Application of Single-Walled Carbon Nanotube and Poly (3-Methylthiophene) Modified Sensors for Electrochemical Determination of Levodopa and Benserazide

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dc.authoridERDOGDU, GAMZE/0000-0002-8114-6946
dc.authoridKuyumcu Savan, Ebru/0000-0002-8851-0907
dc.authorwosidERDOGDU, GAMZE/ABG-7776-2020
dc.authorwosidKuyumcu Savan, Ebru/E-3430-2019
dc.contributor.authorSavan, Ebru Kuyumcu
dc.contributor.authorErdogdu, Gamze
dc.date.accessioned2024-08-04T20:46:58Z
dc.date.available2024-08-04T20:46:58Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractSixteen electrochemical electrodes were prepared by modifying the electro-polymerized 3-methylthiophene to the below and above of the single-walled carbon nanotubes (SWCNTs) dispersion that dripped onto glassy carbon electrode. Determination of benserazide (BS) and levodopa (LD) in the presence of ascorbic acid (AA) was performed by differential pulse voltammetry (DPV) technique to find out which of these electrodes gave the best and fastest simultaneous response. The highest resolution and current densities were achieved with the electrode that 20 mu L 1.0% SWCNT was dribbled onto the bare electrode. The morphology and structure of modified electrode were characterized by scanning electron microscopy. Under optimum conditions AA, BS and LD gave sensitive oxidation peaks at nearly 90, 210 and 320 mV, respectively. The oxidation currents increased linearly with concentration of BS (50-100 mu M) and LD (5.0-9.5 mu M) in phosphate buffer solution (pH 7.0). The detection limits obtained by DPV were 3.0 mu M for BS and 1.1 mu M for LD. Additionally, the proposed modified sensor was applied successfully to biological fluids and tablet samples. The results proved that the modified sensor showed excellent selectivity, repeatability and reproducibility with high stability and accuracy.en_US
dc.description.sponsorshipResearch Fund Unit of Inonu University [APYB: 2013/54]en_US
dc.description.sponsorshipThe Research Fund Unit of Inonu University financially supported this study (Grant no APYB: 2013/54).en_US
dc.identifier.endpage597en_US
dc.identifier.issn2008-4226
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85075842058en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage585en_US
dc.identifier.urihttps://hdl.handle.net/11616/99080
dc.identifier.volume11en_US
dc.identifier.wosWOS:000470101100003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherUniv Tehran, Fac Chemistry, Center Excellence Electrochemistryen_US
dc.relation.ispartofAnalytical & Bioanalytical Electrochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBenserazideen_US
dc.subjectLevodopaen_US
dc.subjectSingle-walled carbon nanotubeen_US
dc.subjectElectrochemical sensoren_US
dc.titleApplication of Single-Walled Carbon Nanotube and Poly (3-Methylthiophene) Modified Sensors for Electrochemical Determination of Levodopa and Benserazideen_US
dc.typeArticleen_US

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