Multiple PRP injections are more effective than single injections and hyaluronic acid in knees with early osteoarthritis a randomized double blind placebo controlled trial

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Tarih

2015

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Knee Surgery, Sports Traumatology, Arthroscopy

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Purpose To compare the effectiveness of intraarticular (IA) multiple and single platelet-rich plasma (PRP) injections as well as hyaluronic acid (HA) injections in different stages of osteoarthritis (OA) of the knee. Methods A total of 162 patients with different stages of knee OA were randomly divided into four groups receiving 3 IA doses of PRP, one dose of PRP, one dose of HA or a saline injection (control). Then, each group was subdivided into two groups: early OA (Kellgren–Lawrence grade 0 with cartilage degeneration or grade I–III) and advanced OA (Kellgren–Lawrence grade IV). The patients were evaluated before the injection and at the 6-month followups using the EuroQol visual analogue scale (EQ-VAS) and International Knee Documentation Committee (IKDC) subjective scores. Adverse events and patient satisfaction were recorded.

Açıklama

Knee Surgery, Sports Traumatology, Arthroscopy, 0–0.

Anahtar Kelimeler

Hyaluronic acid, Intraarticular injection, Knee osteoarthritis, Platelet-rich plasma

Kaynak

Knee Surgery, Sports Traumatology, Arthroscopy

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0

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0

Künye

Gökhan, G., Görmeli, C. A., Ataoğlu, M. B., Çolak, C., & Aslantürk, O. (2015). Multiple Prp İnjections Are More Effective Than Single İnjections And Hyaluronic Acid İn Knees With Early Osteoarthritis A Randomized Double Blind Placebo Controlled Trial. Knee Surgery, Sports Traumatology, Arthroscopy, 0–0.