Farklı Hassasiyet Giderici Ajanların Demineralizasyona Karşı Stabilitesinin Mikro Bilgisayarlı Tomografi Kullanılarak Değerlendirilmesi
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Dosyalar
Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
İnönü Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu deneysel çalışmanın amacı; farklı remineralize edici mekanizmalara
sahip olan hassasiyet giderici ajanların dentin tübüllerini tıkamadaki etkinliklerini, asit
maruziyeti karşısındaki stabilitelerini kıyaslamalı olarak değerlendirmek için, mikro-BT
kullanarak incelemektir.
Materyal ve metot: Bu çalışmada 40 adet çürüksüz insan daimi molar dişleri
kullanıldı. Hassas kesme cihazı ile kole bölgesinden 40 adet dentin bloğu elde edildi.
Diskler Enamelast, Nupro Sensodyne Paste, Tooth Mousse, Colgate Sensitive Pro Relief Desensitizing Paste olmak üzere rasgele 4 gruba ayrıldı. Her bir grup sırasıyla
hiçbir işlem yapılmadan, hassasiyet giderici ajan uygulandıktan sonra ve demineralize
edici ajanda bekletildikten sonra olmak üzere 3 defa mikro-BT’de tarandı. Ayrıca her
gruptan bir örnek SEM ile görüntülendi.
Bulgular: İstatistiksel analiz hassasiyet giderici ajan uygulandıktan sonra Nupro
ile Colgate grupları arasında mineral yoğunluk değişimi olduğunu gösterdi (p=0.042).
Diğer gruplar arasında mineral yoğunluk düzeyleri açısından istatistiksel olarak anlamlı
bir farklılık bulunmadı. Mineral yoğunluğu en fazla artan grup Colgate olmuş, bunu
sırasıyla Enamelast, Toothmouse ve son olarak Nupro grupları izlemiştir.
Demineralizasyon sonrası mineral yoğunluk değişimlerinde Toothmouse ile Colgate
grupları arasında (p=0.002) ve Enamelast ile Colgate grupları arasında (p<0.001)
anlamlı bir fark saptandı. Diğer gruplar arasında ise anlamlı bir farklılık bulunmadı.
Mineral yoğunluk değişim en fazla Enamelast grubunda olmuş bunu sırasıyla Tooth
Mousse, Nupro ve Colgate grupları izlemiştir.
Sonuçlar: Çalışmada kullanılan tüm örneklerde hassasiyet giderici ajanlar
uygulandıktan sonra mineral yoğunluk değerleri artış göstermesine rağmen
demineralizasyona karşı yeterli direnci gösterememiştir. Mineral yoğunluğundaki en
fazla artış ve demineralizasyona karşı en fazla direnç Colgate grubunda olmuştur.
Anahtar kelimeler: Demineralizasyon, dentin, florid, hassasiyet giderici ajan,
mikro-BT
Aim: The aim of this experimental study is to examine the effectiveness of desensitizing agents with different remineralizing mechanisms in occluding dentinal tubules and their stability against acid exposure using micro-CT device. Material and method: In this study, 40 permanent human molar teeth were used. Forty dentin blocks were obtained from the dentinoenamel junction with the precision cutting device. The discs were randomly divided into 4 groups as Enamelast, Nupro Sensodyne Paste, Tooth Mousse, and Colgate Sensitive Pro-Relief Desensitizing Paste. Each group was scanned 3 times on micro-CT, without any action, after the application of desensitizing agent, and after holding the demineralizing agent, respectively. In addition, a sample from each group was imaged with SEM. Result: Statistical analysis showed a change in mineral density between the Nupro and Colgate groups after application of the desensitizing agent (p=0.042). There was no significant difference between the other groups in terms of mineral density levels. The group with the highest increase in mineral density was Colgate, followed by Enamelast, Toothmouse and Nupro groups, respectively. A significant difference was found between Toothmouse and Colgate groups (p=0.002) and between Enamelast and Colgate groups (p<0.001) in mineral density changes after demineralization. There was no significant difference between the other groups. The group with the highest decrease in mineral density value was Enamelast, followed by Tooth Mousse, Nupro and Colgate groups, respectively. Conclusion: Although mineral density values increased after the application of desensitizing agents in all samples used in the study, they did not show sufficient resistance to demineralization. The greatest increase in mineral density and the greatest resistance to demineralization were in the Colgate group. Keywords: Demineralization, dentin, fluoride, desensitizing agent, micro-CT
Aim: The aim of this experimental study is to examine the effectiveness of desensitizing agents with different remineralizing mechanisms in occluding dentinal tubules and their stability against acid exposure using micro-CT device. Material and method: In this study, 40 permanent human molar teeth were used. Forty dentin blocks were obtained from the dentinoenamel junction with the precision cutting device. The discs were randomly divided into 4 groups as Enamelast, Nupro Sensodyne Paste, Tooth Mousse, and Colgate Sensitive Pro-Relief Desensitizing Paste. Each group was scanned 3 times on micro-CT, without any action, after the application of desensitizing agent, and after holding the demineralizing agent, respectively. In addition, a sample from each group was imaged with SEM. Result: Statistical analysis showed a change in mineral density between the Nupro and Colgate groups after application of the desensitizing agent (p=0.042). There was no significant difference between the other groups in terms of mineral density levels. The group with the highest increase in mineral density was Colgate, followed by Enamelast, Toothmouse and Nupro groups, respectively. A significant difference was found between Toothmouse and Colgate groups (p=0.002) and between Enamelast and Colgate groups (p<0.001) in mineral density changes after demineralization. There was no significant difference between the other groups. The group with the highest decrease in mineral density value was Enamelast, followed by Tooth Mousse, Nupro and Colgate groups, respectively. Conclusion: Although mineral density values increased after the application of desensitizing agents in all samples used in the study, they did not show sufficient resistance to demineralization. The greatest increase in mineral density and the greatest resistance to demineralization were in the Colgate group. Keywords: Demineralization, dentin, fluoride, desensitizing agent, micro-CT
Açıklama
Anahtar Kelimeler
Demineralizasyon, dentin, florid, hassasiyet giderici ajan, mikro-BT, Demineralization
Kaynak
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Şimşek, E. (2022). Farklı Hassasiyet Giderici Ajanların Demineralizasyona Karşı Stabilitesinin
Mikro Bilgisayarlı Tomografi Kullanılarak Değerlendirilmesi. Doktora Tezi, İnönü Üniversitesi.