Neuromuscular transmission in hypoxemic patients with chronic obstructive pulmonary disease

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dc.authoridKamisli, Ozden/0000-0003-1114-7860
dc.authoridKamisli, Suat/0000-0003-4281-3301
dc.authoridKamisli, Ozden/0000-0003-1114-7860
dc.authoridozcan, abdulcemal/0000-0002-6759-7556
dc.authoridKablan, Yüksel/0000-0002-5581-2968
dc.authoridGulbas, Gazi/0000-0002-9435-8307
dc.authoridErmis, Hilal/0000-0002-1764-9098;
dc.authorwosidKamisli, Ozden/AAA-6553-2020
dc.authorwosidKamisli, Suat/AAC-2706-2021
dc.authorwosidKamisli, Ozden/JVZ-0145-2024
dc.authorwosidozcan, abdulcemal/B-1348-2008
dc.authorwosidKablan, Yüksel/AAB-5049-2021
dc.authorwosidGulbas, Gazi/ABI-5182-2020
dc.authorwosidKamisli, Suat/JVN-4663-2024
dc.contributor.authorGulbas, Gazi
dc.contributor.authorKaplan, Yuksel
dc.contributor.authorKamisli, Ozden
dc.contributor.authorErmis, Hilal
dc.contributor.authorKamisli, Suat
dc.contributor.authorOzcan, Cemal
dc.date.accessioned2024-08-04T20:37:46Z
dc.date.available2024-08-04T20:37:46Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractMany studies have focused on the systemic effects of chronic obstructive pulmonary disease (COPD), but none has examined neuromuscular junction transmission (NMT). We evaluated NMT dysfunction using single-fiber electromyography (SFEMG) in patients with COPD. Twenty patients with COPD and 20 age-matched healthy controls were included in the study. All patients and controls underwent SFEMG. Abnormal NMT was found in seven of 20 patients (35%), but in none of the control subjects. The COPD patients were subgrouped according to the presence of hypoxemia. The patients with normoxemia were classified as Group 1, and the patients with hypoxemia were classified as Group 2. Abnormal NMT was found in six patients in Group 2 and in one in Group 1. While there was significant difference in terms of abnormal NMT between Group 2 and the controls, there was none between Group 1 and the controls. Our results show that NMT abnormalities can be present in hypoxemic patients with COPD. (C) 2013 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.resp.2013.07.017
dc.identifier.endpage116en_US
dc.identifier.issn1569-9048
dc.identifier.issn1878-1519
dc.identifier.issue1en_US
dc.identifier.pmid23886635en_US
dc.identifier.scopus2-s2.0-84881496392en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage112en_US
dc.identifier.urihttps://doi.org/10.1016/j.resp.2013.07.017
dc.identifier.urihttps://hdl.handle.net/11616/96170
dc.identifier.volume189en_US
dc.identifier.wosWOS:000326059100016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofRespiratory Physiology & Neurobiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCOPDen_US
dc.subjectSingle-fiber EMGen_US
dc.subjectNeuromuscular transmissionen_US
dc.subjectHypoxemiaen_US
dc.titleNeuromuscular transmission in hypoxemic patients with chronic obstructive pulmonary diseaseen_US
dc.typeArticleen_US

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