Fibrin sealant use in pilonidal sinus systematic review

Yükleniyor...
Küçük Resim

Tarih

2016

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

World journal of gastrointestinal srgery

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

To review the current data about the success rates of fibrin sealant use in pilonidal disease. METHODS: Fibrin sealant can be used for different purposes in pilonidal sinus treatment, such as filling in the sinus tracts, covering the open wound after excision and lay-open treatment, or obliterating the subcutaneous dead space before skin closure. We searched Pubmed, Google-Scholar, Ebsco-Host, clinicaltrials, and Cochrane databases and found nine studies eligible for analysis; these studies included a total of 217 patients (84% male, mean age 24.2 ± 7.8). RESULTS: In cases where fibrin sealant was used to obliterate the subcutaneous dead space, there was no reduction in wound complication rates (9.8% vs 14.6%, P = 0.48). In cases where sealant was used to cover the laid-open area, the wound healing time and patient comfort were reported better than in previous studies (mean 17 d, 88% satisfaction). When fibrin sealant was used to fill the sinus tracts, the recurrence rate was around 20%, despite the highly selected grouping of patients. CONCLUSION: Consequently, using fibrin sealant to decrease the risk of seroma formation was determined to be an ineffective course of action. It was not advisable to fill the sinus tracts with fibrin sealant because it was not superior to other cost-effective and minimally invasive treatments. New comparative studies can be conducted to confirm the results of sealant use in covering the laid-open area.

Açıklama

Anahtar Kelimeler

Pilonidal disease, Fibrin sealant, Evidence base medicine, Systematic review

Kaynak

World journal of gastrointestinal srgery

WoS Q Değeri

Scopus Q Değeri

Cilt

8

Sayı

3

Künye

Kayaalp, C. Ertuğrul, İ. Tolan, K. Sümer, F. (2016). Fibrin sealant use in pilonidal sinus systematic review. World journal of gastrointestinal srgery. 8(3): 266-273.