Synthesis and antimicrobial activity of bulky 3,5-di-tert-butyl substituent-containing silver-N-heterocyclic carbene complexes

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dc.authoridÖzdemir, İsmail/0000-0001-6325-0216
dc.authoridGünal, Selami/0000-0002-4752-5176
dc.authorwosidÖzdemir, İsmail/ABI-5192-2020
dc.authorwosidÖzdemir, İlknur/AAA-6216-2021
dc.authorwosidGünal, Selami/AAA-7246-2021
dc.contributor.authorKaloglu, Nazan
dc.contributor.authorOzdemir, Ilknur
dc.contributor.authorGunal, Selami
dc.contributor.authorOzdemir, Ismail
dc.date.accessioned2024-08-04T20:43:10Z
dc.date.available2024-08-04T20:43:10Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractA series of novel benzimidazolium bromides containing bulky 3,5-di-tert-butyl group were synthesized in high yields as N-heterocyclic carbene (NHC) ligands. These NHC ligands were metallated with Ag2O under moderate conditions to give novel silver-NHC complexes. The structures of all compounds were characterized using H-1 NMR, (CNMR)-C-13, infrared and elemental analysis techniques, which supported the proposed structures. The silver-NHC complexes were screened for their in vitro antimicrobial activities against the standard bacterial strains Enterococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa and the fungal strains Candida albicans and C. tropicalis. The results showed that most of the silver-NHC complexes inhibited the growth of all bacterial strains and fungal strains and were found to display effective antimicrobial activity against different microorganisms.en_US
dc.description.sponsorshipTechnological and Scientific Research Council of Turkey (TUBITAK) [TBAG-(108T411)]; Inonu University Research Fund [IU-BAP: 2015/41-Gudumlu]en_US
dc.description.sponsorshipTechnological and Scientific Research Council of Turkey (TUBITAK), Grant/Award Number: TBAG-(108T411); Inonu University Research Fund, Grant/Award Number: IU-BAP: 2015/41-Gudumluen_US
dc.identifier.doi10.1002/aoc.3803
dc.identifier.issn0268-2605
dc.identifier.issn1099-0739
dc.identifier.issue11en_US
dc.identifier.scopus2-s2.0-85019270928en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1002/aoc.3803
dc.identifier.urihttps://hdl.handle.net/11616/97822
dc.identifier.volume31en_US
dc.identifier.wosWOS:000413765100060en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofApplied Organometallic Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectantimicrobial activityen_US
dc.subjectbenzimidazolium halidesen_US
dc.subjectN-heterocyclic carbeneen_US
dc.subjectsilver-NHC complexesen_US
dc.titleSynthesis and antimicrobial activity of bulky 3,5-di-tert-butyl substituent-containing silver-N-heterocyclic carbene complexesen_US
dc.typeArticleen_US

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