Evaluation of the left ventricular function with tissue tracking and tissue Doppler echocardiography in pediatric malignancy survivors after anthracycline therapy

Yükleniyor...
Küçük Resim

Tarih

2008

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Echocardıography-A Journal Of Cardıovascular Ultrasound And Allıed Technıques

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Although the anthracyclines have gained widespread use in the treatment of childhood hematologicalmalignancies and solid tumors, cardiotoxicity is the major limiting factor in the use of anthracyclines.The aim of this study was to assess the mitral annular displacement by tissue tracking in pediatricmalignancy survivors who had been treated with anthracycline groups chemotheraphy and comparewith the tissue Doppler and conventional two dimensional measurements and Doppler indices. In thisstudy, 32 pediatric malignancy survivors and 22 healthy children were assessed with 2D, colour-codedechocardiography. Left ventricular ejection fraction, fractional shortening, stroke volume, cardiacoutput, cardiac index and diastolic functions were measured. All subjects were assessed with tissueDoppler echocardiography, mitral annular displacements, and also with tissue tracking method. Wedetected that peak velocity of the early rapid filling on tissue Doppler (E′) was lower (p < 0.05) andthe ratio of early peak velocity of rapid filling on pulse Doppler to tissue Doppler (E/E′) values werestatistically higher in patient group than control group (p < 0.05). Myocardial performance indexvalues were also higher in patient group than the control group (p < 0.01). It appears that MPI isa useful echocardiograghic method than tissue tracking of mitral annular displacement in patientswith pediatric cancer survivors who had subclinical diastolic dysfunction. (ECHOCARDIOGRAPHY,Volume 25, September 2008)

Açıklama

Echocardıography-A Journal Of Cardıovascular Ultrasound And Allıed Technıques , 25(8), 880–887.

Anahtar Kelimeler

Kaynak

Echocardıography-A Journal Of Cardıovascular Ultrasound And Allıed Technıques

WoS Q Değeri

Scopus Q Değeri

Cilt

25

Sayı

8

Künye

Karakurt, C., Koçak, G., & Özgen, Ü. (2008). Evaluation Of The Left Ventricular Function With Tissue Tracking And Tissue Doppler Echocardiography İn Pediatric Malignancy Survivors After Anthracycline Therapy. Echocardıography-A Journal Of Cardıovascular Ultrasound And Allıed Technıques , 25(8), 880–887.