Evaluation of the treatment results of laryngeal carcinoma: our experience over 10 years
Küçük Resim Yok
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Tubitak Scientific & Technological Research Council Turkey
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: To retrospectively analyze the treatment results for laryngeal carcinoma and to find the impact of the clinical parameters on the survival of the patients. Materials and methods: The medical records of 150 consecutive patients, operated on for laryngeal squamous cell carcinoma between 1991 and 2009, were reviewed. Tumor localization, TNM stages, treatment modalities, radiotherapy, second primary tumors, and tumor recurrence were recorded, and the survival data were obtained. Results: Neck metastasis was rare (3.6%) in T1 and T2 glottic tumors, while there was a significant increase in the rate of N+ neck (35%) in T3 and T4 glottic tumors (P < 0.05). N+ neck was encountered in 28% of the early and 33% of the late-stage supraglottic cancers (P > 0.05). There was a significant relation between survival and tumor recurrence (P < 0.05), whereas the other clinical parameters were not associated with survival (P > 0.05). The risk for death of the disease increased by 63.3% when tumor recurrence occurred (odds ratio = 6.3573). Conclusion: Aggressive treatment of the primary tumor and neck may eliminate the impact of advanced tumor stage on survival. Local and regional recurrence and second primary diagnosis are the most important factors involved in survival in laryngeal carcinoma.
Açıklama
Anahtar Kelimeler
Laryngeal carcinoma, treatment, prognosis, recurrence, survival
Kaynak
Turkish Journal of Medical Sciences
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
42
