Comparison of the effects of nicardipine and remifentanil on surgical visual field and hemodynamic parameters in tympanomastoidectomy cases

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dc.contributor.authorKaraaslan, Erol
dc.contributor.authorTan, Mehmet
dc.contributor.authorOzkan, Ahmet Selim
dc.contributor.authorGülçek, İlham
dc.contributor.authorSarıtoy, Celal
dc.date.accessioned2026-04-04T13:14:36Z
dc.date.available2026-04-04T13:14:36Z
dc.date.issued2024
dc.departmentİnönü Üniversitesi
dc.description.abstractIn this study; We aimed to compare the surgical visual field and hemodynamic effects of Nicardipine and Remifentanil in microscopic tympanomastoidectomy patients. The study was planned as a prospective, double-blind, and randomized clinical trial. A total of 64 patients aged between 18 and 65 were included in the study and the patients were randomized into 2 groups: Group N (Nicardipine=32) and Group R (Remifentanil=32). The input data were measured at pre-induction (T0), 5 minutes post-incision (T1), 20 minutes post-incision (T2), mastoidectomy during the tour (T3), cholesteatoma clearance (T4), grafting (T5), extubation (T6), 10 minutes post-extubation (T7), at the time of admission to the post-anesthesia care unit (PACU) (T8) and the 15th minute (T9) in PACU along with hemodynamic parameters values. In the evaluation of the visibility of the surgical field, the Boezaart Scale was used. There was no significant difference in demographic data in both groups. Considering the hemodynamic parameters between the groups, HR values were higher in Group N during the whole period (T1-T9) (p<0.05). T1, T6, T7, and T8, while DAB and MAP were lower in Group N. No difference was observed between the groups in terms of Boezaart Scoring, nausea-vomiting and pain scoring. Remifentanil and Nicardipine provided similar surgical field visual quality in CH application in tympanomastoidectomy cases. We think that nicardipine may be preferred in cases with sensitivity to the pathological effects of bradycardia because it does not have a bradycardia-producing effect.
dc.identifier.doi10.5455/medscience.2024.07.089
dc.identifier.endpage860
dc.identifier.issn2147-0634
dc.identifier.issue4
dc.identifier.startpage854
dc.identifier.trdizinid1304405
dc.identifier.urihttps://doi.org/10.5455/medscience.2024.07.089
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1304405
dc.identifier.urihttps://hdl.handle.net/11616/107313
dc.identifier.volume13
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofMedicine Science
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TR_20250329
dc.subjectAnestezi
dc.subjectKulak
dc.subjectBurun
dc.subjectBoğaz
dc.titleComparison of the effects of nicardipine and remifentanil on surgical visual field and hemodynamic parameters in tympanomastoidectomy cases
dc.typeArticle

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