Synthesis and antimicrobial activities of some bridged bis-benzimidazole derivatives

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Küçük Resim

Tarih

2011

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Turkish Journal of Chemistry

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Öz (İngilizce): Some bis-benzimidazoles derivatives bearing allyl, crotyl, cinammyl, furfuryl, and thenyl groups were synthesized and their in vitro antimicrobial activity determined against gram-positive and gram-negative bacteria, and fungi by disk-diffusion method. The structures of all new compounds were identified by 1 H-NMR, 13C-NMR, and FT-IR spectroscopic techniques and elemental analysis. All the compounds synthesized in this work were examined for their in vitro antimicrobial activities against gram-positive (Staphylococcus aureus and Bacillus megaterium) and gram-negative bacteria (Klebsiella pneumoniae and Escherichia coli ), and the yeasts like fungi (Candida globrata and Candida tropicalis). Compared to the reference substances, Cefozine and nystatin, most of the compounds showed high antibacterial and antifungal activities against studied strains with inhibition zones between 8 and 28 mm.

Açıklama

Anahtar Kelimeler

Mühendislik, Kimya

Kaynak

Turkish Journal of Chemistry

WoS Q Değeri

Q3

Scopus Q Değeri

Cilt

35

Sayı

4

Künye

HASAN K., ÜLKÜ Y., NİHAT Ş., Ayşe Nilay Ö. (2011). Synthesis and antimicrobial activities of some bridged bis-benzimidazole derivatives, Turkish Journal of Chemistry, İnönü Üniversitesi, Malatya.