Relationship between mean platelet volume and vitamin D deficiency in fibromyalgia

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dc.authoridErsoy, Yuksel/0000-0002-8035-4532
dc.authorwosidSolmaz, Dilek/B-1448-2016
dc.authorwosidYildirim, Tulay/AAB-5030-2021
dc.authorwosidErsoy, Yuksel/S-7503-2016
dc.contributor.authorYildirim, Tulay
dc.contributor.authorSolmaz, Dilek
dc.contributor.authorAkgol, Gurkan
dc.contributor.authorErsoy, Yuksel
dc.date.accessioned2024-08-04T20:42:44Z
dc.date.available2024-08-04T20:42:44Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To investigate whether vitamin D deficiency is associated with high mean platelet volume (MPV) in fibromyalgia (FMS) compared to healthy controls. Methods: Ninety-nine patients with fibromyalgia and ninety-nine age-and sex-matched healthy female control subjects were included. Tenderness was evaluated by applying pressure (4 kg/cm(2)) over 18 specific body points, and the number of tender points was recorded. FMS patients completed visual analog scales (VAS) to evaluate their level of pain and were evaluated with the FMS Impact Questionnaire (FIQ) and Beck Depression Inventory (BDI). In all cases, platelet count and MPV were measure as part of each full blood count. Serum 25(OH) D3 levels were analyzed with Enzyme-Linked ImmunoSorbent Assay (ELISA). Patients were divided into three groups as follows: Group 1, vitamin D level of <10 ng/ml (n=33); Group 2, vitamin D level of 10-20 ng/ml (n=3); and Group 3, vitamin D level of > 20 ng/ml (n=33). Results: MPV values were significantly higher in the vitamin group 1 compared to the control group. There was no significant difference between the vitamin group 3 and the controls. A negative correlation was determined between MPV and vitamin D status or 25 (OH) D level. Conclusion: Vitamin D deficiency may contribute to an increase in MPV levels, which is a risk factor in cardiovascular disease (CVD) in FMS.en_US
dc.identifier.endpage1270en_US
dc.identifier.issn0970-938X
dc.identifier.issn0976-1683
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84993969575en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1265en_US
dc.identifier.urihttps://hdl.handle.net/11616/97557
dc.identifier.volume27en_US
dc.identifier.wosWOS:000393482000052en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherScientific Publishers Indiaen_US
dc.relation.ispartofBiomedical Research-Indiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFibromyalgiaen_US
dc.subjectMean platelet volumeen_US
dc.subjectVitamin Den_US
dc.titleRelationship between mean platelet volume and vitamin D deficiency in fibromyalgiaen_US
dc.typeArticleen_US

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