Avascular necrosis of the femoral head in sickle cell disease
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Dosyalar
Tarih
2017
Yazarlar
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info:eu-repo/semantics/openAccess
Özet
Sickle cell disease (SCD) is a life threatening hemoglobinopathy effecting various systems. SCD is an important health issue in
Turkey, especially in the southern areas. The patients suffer from complications resulting from vaso-occlusion and hemolysis.
Twenty- two percent of children and 49% of adults with Hb SS are reported to have avascular necrosis (AVN). The SCD panel 2014
recommends to evaluate all children with SCD and hip pain for AVN by history, physical examination, radiography and magnetic
resonance imaging. Long term daily oral treatment with hydroxyurea has been shown to reduce complications in SCD.
Hydroxyurea does not only increase the level of fetal hemoblobin but also it causes a reduction in the number of circulating
leukocytes, increases red blood cell size. Here in two SCD patients who developed AVN in femoral head are reported and it is
aimed to raise awareness to this morbidity and the importance of regular use and dosage escalation of hydroxyurea therapy.
Açıklama
Anahtar Kelimeler
Kaynak
Annals of Medical Research
WoS Q DeÄŸeri
Scopus Q DeÄŸeri
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Künye
Karakurt, N., & Ali Deveci, M. (2021). Avascular necrosis of the femoral head in sickle cell disease . Annals of Medical Research
