Ghrelin and lipid levels in panic disorder before and after treatment and their relationship with agoraphobia

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dc.authorscopusid36987325300
dc.authorscopusid14036809400
dc.authorscopusid6602953248
dc.authorscopusid55903323700
dc.contributor.authorGul I.G.
dc.contributor.authorCumurcu B.E.
dc.contributor.authorKarlidag R.
dc.contributor.authorTurkoz Y.
dc.date.accessioned2024-08-04T19:59:24Z
dc.date.available2024-08-04T19:59:24Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: We aimed to evaluate serum ghrelin (GHR) levels and lipid profile in panic disorder (PD), with and without agoraphobia, and to compare these parameters before and after treatment. Subjects and methods: The GHR and lipid profiles were measured in blood samples taken from 31 PD patients with agoraphobia, 22 PD patients without agoraphobia, and 53 control group subjects. 23 of the 53 patients who were prescribed 20 to 40 mg/day paroxetine had continued treatment. The 23 patients who had continued treatment were measured again at the end of twelve weeks. Results: The GHR and triglyceride (TRG), total cholesterol (Total-C), low-density lipoproteins (LDL-C), and very low-density lipoproteins (VLDL-C) levels were higher in the PD with agoraphobia group than the PD without agoraphobia and control groups. The 23 patients that had continued their treatment were re-evaluated, and the serum GHR, Total-C levels, and BMI after treatment were significantly decreased, compared to the values before treatment. Conclusions: There may be a pathophysiological relationship between the GHR and lipid profiles that interact with each other in PD. In fact, this relationship was more marked in PD with agoraphobia than in PD without agoraphobia. © Medicinska naklada - Zagreb, Croatia.en_US
dc.identifier.endpage258en_US
dc.identifier.issn0353-5053
dc.identifier.issue3en_US
dc.identifier.pmid26400133en_US
dc.identifier.scopus2-s2.0-84955572647en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage250en_US
dc.identifier.urihttps://hdl.handle.net/11616/90603
dc.identifier.volume27en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMedicinska Naklada Zagreben_US
dc.relation.ispartofPsychiatria Danubinaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAgoraphobiaen_US
dc.subjectCholesterolen_US
dc.subjectGhrelinen_US
dc.subjectLipiden_US
dc.subjectPanic disorderen_US
dc.titleGhrelin and lipid levels in panic disorder before and after treatment and their relationship with agoraphobiaen_US
dc.typeArticleen_US

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