The predictive value of triglyceride to high density lipoprotein cholesterol ratio in patients with isolated coronary artery ectasia
Yükleniyor...
Dosyalar
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: The pathophysiology of coronary artery ectasia (CAE) has not been clear. Dyslipidemia is a serious cause for increasing the
risk of coronary artery disease. The relationship between isolated CAE and dyslipidemia is unknown. We evaluated the triglyceride to
high-density lipoprotein cholesterol ratio (Tg to HDLc) and dyslipidemia in patients with isolated CAE.
Material and Methods: We included 60 patients and 70 controls with normal coronary arteries with similar baseline risk factors. Total
cholesterol (Tc), high-density lipoprotein cholesterol (HDLc), low-density lipoprotein cholesterol (LDLc), triglycerides (Tg) levels were
measured and Tg to HDLc ratio was calculated. Factors predicting CAE were analyzed.
Results: When compared with the controls serum Tg level and Tg to HDLc ratio were significantly higher, HDLc level was significantly
lower in the patients (p=0.001; p=0.004; p=0.001, an respectively). The multivariate logistic regression analysis revealed that Tg to
HDLc ratio (OR:1.476, 95% CI 0.1199-1.817, p=0.001) was independent factor predicting isolated CAE. In the ROC curve analysis,
Tg to HDLC ratio was found to be statistically significant with a cut-off point value of 4.2 was determined to predict isolated CAE
[AUC=0.829, (95% CI, 0.752-0.906), p=0.001].
Conclusion: Tg to HDLc ratio, HDLc and triglycerides were found to be independent factors predicting isolated CAE. These lipid
parameters and Tg to HDLc ratio may be a valuable, easily accessible, non-invasive way of predicting the presence of isolated CAE.
Açıklama
Anahtar Kelimeler
Kaynak
Annals of Medical Research
WoS Q DeÄŸeri
Scopus Q DeÄŸeri
Cilt
Sayı
Künye
Gurdal, A., Keskin, K., Sigirci, S., Cetin, S., & Orta Kilickesmez, K. (2021). The predictive value of triglyceride to high density lipoprotein cholesterol ratio in patients with isolated coronary artery ectasia . Annals of Medical Research
