LC-MS/MS Analysis, Antioxidant Properties and Inhibition Effect on Some Important Metabolic Enzymes of Nicotiana rustica L

Basit Öğe Kaydı
dc.authoridIşık, Mesut/0000-0002-4677-8104
dc.authoridGÜZEL, Abdussamat/0000-0001-7810-4510
dc.authoridKAYGISIZ, FEYZA/0000-0002-2899-2289
dc.authoridTAKIM, KASIM/0000-0003-4631-1982
dc.authorwosidIşık, Mesut/ABG-4558-2020
dc.authorwosidGÜZEL, Abdussamat/GXG-4734-2022
dc.authorwosidGUZEL, ABDUSSAMAT/AAI-1866-2019
dc.contributor.authorNecip, Adem
dc.contributor.authorIsik, Mesut
dc.contributor.authorGuzel, Abdussamat
dc.contributor.authorTakim, Kasim
dc.contributor.authorKaygisiz, Feyza
dc.date.accessioned2024-08-04T20:10:35Z
dc.date.available2024-08-04T20:10:35Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBeing widely used since its discovery, tobacco contains many chemical substances including nitric oxide, hydrocarbons, aldehydes, phenols, quinone and semiquinone radicals, and causes the formation of oxygen-induced free radicals directly or indirectly. Therefore, it is important to know the oxidant/antioxidant properties, phenolic content of Nicotiana rustica Linn., and the effect studies on Paraoxonase (PON 1) and Acetylcholinesterase (AChE) which are important metabolic enzymes. In the study, the effect of extracts (water and methanol) of Nicotiana rustica Linn on PON 1 and AChE enzyme activity was examined. Water extract of Nicotiana rustica Linn Maras Powder with walnut, (MPWW) and methanol extract Maras Powder with Nicotiana rustica, (MPNR), Maras Powder with walnut, (MPWW) and Maras Powder with copper cauldron, (MPCC) had an inhibitory effect on AChE (IC50 values in the range of 0.104-0.203 mg ml(-1)). Also water extract MPCC and methanol extract MPNR, MPWW and MPCC showed an inhibition effect on PON 1 (IC50 values 0.013-0.225 mg ml(-1)). MPNR water extract showed the highest activity with 26% DPPH radical scavenging activity. MPCC water extract showed a 13% ABTS radical scavenging activity.en_US
dc.identifier.doi10.18016/ksutarimdoga.vi.856514
dc.identifier.endpage938en_US
dc.identifier.issn2619-9149
dc.identifier.issue5en_US
dc.identifier.startpage930en_US
dc.identifier.trdizinid1121764en_US
dc.identifier.urihttps://doi.org/10.18016/ksutarimdoga.vi.856514
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1121764
dc.identifier.urihttps://hdl.handle.net/11616/92886
dc.identifier.volume24en_US
dc.identifier.wosWOS:000704525400003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherKahramanmaras Sutcu Imam Univ Rektorluguen_US
dc.relation.ispartofKsu Tarim Ve Doga Dergisi-Ksu Journal of Agriculture and Natureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMaras Grassen_US
dc.subjectPhenolicen_US
dc.subjectAntioxidanten_US
dc.subjectEnzyme inhibitionen_US
dc.subjectParaoxonaseen_US
dc.titleLC-MS/MS Analysis, Antioxidant Properties and Inhibition Effect on Some Important Metabolic Enzymes of Nicotiana rustica Len_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu