Evaluation of the effects of ozone therapy on Escherichia coli-induced cytitis in rat

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dc.authoridYücel, Aytaç/0000-0003-0270-8339
dc.authoriderdogan, selim/0000-0002-9169-9771
dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authoridVardı, Nigar/0000-0003-0576-1696
dc.authoridAglamis, Erdogan/0000-0002-7497-7573
dc.authorwosidaltintas, ramazan/AAP-2348-2020
dc.authorwosidYücel, Aytaç/ABI-6137-2020
dc.authorwosiderdogan, selim/AAT-2487-2020
dc.authorwosidYAKUPOGULLARI, YUSUF/F-3966-2011
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.authorwosidKARAMAN, Abdurrahman/G-7825-2016
dc.authorwosidVardı, Nigar/C-9549-2018
dc.contributor.authorTasdemir, C.
dc.contributor.authorTasdemir, S.
dc.contributor.authorVardi, N.
dc.contributor.authorAtes, B.
dc.contributor.authorOnal, Y.
dc.contributor.authorErdogan, S.
dc.contributor.authorYucel, A.
dc.date.accessioned2024-08-04T20:43:57Z
dc.date.available2024-08-04T20:43:57Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of the study was to investigate the effect of ozone on oxidative/nitrosative stress and bladder injury caused by Escherichia coli in rat bladder. Twenty-one Wistar-Albino-type female rats included in the study were divided into three groups of equal number: (1) sham operation (control), (2) E. coli-only (EC), (3) EC + ozone. After ozone therapy for 3 days, urine and tissue samples were obtained for biochemical, microbiological, and histopathological analysis. Tissue malondialdehyde (MDA), myeloperoxidase (MPO), and nitric oxide (NO) level were increased, whereas superoxide dismutase (SOD) and glutathione peroxidase (GPx) activity was decreased in the EC group. MDA, MPO, and NO levels were decreased, whereas SOD, GPx activity was increased in the ozone-treated group. Also, there was no bacterial translocation in this group. The results of the present study suggest that ozone may be used as an agent to protect the bladder from oxidative/nitrosative stress occurring in cystitis.en_US
dc.identifier.doi10.1007/s11845-013-0926-x
dc.identifier.endpage563en_US
dc.identifier.issn0021-1265
dc.identifier.issn1863-4362
dc.identifier.issue4en_US
dc.identifier.pmid23456133en_US
dc.identifier.scopus2-s2.0-85027918011en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage557en_US
dc.identifier.urihttps://doi.org/10.1007/s11845-013-0926-x
dc.identifier.urihttps://hdl.handle.net/11616/97935
dc.identifier.volume182en_US
dc.identifier.wosWOS:000325827100005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer London Ltden_US
dc.relation.ispartofIrish Journal of Medical Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOzoneen_US
dc.subjectCystitisen_US
dc.subjectRatsen_US
dc.subjectOxidative stressen_US
dc.titleEvaluation of the effects of ozone therapy on Escherichia coli-induced cytitis in raten_US
dc.typeArticleen_US

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