Tumor Diameter for Hepatocellular Carcinoma: Why Should Size Matter?

dc.authoridKayaalp, Cuneyt/0000-0003-4657-2998
dc.authorwosidKayaalp, Cuneyt/AAH-1764-2021
dc.contributor.authorUsta, Sertac
dc.contributor.authorKayaalp, Cuneyt
dc.date.accessioned2024-08-04T20:48:53Z
dc.date.available2024-08-04T20:48:53Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose There are two main goals in hepatocellular carcinoma management, the first is long term survival and the second is the low recurrence rate after the treatment. Therefore, a lot of selection criteria defined for each treatment method and tumor size is one of the most important parameter in almost all of them. Methods In this review, importance of diamater in hepatocellular carcinoma is reviewed. Results Many reports showed a significant association between increase in maximum tumor diameter and microvascular invasion. Patients with larger tumors are more likely to have poorly differentiated tumors. Increased regional and distant metastasis of tumors were observed in the larger size hepatocellular carcinoma. Liver transplantation represents the best treatment option for patients with decompensated liver cirrhosis and hepatocellular carcinoma. Conclusions Combined with biological, inflammatory, radiological, pathological and genetic markers that predict the biological behavior of the tumor, today, tumor size is one of the best aggressiveness markers until new markers are found. So, tumor size is matter.en_US
dc.identifier.doi10.1007/s12029-020-00483-z
dc.identifier.endpage1117en_US
dc.identifier.issn1941-6628
dc.identifier.issn1941-6636
dc.identifier.issue4en_US
dc.identifier.pmid32851543en_US
dc.identifier.scopus2-s2.0-85089913576en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1114en_US
dc.identifier.urihttps://doi.org/10.1007/s12029-020-00483-z
dc.identifier.urihttps://hdl.handle.net/11616/99497
dc.identifier.volume51en_US
dc.identifier.wosWOS:000565029000001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Gastrointestinal Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTumor sizeen_US
dc.subjectTumor diameteren_US
dc.subjectHepatocellular carcinomaen_US
dc.titleTumor Diameter for Hepatocellular Carcinoma: Why Should Size Matter?en_US
dc.typeReview Articleen_US

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