Urine xanthine oxidase and myeloperoxidase activity in pediatric urinary tract infections

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dc.authorscopusid14024194500
dc.authorscopusid6701425167
dc.authorscopusid8568915200
dc.authorscopusid13907825000
dc.authorscopusid22953768800
dc.authorscopusid25654511500
dc.contributor.authorDavutoglu M.
dc.contributor.authorKarabiber H.
dc.contributor.authorKurutas E.B.
dc.contributor.authorOlgar S.
dc.contributor.authorGuler E.
dc.contributor.authorAtli Y.
dc.date.accessioned2024-08-04T19:59:09Z
dc.date.available2024-08-04T19:59:09Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To investigate the relationships between urinary tract infection (UTI), and activity of antioxidant enzymes, xanthine oxidase (XO) and myeloperoxidase (MPO) in urine of children with UTI Design: Prospective observational study Setting: Department of Pediatrics, Kahramanmaras Sutcu Imam University, Faculty of Medicine, Turkey Subjects and Methods: A total of 115 random children admitted to our hospital for urinary symptoms, 61 girls and 54 boys, aged between 2 and 15 years (average 10 years) were included. Study subjects were divided into four groups: Group 1 consisted of 29 pyuria positive and urine culture negative children; Group 2 included 30 children with pyuria and positive urine culture; Group 3 included 26 pyuria negative and urine culture positive children and Group 4 included 30 with pyuria and negative urine culture. Measurement of urine XO and MPO activity were performed spectrophotometrically. Intervension: Urine samples Main Outcome Measures: Antioxidant enzyme activity levels in urine were examined in children with urinary tract infection. Results: Urinary XO activities in Group 2 were significantlyhigher compared with other groups (p < 0.001, p = 0.001 and p < 0.001, respectively). SignificantlydifferentMPOactivitieswere found between Group 1 and Group 2 (p = 0.007). However, no significantdifferencewasfoundbetweenGroup3 and 4. Conclusion: SignificantlyincreasedMPOandXOenzymeactivity was found in children with UTI. Measurement of MPO and XO activity may be useful in children with urinary symptoms to diagnose UTI, before obtaining a positive urine culture.en_US
dc.identifier.endpage202en_US
dc.identifier.issn0023-5776
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84890299605en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage199en_US
dc.identifier.urihttps://hdl.handle.net/11616/90432
dc.identifier.volume45en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofKuwait Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectUrinary tract infectionen_US
dc.subjectUrine myeloperoxidaseen_US
dc.subjectUrine xanthine oxidaseen_US
dc.titleUrine xanthine oxidase and myeloperoxidase activity in pediatric urinary tract infectionsen_US
dc.typeArticleen_US

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