Longitudinal changes in parafoveal microvascular structure in diabetic macular edema

Basit Öğe Kaydı
dc.contributor.authorPolat, Nihat
dc.contributor.authorYologlu, Saim
dc.date.accessioned2024-08-04T19:42:43Z
dc.date.available2024-08-04T19:42:43Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: This study aims to investigate retinal microvascular changes according to increases and decreases in macular edema, explain how these changes are associated with differentcapillary plexuses in diabetic macular edema (DME), and provide evidence for treatment efforts. Materials and Methods: 21 eyes of diabetic patients with DME who were treated with intravitreal injections were investigated. The control group was assigned age-and sexmatched healthy subjects. The patients were divided into decreased edema and increased edema subgroups to compare microvascular changes before and after treatment. Optical Coherence Tomography Angiography (OCTA) parameters were used for comparison. Results: There were significant differences in visual acuity and mean OCTA parameters between the main patient group and the control group (all P<0.05). There were no significant differences between the two DME subgroups in terms of baseline values (all P>0.05).The foveal avascular zone (FAZ) in the deep capillary plexus (DCP) was significantly lowerin the decreased edema group; however, there were no significant differences in the otherparameters between the two subgroups after 6 months of treatment. The changes in the FAZ in the DCP ranged from 2126.82 ± 1858.59 µm2 to 711.64 ± 738.55 µm2 in the decreased edema group (P = 0.013) and from 2231.50 ± 2187.66 µm2to 2025.50 ± 2020 µm2in the increased edema group (P = 0.575) after 6 months of treatment. Conclusion: Deep retinal ischemia can actually recover after proper treatment. However, we were unable to find a significant change in the density of the parafoveal vessel in DME after treatment; the changes in the FAZ of the DCP were the most prominent indicator of that improvement.en_US
dc.identifier.doi10.5455/annalsmedres.2023.05.123
dc.identifier.endpage1187en_US
dc.identifier.issn2636-7688
dc.identifier.issue10en_US
dc.identifier.startpage1181en_US
dc.identifier.trdizinid1204110en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2023.05.123
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1204110
dc.identifier.urihttps://hdl.handle.net/11616/88620
dc.identifier.volume30en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleLongitudinal changes in parafoveal microvascular structure in diabetic macular edemaen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu