Decreased adrenomedullin and total nitrite levels in breast milk of preeclamptic women

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dc.authoridBalat, Ayse/0000-0002-8904-1348
dc.authoridYurekli, Muhittin/0000-0002-5830-8564;
dc.authorwosidcekmen, mustafa baki/G-6122-2011
dc.authorwosidBalat, Ayse/JOZ-8426-2023
dc.authorwosidYurekli, Muhittin/B-4414-2016
dc.authorwosiderbagci, ayse binnur/C-2385-2009
dc.contributor.authorCekmen, MB
dc.contributor.authorBalat, A
dc.contributor.authorBalat, O
dc.contributor.authorAksoy, F
dc.contributor.authorYurekli, M
dc.contributor.authorErbagci, AB
dc.contributor.authorSahinoz, S
dc.date.accessioned2024-08-04T20:13:36Z
dc.date.available2024-08-04T20:13:36Z
dc.date.issued2004
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To observe the adrenomedullin (AM) and total nitrite levels in the milk of preeclamptic and normal pregnant women. Design and methods: Fifteen women with preeclampsia and 15 normal pregnant women were included in the study. Total nitrite was quantitated by Griess reaction, while AM was measured by HPLC. Results: The levels of AM and total nitrite in colostrum and 30th-day breast milk were decreased in preeclamptics. Total. nitrite levels (mumol/l) were 56.09 +/- 11.18 vs. 82.20 +/- 12.01, P < 0.05, in colostrum of preeclamptics and controls, respectively. The level of total nitrite was 37.75 +/- 12.10 vs. 53.28 +/- 10.25, P < 0.05, in 30th-day milk of same patients. AM levels (pg/ml) were 11.18 +/- 1.11 vs. 16.59 +/- 1.24, P < 0.0001, in colostrum of preeclamptics and controls, respectively. In 30th-day milk of same patients, AM levels were 8.41 +/- 1.39 vs. 12.18 +/- 1.48, P < 0.005, respectively. Conclusion: This report shows for the first time that human milk has decreased levels of AM and total nitrite in preeclampsia. (C) 2003 The Canadian Society of Clinical Chemists. All rights reserved.en_US
dc.identifier.doi10.1016/j.clinbiochem.2003.10.010
dc.identifier.endpage148en_US
dc.identifier.issn0009-9120
dc.identifier.issue2en_US
dc.identifier.pmid14725946en_US
dc.identifier.scopus2-s2.0-0346023034en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage146en_US
dc.identifier.urihttps://doi.org/10.1016/j.clinbiochem.2003.10.010
dc.identifier.urihttps://hdl.handle.net/11616/93699
dc.identifier.volume37en_US
dc.identifier.wosWOS:000188746800010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofClinical Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectadrenomedullinen_US
dc.subjectbreast milken_US
dc.subjectnitric oxideen_US
dc.subjectpreeclampsiaen_US
dc.titleDecreased adrenomedullin and total nitrite levels in breast milk of preeclamptic womenen_US
dc.typeArticleen_US

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