Electrochemical Determination of Norepinephrine at Poly (p-aminobenzenesulfonic Acid) Modified Sensor

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dc.authoridERDOGDU, GAMZE/0000-0002-8114-6946
dc.authoridKuyumcu Savan, Ebru/0000-0002-8851-0907
dc.authorwosidERDOGDU, GAMZE/ABG-7776-2020
dc.authorwosidKuyumcu Savan, Ebru/E-3430-2019
dc.contributor.authorYagci, Sevket Zisan
dc.contributor.authorSavan, Ebru Kuyumcu
dc.contributor.authorErdogdu, Gamze
dc.date.accessioned2024-08-04T20:47:25Z
dc.date.available2024-08-04T20:47:25Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: In this study, it was aimed to prepare an electrochemical sensor capable of assigning Norepinephrine in the presence of an interference such as ascorbic acid. Methods: A sensitive modified sensor was prepared by electrodeposition of p-aminobenzenesulfonic acid (p-ABSA) to the glassy carbon electrode by cyclic voltammetry. The electrooxidation of Norepinephrine was accomplished by cyclic and differential pulse voltammetry. Results: The current values were enhanced and the peak potentials of Norepinephrine and ascorbic acid were separated at the sensor compared to the bare electrode. There was linearity between the oxidation current and concentration of Norepinephrine ranging from 0.5 to 99.8 mu M in phosphate buffer solution at pH 7.0. The limit of detection was 10.0 nM and the sensitivity was 0.455 mu A/mu M. Conclusion: The determination of Norepinephrine was successfully performed in real samples such as blood serum and urine at the poly (p-ABSA) sensor. To the best of our knowledge, this is the first study to detect Norepinephrine in the presence of ascorbic acid at poly (p-ABSA) modified sensor in the literature.en_US
dc.description.sponsorshipResearch Fund Unit of Inonu University [APYB: 2010/30]en_US
dc.description.sponsorshipThe Research Fund Unit of Inonu University financially supported this study (Grant no APYB: 2010/30).en_US
dc.identifier.doi10.2174/1573412915666190212160442
dc.identifier.endpage600en_US
dc.identifier.issn1573-4129
dc.identifier.issn1875-676X
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85086919265en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage591en_US
dc.identifier.urihttps://doi.org/10.2174/1573412915666190212160442
dc.identifier.urihttps://hdl.handle.net/11616/99366
dc.identifier.volume16en_US
dc.identifier.wosWOS:000541970700016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherBentham Science Publ Ltden_US
dc.relation.ispartofCurrent Pharmaceutical Analysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNorepinephrineen_US
dc.subjectascorbic aciden_US
dc.subjectelectrochemical sensoren_US
dc.subjectp-aminobenzenesulfonic aciden_US
dc.subjectvoltammetryen_US
dc.subjectcatecholamineen_US
dc.titleElectrochemical Determination of Norepinephrine at Poly (p-aminobenzenesulfonic Acid) Modified Sensoren_US
dc.typeArticleen_US

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