Life saving effect of early use of convalescent plasma inCovid-19 treatment

Basit Öğe Kaydı
dc.contributor.authorSarıcı, Ahmet
dc.contributor.authorErkurt, Mehmet Ali
dc.contributor.authorKuku, İrfan
dc.contributor.authorBiçim, Soykan
dc.contributor.authorBerber, İlhami
dc.contributor.authorKaya, Emin
dc.contributor.authorOzgul, Mustafa
dc.date.accessioned2024-08-04T19:42:39Z
dc.date.available2024-08-04T19:42:39Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAcute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus, which is detected by the transmission from bat to person in Wuhan Province of China, has shown its effect all over the world in a very short time. There is no treatment method proven effective in Coronavirus disease 2019 (COVID-19) pandemics. The whole world is still working on it. Convalescent Plasma (CP) treatment is a passive antibody treatment that has been shown to be effective during periods of epidemic disease in history. CP treatment is interesting in the treatment of virus infection without vaccine or specific treatment, such as SARSCoV-2, which causes COVID-19. The mechanisms of action of CP include neutralizing the virus by direct binding, initiating virus elimination by complement activation, antibody-dependent cellular cytotoxicity and / or phagocytosis. Neutralizing antibodies are the most important mechanisms of action. The most important point in recovery is the inactivation of the virus and the prevention of viral replication. It was demonstrated for the first time that CP significantly reduced mortality in COVID-19 disease. Our results of CP treatment in COVID-19 patients have been published. We have shown that CP is effective and safe in COVID-19 disease. We aimed to gather CP experiences up to date in COVID-19.en_US
dc.identifier.doi10.5455/annalsmedres.2021.03.228
dc.identifier.endpage2247en_US
dc.identifier.issn2636-7688
dc.identifier.issue12en_US
dc.identifier.startpage2242en_US
dc.identifier.trdizinid514743en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2021.03.228
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/514743
dc.identifier.urihttps://hdl.handle.net/11616/88554
dc.identifier.volume28en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleLife saving effect of early use of convalescent plasma inCovid-19 treatmenten_US
dc.typeReview Articleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu