Is edema in minimal change disease of childhood really hypovolemic

dc.authorid31161en_US
dc.authorid216929en_US
dc.authorid113274en_US
dc.authorid102525en_US
dc.contributor.authorTabel, Yılmaz
dc.contributor.authorMungan, İlke
dc.contributor.authorKarakurt, Cemşit
dc.contributor.authorKoçak, Gülemdar
dc.contributor.authorGüngör, Serdal
dc.date.accessioned2018-01-25T12:48:50Z
dc.date.available2018-01-25T12:48:50Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.descriptionInt Urol Nephrol (2008) 40:757–761.en_US
dc.description.abstractObjectives In this study, we aimed to find out whether children with minimal change disease can be classified as hypervolemic by objective measures. Methods Eighteen children with minimal change disease diagnosed at our department between November 2005 and May 2007 were included in this study. All patients were newly diagnosed or relapsed but were steroid free for at least 6 months. In the first week of edema and when edema resolved (5–7 days after initiation of therapy), weight, height and blood pressure were obtained from all patients. Serum and plasma samples were taken following a starvation period of 12–14 h. The volume load of all patients was evaluated, measuring the inferior vena cava indices in each stage by echocardiography. Results Average weight at presentation was 8.5% higher than the ideal (dry) weight. There were significant differences between the first and posttreatment body weights, abdomen circumference, and systolic and diastolic blood pressure values (P\0.05 for each). The inferior vena cava index (IVCI) values decreased significantly after diuretic treatment (P\0.001), while inferior vena cava collapsibility index (IVCCI) values increased in the post-treatment period (P\0.001). Conclusion We believe that a close follow-up of hypervolemic children with MCD, treated solely with easy-to-handle diuretics instead of I.V. albumin and diuretics may properly solve the edematous state in these patients.en_US
dc.identifier.citationTabel, Y., İlke, Mungan, Karakurt, C., Koçak, G., & Güngör, S. (2008). Is Edema İn Minimal Change Disease Of Childhood Really Hypovolemic . Int Urol Nephrol, 0–0.en_US
dc.identifier.endpage0en_US
dc.identifier.issue0en_US
dc.identifier.startpage0en_US
dc.identifier.urihttps://link.springer.com/content/pdf/10.1007%2Fs11255-008-9344-9.pdf
dc.identifier.urihttps://hdl.handle.net/11616/8019
dc.identifier.volume0en_US
dc.language.isoenen_US
dc.publisherInt Urol Nephrol, 0–0.en_US
dc.relation.ispartofInt Urol Nephrol, 0–0.en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChildhooden_US
dc.subjectDiureticen_US
dc.subjectEdemaen_US
dc.subjectMinimal change diseaseen_US
dc.subjectNephrotic syndromeen_US
dc.titleIs edema in minimal change disease of childhood really hypovolemicen_US
dc.typeArticleen_US

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