Fibrin sealant use in pilonidal sinus systematic review

dc.authorid109262en_US
dc.contributor.authorKayaalp, Cüneyt
dc.contributor.authorErtuğrul, İsmail
dc.contributor.authorTolan, Kerem
dc.contributor.authorSümer, Fatih
dc.date.accessioned2017-09-12T07:21:15Z
dc.date.available2017-09-12T07:21:15Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractTo review the current data about the success rates of fibrin sealant use in pilonidal disease. METHODS: Fibrin sealant can be used for different purposes in pilonidal sinus treatment, such as filling in the sinus tracts, covering the open wound after excision and lay-open treatment, or obliterating the subcutaneous dead space before skin closure. We searched Pubmed, Google-Scholar, Ebsco-Host, clinicaltrials, and Cochrane databases and found nine studies eligible for analysis; these studies included a total of 217 patients (84% male, mean age 24.2 ± 7.8). RESULTS: In cases where fibrin sealant was used to obliterate the subcutaneous dead space, there was no reduction in wound complication rates (9.8% vs 14.6%, P = 0.48). In cases where sealant was used to cover the laid-open area, the wound healing time and patient comfort were reported better than in previous studies (mean 17 d, 88% satisfaction). When fibrin sealant was used to fill the sinus tracts, the recurrence rate was around 20%, despite the highly selected grouping of patients. CONCLUSION: Consequently, using fibrin sealant to decrease the risk of seroma formation was determined to be an ineffective course of action. It was not advisable to fill the sinus tracts with fibrin sealant because it was not superior to other cost-effective and minimally invasive treatments. New comparative studies can be conducted to confirm the results of sealant use in covering the laid-open area.en_US
dc.identifier.citationKayaalp, C. Ertuğrul, İ. Tolan, K. Sümer, F. (2016). Fibrin sealant use in pilonidal sinus systematic review. World journal of gastrointestinal srgery. 8(3): 266-273.en_US
dc.identifier.doi10.4240/wjgs.v8.i3.266en_US
dc.identifier.endpage273en_US
dc.identifier.issue3en_US
dc.identifier.startpage266en_US
dc.identifier.urihttps://hdl.handle.net/11616/7748
dc.identifier.volume8en_US
dc.language.isoenen_US
dc.publisherWorld journal of gastrointestinal srgeryen_US
dc.relation.ispartofWorld journal of gastrointestinal srgeryen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPilonidal diseaseen_US
dc.subjectFibrin sealanten_US
dc.subjectEvidence base medicineen_US
dc.subjectSystematic reviewen_US
dc.titleFibrin sealant use in pilonidal sinus systematic reviewen_US
dc.typeArticleen_US

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