Histopathological changes of nasal mucosa after nasal packing with Merocel

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dc.authoridAslan, Mehmet/0000-0002-0707-9984
dc.authoridTAN, MEHMET/0000-0001-8557-0886
dc.authoridAslan, Mehmet/0000-0002-0707-9984
dc.authoridçiçek, mehmet turan/0000-0002-0997-7729
dc.authorwosidAslan, Mehmet/ABI-8036-2020
dc.authorwosidTAN, MEHMET/ABI-7574-2020
dc.authorwosidAslan, Mehmet/AED-5913-2022
dc.authorwosidçiçek, mehmet turan/AAC-2468-2020
dc.contributor.authorTan, M.
dc.contributor.authorBayindir, T.
dc.contributor.authorCicek, M. T.
dc.contributor.authorAslan, M.
dc.contributor.authorGul, M.
dc.date.accessioned2024-08-04T20:50:56Z
dc.date.available2024-08-04T20:50:56Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective To determine histopathological changes in nasal mucosa associated with duration of nasal packing with Merocel tampons. Methods This study included 24 healthy rabbits, 6 rabbits per group. In group A, no tampon was applied. In group B, Merocel nasal tampons were applied and removed after 24 hours. In group C, the tampons were removed after 48 hours. In group D, the tampons were removed after 5 days. Specimens were obtained from the septum of each rabbit, including cartilage. Histopathological examination was performed. Results Significant differences were observed in terms of inflammatory infiltration and loss of cilia between groups A and B. Significant differences were also observed in terms of inflammatory infiltration, haematoma, cilia loss, epithelium dysplasia and cartilage degeneration between groups B and C. There were significant differences in terms of cilia loss, epithelium dysplasia and subepithelial fibrosis between groups C and D. Cartilage degeneration was mild in one animal in group B and in two animals in group C, and was moderate in four animals in group C. Conclusion It is recommended that Merocel nasal tampons are removed within 48 hours to preserve nasal mucosal function. Keeping the pack longer may cause cartilage degeneration and other complications.en_US
dc.identifier.doi10.1017/S0022215121004205
dc.identifier.endpage754en_US
dc.identifier.issn0022-2151
dc.identifier.issn1748-5460
dc.identifier.issue8en_US
dc.identifier.pmid34924066en_US
dc.identifier.scopus2-s2.0-85121743119en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage750en_US
dc.identifier.urihttps://doi.org/10.1017/S0022215121004205
dc.identifier.urihttps://hdl.handle.net/11616/100377
dc.identifier.volume136en_US
dc.identifier.wosWOS:000810789700001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCambridge Univ Pressen_US
dc.relation.ispartofJournal of Laryngology and Otologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEpistaxisen_US
dc.subjectSeptoplastyen_US
dc.subjectNasal Packingen_US
dc.titleHistopathological changes of nasal mucosa after nasal packing with Merocelen_US
dc.typeArticleen_US

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