Effect of micro-arc oxidation coatings with graphene oxide and graphite on osseointegration of titanium implants-an in vivo study

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dc.authoridKhurshid, Zohaib/0000-0001-7998-7335
dc.authoridFaheemuddin, Muhammad/0000-0003-2797-2806
dc.authoriddemirci, fatih/0000-0002-8744-5592
dc.authorwosidKhurshid, Zohaib/K-9314-2015
dc.authorwosidFaheemuddin, Muhammad/HKW-0750-2023
dc.authorwosiddemirci, fatih/ABG-8682-2020
dc.contributor.authorTekin, Bahar
dc.contributor.authorDundar, Serkan
dc.contributor.authorTekin, Samet
dc.contributor.authorSukuroglu, Ebru Emine
dc.contributor.authorKhurshid, Zohaib
dc.contributor.authorEzgi, Yusuf
dc.contributor.authorDemirci, Fatih
dc.date.accessioned2024-08-04T20:55:05Z
dc.date.available2024-08-04T20:55:05Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: This in vivo study evaluated the effect of graphene oxide and graphite coatings, coupled with the micro-arc oxidation (MAO) surface roughening technique, known for their mechanical strength, chemical stability, and antibacterial properties. The main objective was to assess the degree of improvement in osseointegration of titanium implants resulting from these interventions. Materials and methods: In this study, 32 female rats were utilized and randomly allocated into four groups (n = 8 each): machined surface titanium implants (control), those roughened by the MAO method, those coated with graphene oxide-doped MAO, and those with a graphite-doped MAO coating. Titanium implants were surgically placed in the right tibia of the rats. Rats undergoing no additional procedures during the 4-week experimental period were sacrificed at the end. Then, the implants and surrounding bone tissues were separated and embedded in acrylic blocks for reverse torque analysis. Using a digital torque device, the rotational force was applied to all samples using a hex driver and racquet until implant separation from the bone occurred, with the corresponding values recorded on the digital display. Then, statistical analysis was performed to analyze the data. Results: No statistically significant difference between the groups was observed in the biomechanical bone-implant connection levels (N/cm) (P = 0.268). Post-hoc tests were not required because no discernible differences were identified between the groups. Conclusion: Within the scope of this study, implants treated with the MAO method, along with those coated with graphene oxide- and graphite-doped MAO method, did not exhibit significant superiority in terms of osseointegration compared to machined surface titanium implants.en_US
dc.identifier.doi10.1016/j.sdentj.2024.01.013
dc.identifier.endpage595en_US
dc.identifier.issn1013-9052
dc.identifier.issn1658-3558
dc.identifier.issue4en_US
dc.identifier.pmid38690378en_US
dc.identifier.scopus2-s2.0-85184760369en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage591en_US
dc.identifier.urihttps://doi.org/10.1016/j.sdentj.2024.01.013
dc.identifier.urihttps://hdl.handle.net/11616/101810
dc.identifier.volume36en_US
dc.identifier.wosWOS:001230812100001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofSaudi Dental Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCoatingen_US
dc.subjectDental implantsen_US
dc.subjectGraphiteen_US
dc.subjectGraphene oxideen_US
dc.subjectMicro -arc oxidationen_US
dc.subjectOsseointegrationen_US
dc.titleEffect of micro-arc oxidation coatings with graphene oxide and graphite on osseointegration of titanium implants-an in vivo studyen_US
dc.typeArticleen_US

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