Evaluation of the relationship between serum high sensitive C-reactive protein and the elasticity properties of the aorta in patients with coronary artery ectasia

Basit Öğe Kaydı
dc.authorscopusid8708323200
dc.authorscopusid8708323300
dc.authorscopusid6508277687
dc.authorscopusid7801566797
dc.authorscopusid57193624275
dc.contributor.authorSincer I.
dc.contributor.authorAktürk E.
dc.contributor.authorAçikgöz N.
dc.contributor.authorErmiş N.
dc.contributor.authorKoşar M.F.
dc.date.accessioned2024-08-04T20:02:04Z
dc.date.available2024-08-04T20:02:04Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Previous studies have shown an association between high sensitive C-reactive protein (hsCRP) and arterial stiffness in most cardiovascular diseases. High sensitive C-reactive protein and arterial stiffness have been considered as independent predictors of cardiovascular mortality in cardiovascular disease. The aim of this study was to investigate the relationship between hsCRP, a marker of systemic inflammation and aortic stiffness in patients with coronary artery ectasia (CAE). Methods: Our study was designed as cross-sectional study. Serum hsCRP levels and aortic stiffness parameters were measured in CAE patients (n=28) and age - and gender-matched control subjects (n=25). Serum hsCRP levels were determined by an immunonephelometry assay. Aortic strain (AS) and aortic distensibility (AD) were calculated from the aortic diameters measured using M-mode echocardiography and blood pressure obtained by sphygmomanometry. Independent samples "t" test, Chi-square test and Spearman correlation test were used for statistical analysis. Results: Serum levels of hsCRP in CAE group were higher than in the controls (p<0.001). AS and AD were significantly decreased in CAE patients compared to the controls (p<0.001 and p<0.001, respectively). There were negative correlations between hsCRP and AS (r=-0.862; p<0.001), and AD (r=0.852; p<0.001) and a positive correlation between hsCRP, and ASI (r=0.852; p<0.001). Conclusion: We have demonstrated that there is a significant correlation between serum hsCRP levels and aortic stiffness in patients with CAE. These findings may indicate an important role of hsCRP in the pathogenesis of impaired aortic stiffness in coronary ectasia. ©Copyright 2011 by AVES Yaynclk Ltd.en_US
dc.identifier.doi10.5152/akd.2011.108
dc.identifier.endpage420en_US
dc.identifier.issn1302-8723
dc.identifier.issue5en_US
dc.identifier.pmid21712171en_US
dc.identifier.scopus2-s2.0-79960505753en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage414en_US
dc.identifier.urihttps://doi.org/10.5152/akd.2011.108
dc.identifier.urihttps://hdl.handle.net/11616/91399
dc.identifier.volume11en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAVESen_US
dc.relation.ispartofAnadolu Kardiyoloji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAortic distensibilityen_US
dc.subjectAortic stiffnessen_US
dc.subjectAortic strainen_US
dc.subjectCoronary artery ectasiaen_US
dc.subjectHigh sensitive c-reactive proteinen_US
dc.titleEvaluation of the relationship between serum high sensitive C-reactive protein and the elasticity properties of the aorta in patients with coronary artery ectasiaen_US
dc.title.alternativeKoroner ektazisi olan hastalarda aortun elastik özellikleri ile serum yüksek duyarlılıklı C-reaktif protein arasındaki ilişkinin de?erlendirilmesien_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu