Proton MRS in Behcet's disease with and without neurological findings

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dc.authoridozcan, abdulcemal/0000-0002-6759-7556
dc.authoridKarlıdağ, Rifat/0000-0002-3650-0774
dc.authorwosidkarlıdağ, rıfat/AAB-4255-2021
dc.authorwosidSaraç, Kaya/ABI-1091-2020
dc.authorwosidDusak, Abdurrahim/A-7826-2019
dc.authorwosidozcan, abdulcemal/B-1348-2008
dc.authorwosidKarlıdağ, Rifat/AAB-4281-2021
dc.contributor.authorBaysal, T
dc.contributor.authorOzisik, HI
dc.contributor.authorKarlidag, R
dc.contributor.authorSarac, K
dc.contributor.authorBaysal, O
dc.contributor.authorDusak, A
dc.contributor.authorHazneci, E
dc.date.accessioned2024-08-04T20:13:36Z
dc.date.available2024-08-04T20:13:36Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOur aim was to investigate whether neurological impairment in Behcet's disease (BD) can be assessed by means of proton MRS and whether it can assist in prognosis. We used single-voxel MRS to measure metabolites in regions of normal-appearing pons, basal ganglia and periventricular white matter (PWM) in 32 patients with chronic BD patients with and without neurological deficits and 29 control subjects. Patients had significantly higher N-acetylaspartate (NAA)/creatine (Cr) and choline (Cho)/Cr ratios in the basal ganglia than the controls. The Cho/Cr ratio in the PWM was also significantly higher in the patients. MRS enabled clear discrimination of patients and controls and also revealed spectral differences between non-neuro-Behcet's disease and neuro-Behcet's disease in the basal ganglia. MRS can be used to assess brain involvement in BD even if structural changes are absent.en_US
dc.identifier.doi10.1007/s00234-003-1052-7
dc.identifier.endpage864en_US
dc.identifier.issn0028-3940
dc.identifier.issn1432-1920
dc.identifier.issue12en_US
dc.identifier.pmid14593444en_US
dc.identifier.scopus2-s2.0-0346025638en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage860en_US
dc.identifier.urihttps://doi.org/10.1007/s00234-003-1052-7
dc.identifier.urihttps://hdl.handle.net/11616/93700
dc.identifier.volume45en_US
dc.identifier.wosWOS:000186956400003en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofNeuroradiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBehcet's diseaseen_US
dc.subjectbrainen_US
dc.subjectmagnetic resonance spectroscopyen_US
dc.titleProton MRS in Behcet's disease with and without neurological findingsen_US
dc.typeArticleen_US

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