psychodrama session at the end of 16 weeks. Results Statistically significant difference was determined between the scores of perceived stress scale, STAI-1, STAI-2, beck depression inventory and salivary cortisol level before and after psychodrama session. There was significant decrease in both the scale scores and salivary cortisol after vs. before psychodrama. Conclusion This results is important as it shows the biological aspect of clinical improvement. Further studies would provide us with better understanding of the effects of psychodrama group psychotherapy on depressive mood and biological projections by means of short-term and long-term follow-up studies.Öğe Does psychodrama affect perceived stress, anxiety-depression scores and saliva cortisol in patientswith depression?(Korean neuropsychıatrıc assoc, rn 522, g-fıve central plaza 1685-8 seocho 4-dong, seocho-gu, seoul, 137-882, south korea, 2018) Erbay, Lale Gonenir; Reyhani, Ismail; Unal, Suheyla; Ozcan, Cemal; Ozgocer, Tuba; Ucar, Cihat; Yildiz, SedatObjective Little is known about the effects of psychodrama group therapy on the level of stress, anxiety and depression of the group members, and the biological markers of stress. The aim of this study test cortisol level as a biological reflection of some mental characteristics gained by the psychodrama method in coping with stress. Methods Depressive patients aged between 18 and 65 years, who diagnosed with depression according to DSM-5, without psychiatric comorbidity, who do not use drugs and were available for psychodrama were enrolled into the study. These patients were evaluated using the Perceived Stress Scale, State-Trait Anxiety Inventory and Beck Depression Inventory. In order to observe the circadian rhythm of cortisol, samples were collected from the participants before lunch, before dinner and before going to sleep on the day before psychodrama and on the 0, 15th, and 30th minutes after awakening in the morning of the psychodrama day; as well as just before and after the psychodrama session. Saliva cortisol level just before the initial session of psychodrama group therapy was compared with the saliva cortisol level just after the last psychodrama session at the end of 16 weeks. Results Statistically significant difference was determined between the scores of perceived stress scale, STAI-1, STAI-2, beck depression inventory and salivary cortisol level before and after psychodrama session. There was significant decrease in both the scale scores and salivary cortisol after vs. before psychodrama. Conclusion This results is important as it shows the biological aspect of clinical improvement. Further studies would provide us with better understanding of the effects of psychodrama group psychotherapy on depressive mood and biological projections by means of short-term and long-term follow-up studies.Öğe Does Toxoplasma gondii play a role in obsessive-compulsive disorder? Response(Elsevier Ireland Ltd, 2012) Miman, Ozlem; Mutlu, Elif Aktan; Ozcan, Ozlem; Atambay, Metin; Karlidag, Rifat; Unal, Suheyla[Abstract Not Available]Öğe The effect of Ramadan fasting on mental health and some hormonal levels in healthy males(Springer, 2023) Akan, Mustafa; Unal, Suheyla; Gonenir Erbay, Lale; Taskapan, Mehmet CagatayBackgroundMillions of Muslims around the world fast during the holy month of Ramadan as a requirement of their religion Islam. Studies have reported varying effects of Ramadan fasting on mental health and various hormones. This study aimed to examine the effects of Ramadan fasting on mental health and plasma Leptin, Ghrelin, Neuropeptide Y (NPY), Growth Hormone levels in healthy individuals, and to evaluate the possible relationship between their hormone values and scale scores. Male healthcare professionals working at a university hospital without any psychiatric disease were included in the study. In the last week before Ramadan and in the first week after Ramadan, participants' blood samples were taken at 8.00 in the morning after 12 h of fasting, taking into account the release pattern and pulsatile release of these hormones in order to measure plasma Leptin, Ghrelin, NPY and Growth Hormone levels. Simultaneously, a sociodemographic data form, the Brief Symptom Inventory (BSI) and the Scale of Dimensions of Interpersonal Relationships were applied to participants.ResultsThe sample of the study included a total of 40 healthcare professionals. Participants' BSI interpersonal sensitivity and phobic anxiety subscales scores and their general severity and positive symptom distress index scores decreased significantly after Ramadan compared to those measured before Ramadan. (p < 0.001, p = 0.020, p = 0.042, p = 0.006 respectively). Also participants' ghrelin levels increased significantly after Ramadan compared to those measured before Ramadan (p < 0.001).ConclusionsThe effects of Ramadan fasting on mental health may be mediated by some psychoneuroendocrine mechanisms. In order to elucidate these mechanisms that mediate the effect of Ramadan fasting on mental health, there is a need for better-structured studies with larger samples and more variables.Öğe Effects of Relaxation Exercises and Music Therapy on the Psychological Symptoms and Depression Levels of Patients with Schizophrenia(W B Saunders Co-Elsevier Inc, 2016) Kayak, Funda; Unal, Suheyla; Yilmaz, EminePurpose: This study aims to identify the effects of relaxation exercises and music therapy on the psychological symptoms and depression levels of patients with chronic schizophrenia. Materials and methods: This semi-experimental study was conducted using pre- and post-tests with a control group. The study population consists of patients with schizophrenia who regularly attended community mental health centers in the Malatya and Elazig provinces of Turkey between May 2015 and September 2015. The study's sample consists of 70 patients with schizophrenia (n = 35 in the control group; n = 35 in the experimental group) who were selected randomly based on power analysis. The Patient Information Form, the Brief Psychiatric Rating Scale (BPRS) and the Calgary Depression Scale for Schizophrenia (CDSS) were used for data collection. Patients in the experimental group participated in relaxation exercises and music therapy 5 times a week for 4 weeks. The experimental group of 35 persons was divided into three groups of approximately 10-12 individuals in order to enable all participants to attend the program. No intervention was applied to the patients in the control group. The data were evaluated using percentage distribution, arithmetic means, standard deviations, Chi-square and independent samples t-tests. Results: The study found that patients in the experimental group showed a decrease in total mean scores on the BPRS and CDSS; the difference between the post-test scores of the experimental group and the post-test scores of the control group was statistically significant (p < 0.05). The practice of relaxation exercises and music therapy was proven to be effective in reducing schizophrenic patients' psychological symptoms and levels of depression. Conclusion: Relaxation exercises and music therapy can be used as a complementary therapy in the medical treatment of patients with chronic schizophrenia. (C) 2016 Elsevier Inc. All rights reserved.Öğe Elements Levels and Glucose-6-Phosphate Dehydrogenase Activity in Blood of Patients with Schizophrenia(Kare Publ, 2012) Kaya, Burhanettin; Akdag, Nihal; Fadillioglu, Ersin; Taycan, Serap Erdogan; Emre, Mehmet H.; Unal, Suheyla; Sayal, AhmetObjectives: Glucose-6-phosphate dehydrogenase (G6PD) is the rate limiting enzyme of the hexose monophosphate cascade which plays role in the synthesis of nucleotide, reduced glutathion, fatty acid and cholesterol precursors. At the same time, it is an important enzyme for neuronal development during and after fetal life and for neurotransmitters. Serum elements are necessary for neuronal development and synthesis and activity of enzymes and hormones. The aim of this study was to compare serum levels of some elements and G6PD enzyme activity in schizophrenic patients with those in healthy individuals. Methods: This study involved blood serum analysis of 32 schizophrenia patients and 32 age-and sex-matched healthy controls. Copper, zinc, iron, magnesium levels were determined with a double lighted, deuterium sourced, background proof reading fire atomic spectrophotometer and in order to determine aluminum and manganese levels, a graphite tube atomizer spectroscope was used. G6PD enzyme activity was analyzed by the Glock and Mclean Method. Results: This analysis revealed higher levels of G6PD activity, copper, iron, magnesium and aluminum in schizophrenia patients compared to controls, whereas zinc and manganese levels showed a decreasing trend on the contrary. Discussion: The higher levels of G6PD activity in schizophrenic patients is not consistent with the literature in general. It is considered that results on G6PD and element levels may be explained as the effects of specific hormones, antipsychotic medications, or by schizophrenia itself. Conclusion: The elements we investigated and G6PD are important for the antioxidant system. Thus changing levels of elements in patients with schizophrenia may lead to disturbed functions of antioxidant enzymes and G6PD. Further researches on this subject conducted with larger and drug naive patient groups are needed.Öğe Epigenetic mechanisms in the development of psychiatric disorders(Kure Iletisim Grubu A S, 2010) Erol, Deniz; Elyas, Zeynep; Unal, SuheylaEpigenetics is defined as the study of heritable changes of gene function that occur without a change in the nucleotide sequence of DNA. Aberrant epigenetic mechanisms have been directly implicated in certain human diseases. There is much evidence that epigenetic regulation is involved in neurogenesis, neuronal plasticity, learning and memory, and in psychiatric disorders such as depression, addiction, schizophrenia, and cognitive dysfunction. In this review, the epigenetics mechanisms and their role in the development of psychiatric disorders were discussed.Öğe Evaluation of Transcranial Magnetic Stimulation Efficiency in Major Depressive Disorder Patients: A Magnetic Resonance Spectroscopy Study(Korean Neuropsychiatric Assoc, 2019) Erbay, Mehmet Fatih; Zayman, Esra Porgali; Erbay, Lale Gonenir; Unal, SuheylaObjective Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for major depressive disorder (MDD). This study evaluated the antidepressant effect of rTMS and examined how it affected N-asetyl aspartate (NAA), choline (Cho), creatine (Cr), lactate (Lac), inyoinositol (mins), glutamate (Glu), glutathione (GSH), and glutamine (Gln) metabolite levels in the left dorsolateral prefrontal cortex (DLPFC) of MDD patients who were not receiving antidepressant medication. Methods In total, 18 patients (10 female, 8 male) were evaluated. Each patient underwent H magnetic resonance spectroscopy (H-MRS) before and within 3 days of completion of TMS therapy. All patients completed 20 sessions of rTMS directed at the left DLPFC over a 2-week period. The Hamilton Depression Scale (HAMD) scores of patients were calculated, and their responses to treatment were assessed within 1-3 days of completion of TMS. Results We found statistically significant differences in HAMD scores before and after rTMS. Moreover, the peak metabolite ratios of NAA/Cr, GSH/Cr, and Gln/Cr were significantly higher after rTMS compared to those before rTMS. Conclusion Increased understanding of the mechanism of action of TMS will improve its application and may stimulate development of new generation therapeutic agents.Öğe Forensic aspect of the frontal lobe syndrome: a case report(Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2011) Kartalci, Sukru; Unal, Suheyla; Ozdemir, SerdalIn this case report, it is discussed a patient with frontal lobe syndrome (FLS) who was subjected to forensic and psychiatric observation. A 39 year-old woman have presented severe disabilities in daily life activities after traumatic brain injury. She showed slowness, reduction of emotion and apathy at her clinical evaluation. Despite the notably impairment in social behavior, she was unaware of this situation. Computerized tomography of head was conducted atrophy of frontal lobe. It was diagnosed as a FLS. FLS consists of two distinct clinical syndromes. The orbitofrontal syndrome is the most well known and consists of major antisocial behavior. Apathetic states lie at the other end of the syndrome. Psychiatry generally focuses to orbitofrontal syndrome in criminal behaviour. However in this case, it is discussed a patient with apathetic FLS in terms of forensic psychiatry. (Anatolian Journal of Psychiatry 2011;12:160-162)Öğe Help Seeking Behavior and Related Factors in Schizophrenia Patients: A Comparative Study of Two Populations from Eastern and Western Turkey(Yerkure Tanitim & Yayincilik Hizmetleri A S, 2015) Yalvac, H. Dilek; Kotan, Zeynep; Unal, SuheylaHelp seeking behavior and related factors in schizophrenia patients: a comparative study of two populations from eastern and western Turkey Objective: In this study, it is aimed to investigate and compare the properties of help-seeking behaviour of schizophrenia patients from two districts situated in eastern and western Turkey. Method: Thirty one schizophrenia patients admitted to Tatvan State Hospital in 2006 and 41 schizophrenia patients admitted to Menemen State Hospital in 2007 were recruited in the study. All the patients were in remission. A semi-structured, short questionnaire type interview was carried out with the patients inquiring about their socio-demographic properties and the ways they explain and seek help for their illness. Results: The populations from Tatvan and Menemen significantly differed in terms of educational and income levels. Mean education duration of patients was 4.3 +/- 4.2 years for Tatvan and 6.8 +/- 3.5 years for Menemen (p=0.008). Fourty five percent of patients from Tatvan were of low income level and 54% of patients from Menemen were of middle-income level (p=0.016). Seventy four percent of all patients seeked help from religious sources for their illness. The percentage of patients seeking for psychiatric help was 85 for Menemen and 32 for Tatvan (p<0.001). Patients with education level of secondary-school and higher seeked for psychiatric help more than the less educated patients (p=0.039). Seventy one percent of all patients were advised to consult a psychiatrist by their family members. Discussion: This study revealed that a substantial proportion of schizophrenia patients from the two different districts were in seek of help from religious sources. Seeking for psychiatric help increased with increasing education level which indicates the importance of implementation and development of psychoeducational programs for both patients and their families.Öğe Investigation of the relationship between adult attention deficit hyperactivity disorder and reinforcement sensiti(Klinik Psikiyatri Dergisi, 2024) Zayman, Esra Porgali; Unal, Suheyla; Cumurcu, Hatice Birgul; Ozcan, Ozlem Ozel; Bilici, Rabia; Zayman, ErsahObjective: It is known that adult ADHD coexistence is high in patients with substance use disorder (SUD). With the prediction that the Behavioral Activation System (BAS) and Behavioral Inhibition System (BIS), which Gray suggested to underlie motivated behavior, may be effective in these two psychopathological conditions, this study investigated the relationship between BIS/DAS dimensions and ADHD symptoms in substance abusers. Method: The study included 91 male patients over the age of 18 diagnosed with substance use disorder according to DSM-5 who were admitted to the AMATEM outpatient clinic of Elazig Mental Health and Diseases Hospital for outpatient treatment and 99 male healthy controls with similar sociodemographic characteristics. Participants were given a form in which sociodemographic and substance use questions were asked and Adult Attention Deficit Hyperactivity Disorder SelfScale (BIS/BAS). Results: In our study, the prevalence of adult ADHD among substance abusers was found to be 10.1%. When the groups were compared according to the scale scores, a statistically significant difference was found between the individuals with substance use disorder and the control group according to BIS-anxiety, FFFSfear, WURS scale scores and total ASRS scores. Conclusion: Our findings suggest that in substance abusers, an attention by increasing the sense of pleasure rather than hyperactivity that impulsivity may provide.Öğe An investigation on the effects of music training on attention and working memory in adults(Cumhurıyet unıv tıp fak psıkıyatrı anabılım dalı, cumhurıyet unıv tıp fak psıkıyatrı abd, sıvas, 58140, turkey, 2017) Yesil, Bahar; Unal, SuheylaObjective: Determining the effects of music training on attention and working memory in adult music trainees using neuropsychological tests. Methods: The study was conducted within January-June 2014 at the Music Department of Inonu University. Twenty-two students of age 18-26 were matched one to one in terms of age, gender, level of academic education and dominant hand. Participants with substance abuse, psychiatric and neurological disease were excluded from study. ASRS, Stroop and WMS-R were applied on first and fourth year students. Results: The sample consisted of 24 women and 20 men. The mean age was 22 +/- 1.5 years and the mean academic level of education was 15 +/- 1.5 years. There was no significant difference between first and fourth year students in terms of ASRS-A, ASRS-B and ASRS total scores. There was no significant difference between groups in pre-university music experience. Fourth year students were better at greyscale word reading, color word reading and box color statement in Stroop. There was no significant difference in word color statement. Fourth year students were better in reverse month counting and counting by sevens in WMS-R. No significant difference was found in countdown range, short and long-term verbal and visual recognition, memory, mental control and concentration. Conclusion: Long-term and regular music training did not affect attention shifting in adults significantly, but caused improvement in some tests requiring working memory activity. Irregular music experience did not have significant contribution. Regular and intensive music practice may have functional effects on cognition in adults. (Anatolian Journal of Psychiatry 2017; 18(6): 531-535)